Rchr
J-GLOBAL ID:200901038046115541   Update date: Feb. 06, 2024

Goshima Yoshio

ゴシマ ヨシオ | Goshima Yoshio
Homepage URL  (2): http://www-user.yokohama-cu.ac.jp/~pharmac/index.htmlhttp://www-user.yokohama-cu.ac.jp/~pharmac/en_index.html
Research field  (4): Neuroanatomy and physiology ,  Neuroscience - general ,  Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (14): 包括脳ネットワーク ,  immunological and allergic diseases ,  Schizophrenia ,  Alzheimer's disease ,  semaphorin ,  dopa ,  分子生物学 ,  生化学 ,  薬理学 ,  神経生物学 ,  Molecular Biology ,  Biochemistry ,  Pharmacology ,  Neurobiology
Research theme for competitive and other funds  (40):
  • 2021 - 2024 The analysis for the circuits of L-DOPA-containing neurons in the central nervous system
  • 2019 - 2024 Novel biomarker research for schizophrenia
  • 2018 - 2021 ドーパ性神経伝達機構とそれに関わるトランスポーター分子の解析
  • 2016 - 2019 CRMP4 is involved in forming sex differences in the brain
  • 2015 - 2018 心血管系調節におけるドーパ神経伝達系の役割
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Papers (257):
  • Masami Arai, Etsuko Suzuki, Satoshi Kitamura, Momoyo Otaki, Kaori Kanai, Miwako Yamasaki, Masahiko Watanabe, Yuki Kambe, Koshi Murata, Yuuki Takada, et al. Enhancement of haloperidol-induced catalepsy by GPR143, an L-DOPA receptor, in striatal cholinergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024
  • Hiraku Uchimura, Kaori Kanai, Masami Arai, Miyu Inoue, Akitoyo Hishimoto, Daiki Masukawa, Yoshio Goshima. Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate. Journal of pharmacological sciences. 2023. 152. 3. 178-181
  • Daiki Masukawa, Satoshi Kitamura, Rei Tajika, Hiraku Uchimura, Masami Arai, Yuuki Takada, Tetsu Arisawa, Momoyo Otaki, Kaori Kanai, Kenta Kobayashi, et al. Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum. Journal of neurochemistry. 2023
  • Daiki Masukawa, Ryo Takahagi, Yuka Nakao, Yoshio Goshima. L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α1B Receptor at the Second Transmembrane Interface. Biological & pharmaceutical bulletin. 2023. 46. 7. 869-873
  • Ethiraj Ravindran, Nobuto Arashiki, Lena-Luise Becker, Kohtaro Takizawa, Jonathan Lévy, Thomas Rambaud, Konstantin L Makridis, Yoshio Goshima, Na Li, Maaike Vreeburg, et al. Monoallelic CRMP1 gene variants cause neurodevelopmental disorder. eLife. 2022. 11
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MISC (206):
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Patents (1):
  • Novel therapeutic intervention for blood pressure dysregulation
Books (11):
  • Semaphorin Signaling
    Humana 2017
  • Signal transduction key words
    Yodosha 2012
  • Cyclin Dependent Kinase 5 (Cdk5)
    Springer 2008
  • 神経伝達物質としてのドーパの神経生物学
    CRL 出版 2006
  • Neurobiology of DOPA as a Neurotransmitter.
    CRC Press 2006
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Lectures and oral presentations  (25):
  • ADRA1を介した血圧の昼夜変動の新たな制御機構 -L-ドーパは交感神経応答を制御する-
    (第54回高血圧関連疾患モデル学会 2018)
  • The role of L-DOPA as a neurotransmitter
    (18th World Congress of basic and clinical pharmacology 2018)
  • 双極性障害の翻訳後修飾異常
    (第53回先端医科学研究センター市民講座 2018)
  • ドーパ神経伝達物質仮説-その検証と創薬への道のり
    (第1回東京理科大学ー横浜市立大学合同シンポジウム 2017)
  • 認知症におけるバイオマーカーの開発
    (技術情報協会講習会 2017)
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Education (3):
  • - 1988 Yokohama City University Graduate School of Medicine
  • - 1982 Yokohama City University
  • - 1982 Yokohama City University Faculty of Medicine Graduate School of Medicine
Professional career (1):
  • 博士(医学) (横浜市立大学)
Work history (9):
  • 2020/04 - 現在 Yokohama City University
  • 1999/11 - 現在 Yokohama City University Graduate School of Medicine Molecular Pharmacology and Neurobiology Professor
  • 2014/04 - 2020/03 Yokohama City University
  • 2012/04 - Yokohama City University Graduate
  • 2008/08 - 2012/03 Yokohama City University Vice President
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Committee career (7):
  • 2018/03 - 現在 Japanese Pharmacological Society Director
  • 2018/03 - 現在 日本薬理学会 理事
  • 2016/04 - 現在 Yokohama City Environmental Evaluation Committee
  • 2016/04 - 現在 横浜市環境影響評価審査会委員
  • 2013/12 - 現在 Tokyo Metropolitan Institute of Medical Science Research Evaluation Committee
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Awards (2):
  • 1991 - 日本薬理学会学術奨励賞
  • 1991 - Award for young investigator
Association Membership(s) (10):
米国神経科学会 ,  日本神経化学会 ,  日本神経科学会 ,  日本薬理学会 ,  Society for Neuroscience ,  Japan Neurochemical Society ,  Japan Neuroscience Society ,  Japan Molecular Biology ,  Japan Biochemical Society ,  Japan Pharmacological Society
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