Research theme for competitive and other funds (22):
2020 - 2023 White melanosome for the DDS system
2013 - 2017 Elucidation of mechanism of neuropathic pain using acromelic acid A-induced allodynia model
2012 - 2015 アロディニアの発生機構解明に向けたカイノイド型分子プローブの創製
2012 - 2014 アロディニアの発生機構解明に向けたカイノイド型分子プローブの創製
2012 - 2014 アロディニアの発生機構解明に向けたカイノイド型分子プローブの創製
2010 - 2012 Treatment and measurement of neuropathic pain using acromelic acid analogues
2009 - 2011 Up-regulation of glial cell line-derived neurotrophic factor by newly synthesized cyclopentenone derivatives : Studies on cellular mechanisms in vitro and effectiveness in vivo
2008 - 2010 Synthesis of molecular probes for exploring the novel receptor involved in the allodynia induction
2006 - 2007 痛覚に関わるアクロメリン酸受容体探索プローブの創製
2006 - 2007 痛みのイメージングに向けたプローブ分子の設計
2005 - 2007 Synthesis and Application of Novel Cyclopentenone Molecular Probes with Neuroprotective Activity
2005 - 神経細胞保護作用を示す新規シクロペンテノン分子プローブの創製と活用
2005 - 2005 痛覚に関わるアクロメリン酸受容体探索プローブの創製
2004 - 2005 Studies of molecular mechanisms of rotenone-induced apoptosis and neurotrophic substances for dopaminergic neurons
2002 - 2004 新規エノン型プロスタグランジン分子プローブの創製と活用
2003 - 2004 Cloning of cDNA encoding a receptor to the glutamate derivative acromelic acid and the involvement in the pain induction system
2002 - 2003 Synthesis and application of novel enone-type prostaglandin probes
2001 - 2002 Development of novel anti-inflammatory drugs on the basis of prostaglandin A1 structure
1999 - 2001 Development of Anti-apoptoic Drugs for Neuronal Cells and Distribution Analysis in Brain
1996 - 1996 不斉合成手法に基づくプロスタグランジン分子リガンドの設計
1995 - 1995 金属手法に基づくトロンボキサン分子リガンドの設計
1985 - 1986 Development of Industrial Synthetic Process Toward Prostaglandins
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Papers (82):
Ayumi Sakurai, Kyoka Kawaguchi, Miyu Watanabe, Sayaka Okajima, Saho Furukawa, Kenichi Koga, Kentaro Oh-Hashi, Yoko Hirata, Kyoji Furuta, Hiroshi Takemori. Melanosomal localization is required for GIF-2115/2250 to inhibit melanogenesis in B16F10 melanoma cells. International Journal of Cosmetic Science. 2024
Saho Furukawa, Kyoka Kawaguchi, Kotomi Chikama, Ryohei Yamada, Yuji O. Kamatari, Lee Wah Lim, Hiroko Koyama, Yasuo Inoshima, Mitsushi J. Ikemoto, Saishi Yoshida, et al. Simple methods for measuring milk exosomes using fluorescent compound GIF-2250/2276. Biochemical and Biophysical Research Communications. 2024. 149505-149505
Yoko Hirata, Tomohiro Hashimoto, Kaori Ando, Yuji O Kamatari, Hiroshi Takemori, Kyoji Furuta. Structural features localizing the ferroptosis inhibitor GIF-2197-r to lysosomes. RSC advances. 2023. 13. 46. 32276-32281