Research theme for competitive and other funds (12):
2023 - 2026 疾患モデルを駆使した筋ジストロフィーの治療法開発
2021 - 2024 Molecular pathogenesis of brain malformations in de novo postzygotic mutations in the brain
2021 - 2024 Functional analysis of dystrophin in blood-brain barrier and its relevance to epilepsy
2018 - 2021 Elucidation of molecular pathomechanisms and the search for therapeutic targets of brain malformations, by employing cerebral organoids generated from patients-derived neural stem/progenitor cells
Hisashi Takahashi, Takahiro Fujimoto, Takeshi Yaoi, Shinji Fushiki, Kyoko Itoh. Leukemia inhibitory factor shortens primary cilia by upregulating C-C motif chemokine 2 in human neural stem/progenitor cells. Genes to cells : devoted to molecular & cellular mechanisms. 2023
Yoshihiro Taura, Takenori Tozawa, Takahiro Fujimoto, Eisuke Ichise, Tomohiro Chiyonobu, Kyoko Itoh, Tomoko Iehara. Myosin Va, a Novel Interaction Partner of STXBP1, Is Required to Transport Syntaxin1A to the Plasma Membrane. Neuroscience. 2023. 524. 256-268
Takahiro Fujimoto, Kirsten Stam, Takeshi Yaoi, Kenta Nakano, Tetsuya Arai, Tadashi Okamura, Kyoko Itoh. Dystrophin Short Product, Dp71, Interacts with AQP4 and Kir4.1 Channels in the Mouse Cerebellar Glial Cells in Contrast to Dp427 at Inhibitory Postsynapses in the Purkinje Neurons. Molecular neurobiology. 2023. 60. 7. 3664-3677
Kaori Kiso-Farnè, Takeshi Yaoi, Takahiro Fujimoto, Kyoko Itoh. Low Doses of Bisphenol A Disrupt Neuronal Differentiation of Human Neuronal Stem/Progenitor Cells. Acta histochemica et cytochemica. 2022. 55. 6. 193-202
Takahiro Fujimoto, Takeshi Yaoi, Kenta Nakano, Tetsuya Arai, Tadashi Okamura, Kyoko Itoh. Generation of dystrophin short product-specific tag-insertion mouse: distinct Dp71 glycoprotein complexes at inhibitory postsynapse and glia limitans. Cellular and molecular life sciences : CMLS. 2022. 79. 2. 109-109
Molecular analysis of a dystrophin gene product, Dp71, in the developing and adult mouse brains
(SCIENTIFIC SYMPOSIUM DOUBLE DEGREE MASTER PROGRAMME KYOTO PREFECTURAL UNIVERSITY OF MEDICINE AND MAASTRICHT UNIVERSITY 2021)
Dystrophin short isoform, Dp71, is regulated by phosphorylation and ubiquitin-proteasome system in neuronal cells
(11th FENS Forum of Neuroscience 2018)
Dystrophin short isoform, Dp71, is regulated by phosphorylation and ubiquitin-proteasome system in neuronal cells
(22nd Biennial Meeting of the International Society of Developmental Neuroscience 2018)