Shibata Naoki

シバタナオキ | Shibata Naoki

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.sci.u-hyogo.ac.jp/life/biophys1/index-j.html

Research field (1)： Structural biochemistry

Research keywords (7)：結晶化 , 構造生物学 , タンパク質 , X線結晶構造解析 , protein crystallization , structural studies , X-ray crystallography

Research theme for competitive and other funds (20)：

2021 - 2024 Structural basis of activation of a novel tumor progression signaling involving Wnt signaling proteins and supression by antibodies.
2019 - 2020 がん細胞増殖シグナルを活性化するタンパク質複合体の構造生物学
2018 - 2019 ポリオール廃液から有用アルコールを効率的に産出する発酵システムのための触媒の開発
2014 - 2019 Molecular design of nylon hydrolase and industrial application of the enzyme
2014 - 2017 Production of bifunctional recognition biomolecules for a novel crystallization method

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Papers (138)：

Naoki Shibata, Tetsuo Toraya. Structural basis for activation of cobalt-carbon bond and control of adenosyl radical in coenzyme B12 catalysis. Chembiochem : a European journal of chemical biology. 2023. e202300021
Seiji Negoro, Naoki Shibata, Dai-Ichiro Kato, Yusuke Tanaka, Kengo Yasuhira, Keisuke Nagai, Shohei Oshima, Yoko Furuno, Risa Yokoyama, Kaito Miyazaki, et al. X-ray crystallographic and mutational analysis of the NylC precursor: catalytic mechanism of autocleavage and substrate hydrolysis of nylon hydrolase. The FEBS journal. 2023
Naoki Shibata, Yoshiki Higuchi, Bernhard Kräutler, Tetsuo Toraya. Structural Insights into the Very Low Activity of the Homocoenzyme B12 Adenosylmethylcobalamin in Coenzyme B12 -Dependent Diol Dehydratase and Ethanolamine Ammonia-Lyase. Chemistry (Weinheim an der Bergstrasse, Germany). 2022. 28. 65. e202202196
Tetsuo Toraya, Takamasa Tobimatsu, Koichi Mori, Mamoru Yamanishi, Naoki Shibata. Coenzyme B12-dependent eliminases: Diol and glycerol dehydratases and ethanolamine ammonia-lyase. Methods in enzymology. 2022. 668. 181-242
Tetsuo Toraya, Takamasa Tobimatsu, Naoki Shibata, Koichi Mori. Reactivating chaperones for coenzyme B12-dependent diol and glycerol dehydratases and ethanolamine ammonia-lyase. Methods in enzymology. 2022. 668. 243-284

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MISC (65)：

柴田直樹, 樋口芳樹, 虎谷哲夫. O2により不活性化されたラジカルB12酵素ジオールデヒドラターゼの構造解析と補酵素分解物の同定. 第468回ビタミンB研究協議会. 2022
根来誠司, 武尾正弘, 柴田直樹, 樋口芳樹, 加藤太一郎, 重田育照. ナイロン分解酵素NylB の構造進化,触媒機構とアミド合成への応用. 月刊バイオインダストリー. 2019
Yamanaka Masaru, Hoshizumi Makoto, Nagao Satoshi, Nakayama Ryoko, Shibata Naoki, Higuchi Yoshiki, Hirota Shun. Formation and carbon monoxide-dependent dissociation of Allochromatium vinosum cytochrome c' oligomers using domain-swapped dimers. 2017
Kinugasa Ryo, Hada Keigo, Tanimoto Yuki, Takehara Ikki, Shibata Naoki, Kato Daiichiro, Takeo Masahiro, Negoro Seiji. 3P-046 Effect of amino acid substitution on the thermostability of nylon hydrolase. 2015. 67. 282-282
Y. Higuchi, M. Akter, C. Inoue, Y. Shomura, N. Shibata, K. Inaka, K. Kataoka, T. Sakurai, K. Komori. Preparation of single crystals of Multicopper oxidases for neutron diffraction study. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S324-S324

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Books (1)：

Professional career (1)：

Awards (1)：

Association Membership(s) (5)：

日本蛋白質科学会 , 日本放射光学会 , 日本生化学会 , 日本生物物理学会 , 日本結晶学会

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