Rchr
J-GLOBAL ID:200901040260557130   Update date: Jan. 30, 2024

Yoshikawa Yoko

ヨシカワ ヨウコ | Yoshikawa Yoko
Affiliation and department:
Research field  (4): Molecular biology ,  Cell biology ,  Tumor diagnostics and therapeutics ,  Medical biochemistry
Research keywords  (9): anti-tumor drug ,  tumor progression and metastasis ,  グアニンヌクレオチド交換因子 ,  Ras蛋白質 ,  rasがん遺伝子 ,  インシリコ創薬 ,  Raf蛋白質 ,  rafがん遺伝子 ,  低分子量G蛋白質
Research theme for competitive and other funds  (2):
  • 2022 - 2025 薬剤耐性がんでの新規RAS/RAF結合阻害剤の薬効評価および作用機序の解明
  • 2018 - 2021 Ras阻害剤による乳がん骨転移抑制機構の解明
Papers (15):
more...
MISC (2):
Patents (1):
  • Ras/Raf結合阻害化合物
Books (2):
  • ras がん遺伝子産物 Ras を分子標的としたがん治療薬開発の現状
    がん分子標的治療 2015
  • The Enzymes, Vol. 34, Inhibitors of the Ras superfamily G-proteins, Part B / Discovery of Small-Molecule Ras Inhibitors that Display Antitumor Activity by Interfering with Ras・GTP?Effector Interaction
    Elsevier Inc. 2013
Lectures and oral presentations  (24):
  • Role of Ras in triple-negative breast cancer
    (The 42nd Annual Meeting of the Molecular Biology Society of Japan 2019)
  • Ras inhibitors : Potential agents having both anti-proliferative and anti-metastatic properties
    (APMBMS 2019 Annual Meeting 2019)
  • Development of Anti-Cancer and Anti-Inflammatory Drugs Targeting Phospholipase Cε(ポスター発表)
    (2018 Keystone Symposia Conference 2018)
  • Development of Anti-Cancer and Anti-Inflammatory Drugs Targeting Phospholipase Cε
    (2018 Keystone Symposia Conference 2018)
  • Structural basis for the intramolecular interaction to assemble the c-Raf-1 recognition site in posttranslationally modified H-Ras•GTP
    (2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会 第90回日本生化学会大会) 2017)
more...
Education (3):
  • 2003 - 2007 Kobe University Graduate School of Medicine Molecular Biology
  • 1989 - 1991 Kob Univesity Graduate School of Science Biology
  • 1985 - 1989 Kobe Univerity Faculty of Science Biolgy
Professional career (2):
  • PhD. (Kobe University)
  • 博士(医学) (神戸大学)
Work history (4):
  • 2021/06 - 現在 Kobe University Graduate School of Science, Technology and Innovation Research Associate Professor
  • 2020/10 - 2021/05 Kobe University Office for Academic and Industrial Innovation Research Lecturer
  • 2016/04 - 2020/03 Kobe University Graduate School of Medicine Assistant Professor
  • 2011 - 2016/03 Kobe University Graduate School of Medicine Assistant Professor
Awards (4):
  • 2019/07 - Asia Pacific Society for Biology and Medical Sciences Outstanding research achivement and contribution to APSBMS Ras inhibitors: Potential agents having both anti-proliferative and anti-metastatic properties
  • 2013/10 - 神戸大学 新緑会 第1回新緑会ヤングインベスティゲーターアワード優秀賞 新規Ras機能阻害剤Kobe0065ファミリー化合物のがん転移抑制メカニズムの解析
  • 2008/02 - 神戸大学大学院医学系研究科 神戸大学大学院医学系研究科 優秀賞 低分子量GTP結合蛋白質Rasを標的とした新規抗癌剤の探索
  • 2006/12 - Kobe University 21th Century COE Program International Symposium The Best Presentation Award RA-GEF-2 mediates a crosstalk between small GTPases M-Ras and Rap1 to control integrin-dependent cell adhesion in lymphocytes
Association Membership(s) (2):
THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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