Research field (2)：
Nephrology
, Internal medicine - General
Research theme for competitive and other funds (31)：
2016 - 2019 Role of calcium sensing receptor in Kidney Type B Intercalated Cells
2016 - 2019 Investigation of the regulation system of erythropoiesis in the kidney by renin-angiotensin-aldosterone system
2014 - 2017 A role of kidney intercalated cells type B in regulatory transport of water and electrolytes
2015 - 2016 Aldosterone as an erythropoietic hormone: investigation of function and drug discovery
2012 - 2015 The mechanisms of regulation of nuclocytoplasmic transport of mineralocorticoid receptor by vasopressin V1a receptor.
2011 - 2012 The Investigation of the Mechanisms of the Regulation of RAS by Vasopresin V1a Receptor
2010 - 2011 The Investigation of the Mechanisms of the Regulation of RAS by Vasopresin V1a Receptor
2009 - 2011 Novel strategy for development of suppressive drugs for kidney disease based on inhibition of metabolic production of uremic toxins
2009 - 2011 The role of vasopressin V1a receptor in diabetic nephropathy and the invention of new therapy.
2007 - 2008 The investigation of the role of interaction of two types of antidiuretic hormone receptors for diuresis and the invention of the new therapy for renal edema.
2005 - 2008 Strategy for protection of kidney injury based on functioal relation betwee renal specific stress response mechanisms and xenobiotic detoxication systems
2006 - 2007 糖尿病性腎症の糸球体上皮細胞(足細胞)障害におけるGSK-3Βの役割の検討
2005 - 2006 Functional analysis of antidiuretic hormone receptor using V1a knockout mice and invention of new diuretics.
2004 - 2005 The role of GSK-3 dependent transcriptional factor on glomerulo injury
2003 - 2004 The investigation of the mechanisms and therapy of the abnormality in antidiuretic hormone action in patients with chronic renal failure
2001 - 2002 The effect of interstitial osmolarity in juxta-glomerular apparatus on macula densa cells and cloning of mammalian osmosensor
2001 - 2002 Regulation of diuresis by 2 types of antidiuretic hormone receptor in chronic renal failure and therapeutic investigation of edema
1999 - 2000 Role of renal arginase in acute renal failure
1999 - 2000 プロスタシンの増殖作用の研究および早期腫瘍マーカーとしての有用性の研究
1998 - 2000 Regulation of NO synthesis by the urea cycle enzymes
1998 - 1999 The study on molecular biological mechanisms and therapy of sodiam and acid disturbance in renal failure
1997 - 1998 Prevention of acute renal failure by anti-endothelin converting enzyme.
1997 - 1998 Role of endothelin converting enzyme in essential hypertension
1997 - 1997 新しいGTP結合蛋白(G_<13>)をかいしたイオンチャネル活性機序の解明
1996 - 1997 Gene therapy for acute renal failure
1996 - 1997 The investigation of molecular biological mechanisms and therapy of refractory renal edema.
1994 - 1995 The investigation of the mechanisms and the rapy of renal edema from the acpect of cell porality.
1993 - 1995 Elucidation of the mechanism of essential hypertension making a transgenic mice made by putative kallikrein binding protein
1992 - 1994 Elucidation of mechanism of acute renal failure by use molecular biological techniques
1992 - 1993 Role and therapy of renal medullary dysfunction as a risk factor for chronic renal failure
Yukiko Yasuoka, Yuichiro Izumi, Takashi Fukuyama, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Masayoshi Nanami, Yoshitaka Shimada, Yasushi Nagaba, et al. Tubular Endogenous Erythropoietin Protects Renal Function against Ischemic Reperfusion Injury. International journal of molecular sciences. 2024. 25. 2
Makoto Ono, Yuichiro Izumi, Kosuke Maruyama, Yukiko Yasuoka, Akiko Hiramatsu, Jose Aramburu, Cristina López-Rodríguez, Hiroshi Nonoguchi, Yutaka Kakizoe, Masataka Adachi, et al. Characterization of gene expression in the kidney of renal tubular cell-specific NFAT5 knockout mice. American journal of physiology. Renal physiology. 2023
Yukiko Yasuoka, Yuichiro Izumi, Jeff M Sands, Katsumasa Kawahara, Hiroshi Nonoguchi. Progress in the Detection of Erythropoietin in Blood, Urine, and Tissue. Molecules (Basel, Switzerland). 2023. 28. 11
Yukiko Yasuoka, Yuichiro Izumi, Takashi Fukuyama, Haruki Omiya, Truyen D. Pham, Hideki Inoue, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, et al. Effects of Roxadustat on Erythropoietin Production in the Rat Body. Molecules. 2022. 27. 3. 1119-1119
Akiko Hiramatsu, Yuichiro Izumi, Koji Eguchi, Naomi Matsuo, Qinyuan Deng, Hideki Inoue, Yushi Nakayama, Hiroshi Nonoguchi, Jose Aramburu, Cristina López-Rodríguez, et al. Salt-Sensitive Hypertension of the Renal Tubular Cell-Specific NFAT5 (Nuclear Factor of Activated T-Cells 5) Knockout Mice. Hypertension (Dallas, Tex. : 1979). 2021. 78. 5. HYPERTENSIONAHA12117435-1346
1983 - 1984 The University of Tokyo School of Medicine Department of Pharmcology
1980 - 1982 Tokyo Meical & Dental University Faculy of Medicine Second Department of Internal Medicine
1973 - 1979 Tokyo Medical and Dental University Faculty of Medicine
Professional career (1)：
Doctor of Medicine
Work history (15)：
2020/04 - 現在 Kitasato University Medical Center General Internal Medicine Doctor
2016/04 - 2020/03 Kitasato University Medical Center General Internal Medicine Chief
2012/05 - 2016/03 Kitasato University Kitasato Institutes Medical Center Hospital Genral Internal Medicine Chief
2008/04 - 2012/03 Hyogo College of Medicine Internal Medicine Section of Kidney and Dialysis Associate Professor
2003/04 - 2008/03 Kumamoto University Graduate School of Medicine Departmen of Kidney Associate Professor
1995/08 - 2003/03 Kumamoto University Medical Hospital Third Department of Interna Medicine Associate Professor
1995/04 - 1995/07 Kumamoto UniversityMedical Hospital Third Department of Internal Medicine Assistant Professor
1989/03 - 1995/03 Tokyo Meical & Dental University Hospital Blood Transfusion Section Assistant Professor
1988/06 - 1989/02 Tokyo Meical & Dental University Hospital Second Departemnt of Internal Medicine Doctor
1988/01 - 1988/02 Sashima Kyodo Hospital Internal Medicine Chief Doctur
1985/01 - 1987/12 National Institutes of Health (USA) National Heart, Lung and Blood Institute KIdney Section Research Fellow
1984/08 - 1984/12 Social Insurance Mishima Hospital Internal Medicine Chief Doctor
1982/06 - 1984/07 Tokyo Meical & Dental University Hospital Wecond Department of Internal Medicine Doctor
1980/06 - 1982/05 Toride Kyodo Hospital Department of Internal Medicine Doctor
1979/04 - 1980/05 Tokyo Medical and Dental University University Hospital Second Department of Internal Medicine Medical Intern
Show all
Committee career (3)：
2012/04 - 2018/03 Japanese Society of Nephrology Corporate councilor
2010/06 - 2014/03 Japanese Society for Dialysiis Therapy councilor
1995/05 - 2012/04 日本腎臓学会 学術評議員
Awards (2)：
1998 - 持田医学薬学研究財団研究奨励賞
1992 - 東京医科歯科大学医科同窓会研究奨励賞
Association Membership(s) (5)：
American Society of Nephrology
, The Japanese Society of Hypertension
, Japanese Society for Dialysis Therapy
, Japanese Society of Nephrology
, The Japanese Sociey of Internal Medicine
