Rchr
J-GLOBAL ID：200901040560549121
Update date: Jun. 08, 2020
Tanabe Hiroki
タナベ ヒロキ | Tanabe Hiroki
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Affiliation and department：
Asahikawa Medical University School of Medicine, Medical Course
About Asahikawa Medical University School of Medicine, Medical Course
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Research field (2)：
Gastroenterology
, Immunology
Research keywords (6)：
抗菌ペプチド
, Paneth細胞
, ヘリコバクター
, 胃癌
, ディフェンシン
, 自然免疫
Research theme for competitive and other funds (2)：
消化管免疫と炎症から発癌への機構の解明
消化器疾患における自然免疫の役割の解析とその治療への応用
MISC (6)：
Hiroki Tanabe, Tomonobu Sato, Jiro Watari, Atsuo Maemoto, Mikihiko Fijiya, Toru Kono, Toshifumi Ashida, Tokiyoshi Ayabe, Yutaka Kohgo. Functional role of metaplastic paneth cell defensins in Helicobacter pylori-infected stomach. HELICOBACTER. 2008. 13. 5. 370-379
Hiroki Tanabe, Tokiyoshi Ayabe, Atsuo Maemoto, Chisato Ishikawa, Yuhei Inaba, Ryu Sato, Kentaro Moriichi, Kotaro Okamoto, Jiro Watari, Toru Kono, et al. Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007. 358. 1. 349-355
H Tanabe, T Ayabe, B Bainbridge, T Guina, RK Ernst, RP Darveau, SI Miller, AJ Ouellette. Mouse Paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria. INFECTION AND IMMUNITY. 2005. 73. 4. 2312-2320
H Tanabe, AJ Ouellette, MJ Cocco, WE Robinson. Differential effects on human immunodeficiency virus type 1 replication by alpha-defensins with comparable bactericidal activities. JOURNAL OF VIROLOGY. 2004. 78. 21. 11622-11631
H Tanabe, XQ Qu, CS Weeks, JE Cummings, S Kolusheva, KB Walsh, R Jelinek, TK Vanderlick, ME Selsted, AJ Ouellette. Structure-activity determinants in Paneth cell alpha-defensins - Loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions. JOURNAL OF BIOLOGICAL CHEMISTRY. 2004. 279. 12. 11976-11983
ｍore...
Professional career (1)：
医学 (旭川医科大学大学院)
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