Rchr
J-GLOBAL ID:200901040597515081
Update date: May. 02, 2020
Niizuma Hideko
ニイヅマ ヒデコ | Niizuma Hideko
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Research field (1):
Pharmaceuticals - chemistry and drug development
Research keywords (2):
ペプチド合成
, peptide synthesis
Research theme for competitive and other funds (2):
オピオイドペプチドの合成と構造活性相関
Synthesis and comformation-activity relationship of opioid peptide analogs
MISC (4):
A Ambo, H Niizuma, A Sasaki, H Kohara, Y Sasaki. Dermorphin tetrapeptide analogues with 2',6'-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high mu opioid receptor binding and biological activities. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2003. 13. 7. 1269-1272
Endomorphin 2 analogues containing Dmp residue as an aromatic amino acid surrogate with high mu-opioid receptor affinity and selectivity. Bioorganic & Medicinal Chemistry. 2003. 11 , 675-678
A Ambo, H Murase, H Niizuma, H Ouchi, Y Yamamoto, Y Sasaki. Dermorphin and deltorphin heptapeptide analogues: Replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2002. 12. 6. 879-881
A Ambo, H Murase, H Niizuma, H Ouchi, Y Yamamoto, Y Sasaki. Dermorphin and deltorphin heptapeptide analogues: Replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2002. 12. 6. 879-881
Education (2):
- 2001 東北薬科大学 薬学部 薬学科
- 2001 Tohoku Pharmaceutical University Faculty of Pharmaceutical Science
Work history (1):
Tohoku Pharmaceutical University Faculty of Pharmaceutical Sciences, Department of Hygienic Pharmacentical Science
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