Abe Keietsu

アベケイエツ | Abe Keietsu

Affiliation and department：
Job title： Professor
Other affiliations (1)：

Tohoku University New Industry Creation Hatchery Center

Homepage URL (2)： https://sites.google.com/view/tohoku-applied-microbio , https://sites.google.com/view/tohoku-applied-microbio/english

Research field (5)： Applied biochemistry , Green/sustainable/environmental chemistry , Applied biofunctional and bioprocess engineering , Applied molecular and cellular biology , Applied microbiology

Research keywords (1)： Applied Microbiology

Research theme for competitive and other funds (22)：

2003 - 現在 Conversion of Macromolecules from Agribio Industry
2002 - 現在 Biological recycle of biodegradable plastics
2000 - 現在 Cell Biology of Signal Transduction Pathways in Fungi
1999 - 現在 Study on Proton Motive Force Generation Coupled with Decarboxylation
2020 - 2023 Molecular mechanism of hyphal aggregation evoked by cell-surface polysaccharides in filamentous fungi.

2017 - 2020 Molecular mechanism of fungal bio-surfactant protein hydrophobin involving in biological functions of filamentous fungi at interfaces

2016 - 2019 Improvement of biocontrol activity in industrial-scale composters and screening of microorganisms showing biocontrol activities from the composters

2015 - 2018 Study of allosteric regulation of solute transporter by a second-messenger and its structural analysis.

2015 - 2018 Development of stealth-nanoparticles avoiding animal immune system that mimics the cell surface of filamentous fungi.

2014 - 2018 Hyphal adhesion and sexual development via cell wall polysaccharide controlled by MAP kinase cascades

2015 - 2017 Development of magnetite nanoparticles targeting cancer tissues by antisense peptides

2014 - 2017 Development of magnetite nanoparticle with stealth and active targeting function

2012 - 2014 Development of immune-response free nano-particles using fungal biosurfactant protein

2011 - 2011 Development of a novel MRI contrast medium toward detection of hypoxic lesions and quantification of partial oxygen pressure

2010 - 2011 Development of transporter-control technology for fermentatio

2008 - 2010 Comprehensive study of fungal biosurfactant proteins that recruit polymer-degrading enzymes onto solid polymer-surfaces

2005 - 2009 Molecular mechanisms for production of useful proteins in Aspergillus fungi based on genomic information

2006 - 2007 Recruitment of plastic-degrading enzymes onto the surface of plastics via fungal hydrophobin RolA

2006 - 2007 Host for highly efficient gene targeting in filamentous fungi

2003 - 2005 ANALYSIS OF TRANSCRITIONAL REGULATORY NETWORKS IN ASPERGILLUS ORYZAE USING REGULATORY MUTANT LIBRARY AND DNA MICROARRAY

2004 - 2004 アスペルギルス属カビの生育環境特異的な遺伝子発現制御の分子機構

2003 - 2003 アスペルギルス属カビの生育環境特異的な遺伝子発現制御の分子機構

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Papers (130)：

Ken Miyazawa, Takashi Umeyama, Shogo Takatsuka, Yasunori Muraosa, Yasutaka Hoshino, Shigekazu Yano, Keietsu Abe, Yoshitsugu Miyazaki. Real-time monitoring of mycelial growth in liquid culture using hyphal dispersion mutant of Aspergillus fumigatus. Medical Mycology. 2024
Development of hyphal-dispersion koji mold and its application to fermentation. Agricultural Biotechnology. 2023. 7. 8. 687-692
Nao Takahashi, Yuki Terauchi, Takumi Tanaka, Akira Yoshimi, Hiroshi Yabu, Keietsu Abe*. Involvement of ionic interactions in self-assembly and resultant rodlet formation of class I hydrophobin RolA from Aspergillus oryzae. Bioscience, biotechnology, and biochemistry. 2023. 87. 8. 857-864
Shigenari Yamaguchi, Tomonori Fujioka, Akira Yoshimi, Toshitaka Kumagai, Maiko Umemura, Keietsu Abe, Masayuki Machida a, Kiyoshi Kawai. Discovery of a gene cluster for the biosynthesis of novel cyclic peptide compound, KK-1, in Curvularia clavata. Frontiers in Fungal Biology. 2023. 3
Ami Koizumi, Ken Miyazawa, Makoto Ogata, Yuzuru Takahashi, Shigekazu Yano, Akira Yoshimi, Motoaki Sano, Masafumi Hidaka, Takanori Nihira, Hiroyuki Nakai, et al. Cleavage of α-1,4-Glycosidic Linkages by the Glycosylphosphatidylinositol-Anchored α-Amylase AgtA Decreases the Molecular Weight of Cell Wall α-1,3-Glucan in Aspergillus oryzae. Frontiers in Fungal Biology. 2023. 3. 10.3389/ffunb.2022.1061841

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MISC (217)：

井田大輝, 寺内裕貴, 田中拓未, 吉見啓, 宮澤拳, 三ツ石方也, 藪浩, 藪浩, 阿部敬悦. Analysis of Self-Assembly Mechanism and Surface Activity of Hydrophobin RolA, a Surfactant Protein from A. oryzae. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
井田大輝, 寺内裕貴, 田中拓未, 吉見啓, 三ツ石方也, 藪浩, 藪浩, 阿部敬悦. Analysis of Self-Assembly Mechanism and Interface Activity of Surface-Active Protein RolA from Aspergillus oryzae. 日本生物工学会大会講演要旨集. 2022. 74th
高橋尚央, 寺内裕貴, 田中拓未, 吉見啓, 藪浩, 藪浩, 阿部敬悦. Positive amino acid residues located in the N-terminal region of fungal hydrophobin RolA is involved in rod-like structure formation. 日本生物工学会大会講演要旨集. 2022. 74th
名和義順, 河内護之, 中沢威人, 坂本正弘, 阿部敬悦, 田中千尋, 吉見啓, 本田与一. Identification and functional analysis of α-1,3-glucan synthase gene in Pleurotus ostreatus. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
高橋尚央, 寺内裕貴, 田中拓未, 吉見啓, 藪浩, 藪浩, 阿部敬悦. 麹菌由来hydrophobin RolAが形成するβ-amyloid様棒状構造の伸長機構解析. 日本農芸化学会東北支部大会プログラム・講演要旨集. 2022. 2022

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Patents (22)：

麹菌の細胞壁変異株の選抜方法、当該細胞壁変異株、当該細胞壁変異株を用いた米製品およびその製造方法
糸状菌の高密度培養株を用いた有用物質の生産方法
環状ペプチド化合物合成関連遺伝子、これを用いた環状ペプチド化合物の製造法及びこれを有する形質転換体
EBD及びHKD含有融合ペプチド及び当該ペプチドを発現する形質転換体
麹菌由来ホスホリパーゼA2

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Books (9)：

「酵母菌・麹菌・乳酸菌の産業応用展開」五味勝也, 阿部敬悦監修バイオテクノロジーシリーズ
CMC出版 2018
分子麹菌学
日本醸造協会 2012
リサイクル・廃棄物事典
産業調査会 2012
リサイクル・廃棄物事典
産業調査会 2012
農学・生命科学のための学術情報リテラシー
朝倉書店 2011

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Lectures and oral presentations (246)：

新規 PKC 阻害剤Z-705の糸状菌特異性の評価および既存 PKC 阻害剤との効果比較
(日本農芸化学会2018年度大会 2018)
麹菌由来界面活性タンパク質 hydrophobin RolA の液中における単量体・多量体の性質と挙動
(日本農芸化学会2018年度大会 2018)
産業用糸状菌Aspergillus oryzaeのGPI型糖転移酵素AgtAの生物学的機能解析
(日本農芸化学会2018年度大会 2018)
Aspergillus nidulansの2種のα-1,3-グルカン合成酵素による産生多糖の化学構造解析
(日本生物工学会北日本支部シンポジウム2017福島 2017)
大腸菌Ala排出機能欠損株を用いた乳酸菌 Tetragenococcus halophilus 由来Aspartate : Alanine 交換輸送体 AspT の輸送評価系の構築
(日本生物工学会北日本シンポジウム2017福島 2017)

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Education (1)：

- 1981 Tohoku University Faculty of Agriculture 農芸化学

Professional career (1)：

Ph.D. (The University of Tokyo)

Work history (6)：

2009/07 - 現在 Tohoku University Graduate School of Agricultural Science
2019/04 - 2022/03 Tohoku University Graduate School of Agricultural Science Dean
2017/04 - 2019/03 Tohoku University New Industry Creation Hatchery Center
1999/06 - 2009/06 Tohoku University Graduate School of Agricultural Science
1981/04 - 1999/05 キッコーマン株式会社研究本部研究員

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Committee career (12)：

2019/05 - 2021/04 日本農芸化学会副会長
2015/05 - 2019/04 日本農芸化学会財務担当理事
2013/04 - 2016/03 「沖縄県ー知的クラスター形成に向けた研究拠点構築事業」評価委員会評価委員
2011/04 - 2015/03 日本農芸化学会和文誌編集委員
2011/09 - 2013/08 日本乳酸菌学会学会英文誌editor

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Awards (5)：

2022/03 - 日本農芸化学会日本農芸化学会功績賞醸造微生物の細胞表層機能に関する生化学的研究とその産業応用
2018/03 - 日本農芸化学会日本農芸化学会英文誌BBB論文賞 Escherichia coli yjjPB genes encode a succinate transporter important for succinate production.
2008/03 - 日本農芸化学会日本農芸化学会英文誌BBB論文賞 The β-1,3-Exoglucanase Gene exgA (exg1) of Aspergillus oryzae is required to catabolise the Extracellular Glucan and induced in Growth on Solid Surface.
2007/09 - 日本醸造家王会日本醸造協会特別表彰麹菌ゲノム解析
2003/09/09 - 日本醸造協会日本醸造協会技術賞麹菌のEST解析

Association Membership(s) (4)：

日本生物工学会 , 日本乳酸菌学会 , 日本農芸化学会 , アメリカ微生物学会(American Society for Microbiology)

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