Rchr
J-GLOBAL ID:200901040945042532   Update date: Jul. 31, 2023

Miyata Yoshihiko

ミヤタ ヨシヒコ | Miyata Yoshihiko
Affiliation and department:
Job title: Assistant Professor
Research field  (3): Cell biology ,  Molecular biology ,  Functional biochemistry
Research keywords  (13): DYRK ,  Cdc37 ,  CK2 ,  Hsp90 ,  シグナル伝達 ,  分子シャペロン ,  キナーゼ ,  DYRK ,  Cdc37 ,  CK2 ,  Signal transduction ,  Molecular Chaperone ,  Kinase
Research theme for competitive and other funds  (33):
  • 2018 - 2023 Analysis of physiological function of Down syndrome-associated DYRK1A-WDR68 complex.
  • 2013 - 2016 Analysis of physiological function of the complex between the Down syndrome kinase DYRK1A and WDR68.
  • 2012 - 2014 Analysis of the recognition mechanism of the intrinsically disordered region of Cdc37 to signaling protein kinases.
  • 2011 - 2013 Mechanism of the interaction of the Tau and FKBP52 proteins; applications to Tauopathies.
  • 2011 - 2012 Analysis of cellular function of WDR68, a specific binding partner for Down-syndrome associated DYRK1A.
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Papers (77):
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MISC (3):
Books (11):
  • CK2 inhibitors and the DYRK family protein kinases.
    “Protein Kinase CK2 Cellular Function in Normal and Disease States”, ed. K. Ahmed, O. Issinger, and R. Szyska, Advances in Biochemistry in Health and Disease, Springer International Publishing Switzerland, Vol. 12. 2015
  • The pivotal role of CK2 in the kinome-targeting Hsp90 chaperone machinery.
    “The Wiley-IUBMB Series on Biochemistry and Molecular Biology: Protein Kinase CK2”, ed. L.A.Pinna and J. Jeffryes, Wiley-Blackwell Publishing 2013
  • シグナル伝達の原理と多様性. 「医学のための細胞生物学」
    南山堂 2009 ISBN:4525131217
  • 分子生物学・免疫学キ-ワ-ド辞典 第二版
    医学書院 2003
  • 熱ショックタンパク質(HSP90・GRP94).
    廣川タンパク質化学 第六巻「細胞骨格と筋肉のタンパク質」、廣川書店(東京),139-145 1997
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Lectures and oral presentations  (98):
  • Identification of FAM53C as a novel regulatory binding protein of DYRK1A
    (2nd International Meeting on DYRK1A, related kinases and human disease 2022)
  • Functional Regulation of Down Syndrome and Autism Spectrum Disorder-related DYRK family protein kinases
    (2019)
  • Hsp90 molecular chaperone, signaling protein kinases, and cancer
    (Seminar at Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg (Strasbourg, France) 2018)
  • Functional regulation of DYRK1A, a kinase intimately involved in Down syndrome and autism spectrum disorder, by cellular binding partners
    (Seminar at Institut de Génétique et de Biologie Moléculaire et Cellulaire (Illkirch, France) 2018)
  • ダウン症関連キナーゼDYRKファミリーの細胞内結合分子シャペロンによる機能制御
    (埼玉大学 分子生物学科セミナー (埼玉) 2017)
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Education (6):
  • - 1992 The University of Tokyo
  • - 1992 The University of Tokyo Graduate School, Division of Science Cell & Molecular Biochemistry
  • - 1988 The University of Tokyo
  • - 1988 The University of Tokyo Graduate School, Division of Science
  • - 1986 The University of Tokyo Faculty of Science
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Professional career (1):
  • Ph. D. (The University of Tokyo)
Work history (20):
  • 2007 - 現在 Kyoto University Graduate School of Biostudies, Division of Integrated Life Science
  • 2007 - 現在 Associate Professor, Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University.
  • 1999 - 2007 Kyoto University Graduate School of Biostudies, Division of Integrated Life Science
  • 1999 - 2007 Research Associate, Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University.
  • 2005 - 神戸大学 大学院医学系研究科 非常勤講師 兼任
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Association Membership(s) (2):
日本生化学会 ,  The Japanese Biochemistry Society.
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