Rchr
J-GLOBAL ID：200901041019892642   Update date: Apr. 17, 2024

Nakahama Ken'ichi

ナカハマ ケンイチ | Nakahama Ken'ichi
Affiliation and department：
Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Cellular Physiological Chemistry

About Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Cellular Physiological Chemistry


Job title： Associate Professor
Research field  (1)： Oral medicine
Research keywords  (7)： endothelial cell ,  osteocyte ,  osteoblast ,  osteoclast ,  cellular communication ,  gap junction ,  connexin
Research theme for competitive and other funds  (23)：
  • 2022 - 2025 身体不活動による骨量低下の分子機序解明と骨量低下抑制法の確立
  • 2022 - 2024 Analysis of heterogenous character of neural crest-derived osteoblasts
  • 2019 - 2022 Mechanism for suppression of osteoclastic bone resorption by mechanical stress in bone
  • 2018 - 2020 炎症性疾患におけるCX3CL1を介した破骨細胞前駆細胞の骨芽細胞層通過機構の解明
  • 2018 - 2020 骨形成転換機構に関与する破骨細胞由来因子の同定および個体での役割解明
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Papers (75)：
  • Worachat Namangkalakul, Shigenori Nagai, Chengxue Jin, Ken-Ichi Nakahama, Yuki Yoshimoto, Satoshi Ueha, Kazunari Akiyoshi, Kouji Matsushima, Tomoki Nakashima, Masaki Takechi, et al. Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization. Journal of tissue engineering. 2023. 14. 20417314231187960-20417314231187960
  • Atsuko Fujioka, Mamoru Nagano, Keisuke Ikegami, Koh-Hei Masumoto, Tomoko Yoshikawa, Satoshi Koinuma, Ken-Ichi Nakahama, Yasufumi Shigeyoshi. Circadian expression and specific localization of synaptotagmin17 in the suprachiasmatic nucleus, the master circadian oscillator in mammals. Brain research. 2022. 1798. 148129-148129
  • Shiho Hidaka, Yuki Mouri, Masako Akiyama, Naoyuki Miyasaka, Ken-Ichi Nakahama. GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis. Prostaglandins, leukotrienes, and essential fatty acids. 2022. 182. 102457-102457
  • Risa Kawatsura, Yusuke Hara, Masako Akiyama, Noriko Tachikawa, Ken-Ichi Nakahama. Gap junctional intercellular communication attenuates osteoclastogenesis induced by activated osteoblasts. Biochemical and biophysical research communications. 2022. 597. 71-76
  • Shuhei Fukuda, Masako Akiyama, Yuki Niki, Risa Kawatsura, Hiroyuki Harada, Ken-Ichi Nakahama. Inhibitory effects of miRNAs in astrocytes on C6 glioma progression via connexin 43. Molecular and cellular biochemistry. 2021. 476. 7. 2623-2632
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MISC (17)：
  • 沖藤 明日香, 中浜 健一, 細道 純, 舌野 知佐, 臼見 莉沙, 清水 康広, 石田 雄之, 金香 佐和, 森田 育男, 小野 卓史. 骨芽細胞の破骨細胞支持能の獲得におけるプロトンセンサーGPR4の関与. 日本矯正歯科学会大会プログラム・抄録集. 2014. 73回. 220-220
  • 藤岡厚子, 長野護, 堀内喜高, 升本宏平, 中浜健一, 重吉康史. Synaptotagmin17の概日リズム. 日本組織細胞化学会総会・学術集会講演プログラム・予稿集. 2011. 52nd
  • 藤岡 厚子, 長野 護, 堀内 喜高, 升本 宏平, 中浜 健一, 重吉 康史. P-11 Synaptotagmin 17の概日リズム(1:脳・神経,ポスター,第52回日本組織細胞化学会総会・学術集会). 日本組織細胞化学会総会プログラムおよび抄録集. 2011. 52. 64-64
  • Hitoshi Ozawa, Takeshi Suzuki, Ken-ichi Nakahama, Ikuo Morita. Intercellular cAMP movement between different cell types via GJIC. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 111P-111P
  • Rajib Bhattacharjee, Makoto Kaneda, Ken-ichi Nakahama, Ikuo Morita. THE STEADY-STATE EXPRESSION LEVEL OF CONNEXIN43 IS MAINTAINED BY THE PI3K/AKT PATHWAY. JOURNAL OF VASCULAR RESEARCH. 2009. 46. 84-84
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Lectures and oral presentations  (44)：
  • Mechanical cues of polyrotaxanes control osteogenic differentiation for adjunct treatment of craniosynostosis
    (The 43rd Annual Meeting of the Molecular Biology Society of Japan 2020)
  • The Role of G-protein coupled receptor 110 (GPR110) in osteoclast differentiation.
    (MBSJ 2019 2019)
  • VD3/cAMP-mediated transcriptional regulation of osteopontin in osteoblasts
    (MBSJ 2019 2019)
  • Impact of GPR68 on cAMP signaling in osteoblasts
    (2019)
  • ケミカルバイオロジーからアプローチしたTAZの新しい制御機構の解析
    (第41回分子生物学会年会 2018)
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Education (2)：
  • 1984 - 1986 Yamaguchi University Graduate School, Division of Natural Science
  • 1980 - 1984 Yamaguchi University Faculty of Science
Professional career (1)：
  • 博士(学術) (東京医科歯科大学)
Work history (11)：
  • 2020/09/01 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Cellular Physiological Chemistry Associate Professor
  • 2018/04/01 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Cellular Physiological Chemistry Associate Professor
  • 2018/04/01 - 2020/08/31 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Cellular Physiological Chemistry Associate Professor
  • 2004/04/01 - 2020/08/31 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Cellular Physiological Chemistry
  • 2002/04/01 - 2020/08/31 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Cellular Physiological Chemistry Junior Associate Professor
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