Rchr
J-GLOBAL ID:200901041549747481   Update date: Apr. 23, 2024

Ito Takuhiro

イトウ タクヒロ | Ito Takuhiro
Affiliation and department:
Job title: Unit Leader
Research field  (1): Structural biochemistry
Research keywords  (11): Electron Microscopy ,  X線結晶構造解析 ,  tRNA ,  核酸 ,  修飾塩基 ,  翻訳 ,  翻訳開始因子 ,  リボソーム ,  RNA ,  タンパク質 ,  立体構造
Research theme for competitive and other funds  (12):
  • 2021 - 2026 Structural Analysis of Non Domain Biopolymer
  • 2021 - 2026 Management of non-domain biopolymer research group
  • 2022 - 2025 Tissue-specific regulation of translation initiation mediated by ribosome heterogeneity
  • 2019 - 2022 Structural basis of traslation regulation by dynamic interactions between the complexes
  • 2017 - 2019 ウイルスが引き起こす非標準的な翻訳機構の構造基盤
Show all
Papers (59):
  • Mayuki Tanaka, Takeshi Yokoyama, Hironori Saito, Madoka Nishimoto, Kengo Tsuda, Naoyuki Sotta, Hideki Shigematsu, Mikako Shirouzu, Shintaro Iwasaki, Takuhiro Ito, et al. Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Nature Chemical Biology. 2024
  • Kazuhiro Kashiwagi, Takuhiro Ito. Switching on stress. Nature Chemical Biology. 2023
  • Shintaro Iwasaki, Hironori Saito, Yuma Handa, Mingming Chen, Tilman Schneider-Poetsch, Yuichi Shichino, Mari Takahashi, Daniel Romo, Minoru Yoshida, Alois Furstner, et al. Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs. 2023
  • Mingming Chen, Naoyoshi Kumakura, Ryan Muller, Yuichi Shichino, Madoka Nishimoto, Mari Mito, Pamela Gan, Nicholas T. Ingolia, Ken Shirasu, Takuhiro Ito, et al. A parasitic fungus employs mutated eIF4A to survive on rocaglate-synthesizing Aglaia plants. 2022
  • 半田 佑磨, 川嶋 裕介, 古石 誉之, 米持 悦生, 伊藤 拓宏, 斉藤 大寛, 岩崎 信太朗, 加藤 幸一郎, 渡邉 千鶴, 本間 光貴, et al. eIF4A阻害剤のRNA配列特異性に対する動的FMO解析. 日本薬学会年会要旨集. 2022. 142年会. 27C-am11S
more...
MISC (9):
  • 柏木 一宏, 伊藤 拓宏. 統合的ストレス応答における翻訳制御の構造生物学-Structural biology of translation regulation in the integrated stress response-特集 翻訳制御の最前線. 細胞. 2022. 54. 12. 688-691
  • HANDA Yuma, KAWASHIMA Yusuke, FURUISHI Takayuki, YONEMOCHI Etsuo, ITO Takuhiro, SAITO Hironori, SAITO Hironori, IWASAKI Shintaro, IWASAKI Shintaro, WATANABE Chiduru, et al. Dynamic FMO analysis for RNA sequence specificity in inhibitor recognition of translation initiation factor complex. CBI学会大会. 2021. 2021 (CD-ROM)
  • 池内与志穂, 岩崎信太郎, 伊藤拓宏. eIF2B結合性ウイルスタンパク質NSsによる統合的ストレス応答抑制. 日本生化学会大会(Web). 2021. 94th
  • 岩崎わかな, 高橋真梨, INGOLIA Nicholas T, 岩崎信太郎, 伊藤拓宏. Rocaglamide Aによる配列特異的な翻訳阻害の構造基盤. 日本RNA学会年会要旨集. 2018. 20th. 34
  • 松田貴意, 伊藤拓宏, 池田眞理子, 大沢登, 竹本千重, 新野睦子, 横山茂之, 黒澤良和, 白水美香子. 抗体抗原複合体の立体構造解析のための低分子化抗体の無細胞タンパク質合成. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
more...
Professional career (1):
  • Ph.D. (The University of Tokyo)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page