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J-GLOBAL ID:200901041949734885   Update date: Apr. 07, 2024

Yoshimura Akihiko

ヨシムラ アキヒコ | Yoshimura Akihiko
Affiliation and department:
Homepage URL  (1): http://new2.immunoreg.jp/
Research field  (1): Immunology
Research keywords  (4): 病態医科学 ,  biochemistry ,  免疫学 ,  Immunology
Research theme for competitive and other funds  (61):
  • 2021 - 2026 Brain inflammation and repair mechanism by adaptive immunity
  • 2019 - 2022 Enhancement of anti-tumor response by augmentation by cytokine signaling.
  • 2017 - 2022 Immune systems involved in the resolution of inflammation and tissue repair
  • 2020 - 2021 Development of T cell reprogramming method by metabolic and epigenomic modification
  • 2016 - 2019 Generation and Application of Stem Cell Memory T Cells
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Papers (514):
  • Tanakorn Srirat, Taeko Hayakawa, Setsuko Mise-Omata, Kensuke Nakagawara, Makoto Ando, Shigeyuki Shichino, Minako Ito, Akihiko Yoshimura. NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment. Cell reports. 2024. 43. 3. 113898-113898
  • Mayo Ikeuchi, Masanori Inoue, Hiroaki Miyahara, Wulan Apridita Sebastian, Shuya Miyazaki, Takashi Takeno, Kyoko Kiyota, Shinji Yano, Hiroshi Shiraishi, Nobuyuki Shimizu, et al. A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish. Biochemical and biophysical research communications. 2024. 699. 149551-149551
  • By Yukiko Tokifuji, Hodaka Hayabuchi, Takashi Sasaki, Mariko Hara-Chikuma, Keiji Hirota, Hayato Takahashi, Masayuki Amagai, Akihiko Yoshimura, Shunsuke Chikuma. Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition. iScience. 2024. 27. 1. 108646-108646
  • Kentaro Miyamoto, Tomohisa Sujino, Yosuke Harada, Hiroshi Ashida, Yusuke Yoshimatsu, Yuki Yonemoto, Yasuhiro Nemoto, Michio Tomura, Hassan Melhem, Jan Hendrik Niess, et al. The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis. Cell reports. 2023. 42. 8. 113005-113005
  • Setsuko Mise-Omata, Makoto Ando, Tanakorn Srirat, Kensuke Nakagawara, Taeko Hayakawa, Mana Iizuka-Koga, Hiroshi Nishimasu, Osamu Nureki, Minako Ito, Akihiko Yoshimura. SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine. Cell Reports. 2023. 42. 8. 112940-112940
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MISC (127):
  • Makoto Ando, Minako Ito, Tanakorn Srirat, Taisuke Kondo, Akihiko Yoshimura. Memory T cell, exhaustion, and tumor immunity. Immunological Medicine. 2020. 43. 1. 1-9
  • Ryota Sakai, Kyoko Komai, Mana Iizuka-Koga, Akihiko Yoshimura, Minako Ito. Regulatory T cells: Pathophysiological roles and clinical applications. Keio Journal of Medicine. 2020. 69. 1. 1-15
  • Masaki Kobayashi, Kenjiro Sawada, Mayuko Miyamoto, Akihiko Yoshimura, Erika Nakatsuka, Koji Nakamura, Seiji Mabuchi, Tadashi Kimura. Serum miR-1290 is correlated with high grade serous epithelial ovarian cancer and can be a new potential biomarker. CANCER SCIENCE. 2018. 109. 392-392
  • Kenjiro Sawada, Masaki Kobayashi, Koji Nakamura, Akihiko Yoshimura, Tadashi Kimura. Ovarian cancer exosome promotes cancer invasion by affecting peritoneal mesothelial cells and can work as a biomarker. CANCER SCIENCE. 2018. 109. 621-621
  • Masaki Kobayashi, Sawada Kenjiro, Yoshimura Akihiko, Miyamoto Mayuko, Nakatsuka Erika, Kodama Michiko, Hashimoto Kae, Mabuchi Seiji, Kimura Tadashi. Elevated level of serum miR-1290 is correlated with high-grade serous ovarian epithelial ovarian cancer and might be a potential biomarker. CANCER RESEARCH. 2018. 78. 13
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Education (2):
  • - 1985 Kyoto University
  • - 1985 Kyoto University Graduate School, Division of Natural Science
Professional career (1):
  • (BLANK) (Kyoto University)
Work history (9):
  • 2008/04 - 現在 Keio University School of Medicine professor
  • 2001 - - 九州大学 教授
  • 2001 - - professor, Kyushu University
  • 1995 - 2000 久留米 教授
  • 1995 - 2000 professor, Kurume University
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Awards (4):
  • 2022/09 - 2022 ICIS-Pfizer Award for Excellence in Cytokine & Interferon Research Discovery of Negative Regulators of Cytokine Signaling and Transcription in Immune Tolerance“
  • 2021/11 - 日本国政府 紫綬褒章
  • 2021/03 - 上原記念生命科学振興財団 上原賞
  • 1997 - 日本生化学奨励賞
Association Membership(s) (5):
THE JAPANESE CANCER ASSOCIATION ,  日本炎症再生学会 ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  日本生化学会
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