Rchr
J-GLOBAL ID:200901042882965697   Update date: Feb. 01, 2024

Nakajima Masahiro

Nakajima Masahiro
Research field  (1): Genetics
Research theme for competitive and other funds  (2):
  • 2020 - 2023 脊椎後縦靭帯骨化症の疾患感受性遺伝子の同定
  • 2000 - 2002 The changes of bone metabolism induced by quasi-microgravity and its recovery by the bone-metabolizing agents.
Papers (58):
  • Masahiro Nakajima, Masaru Koido, Long Guo, Chikashi Terao, Shiro Ikegawa. A novel CCDC91 isoform associated with ossification of the posterior longitudinal ligament of the spine works as a non-coding RNA to regulate osteogenic genes. The American Journal of Human Genetics. 2023
  • Yoshiro Yonezawa, Long Guo, Hisaya Kakinuma, Nao Otomo, Soichiro Yoshino, Kazuki Takeda, Masahiro Nakajima, Toshiyuki Shiraki, Yoji Ogura, Yohei Takahashi, et al. Identification of a functional susceptibility variant for adolescent idiopathic scoliosis that upregulates EGR1-mediated UNCX expression. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2022
  • Yoshinao Koike, Masahiko Takahata, Masahiro Nakajima, Nao Otomo, Hiroyuki Suetsugu, Xiaoxi Liu, Tsutomu Endo, Shiro Imagama, Kazuyoshi Kobayashi, Takashi Kaito, et al. Genetic insights into ossification of the posterior longitudinal ligament of the spine. 2022
  • Nao Otomo, Hsing-Fang Lu, Masaru Koido, Ikuyo Kou, Kazuki Takeda, Yukihide Momozawa, Michiaki Kubo, Yoichiro Kamatani, Yoji Ogura, Yohei Takahashi, et al. Polygenic Risk Score of Adolescent Idiopathic Scoliosis for Potential Clinical Use. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021. 36. 8. 1481-1491
  • Go Jokoji, Shingo Maeda, Kazuki Oishi, Toshiro Ijuin, Masahiro Nakajima, Hiroki Tawaratsumida, Ichiro Kawamura, Hiroyuki Tominaga, Eiji Taketomi, Shiro Ikegawa, et al. CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1. The Journal of biological chemistry. 2021. 100994-100994
more...
MISC (29):
  • 城光寺豪, 城光寺豪, 前田真吾, 中島正宏, 河村一郎, 八尋雄平, 八尋雄平, 冨永博之, 武冨榮二, 池川志郎, et al. 脊柱後縦靱帯骨化症(OPLL)組織にはosteochondral bipotentialな細胞が存在し,GWASによる原因候補遺伝子を発現する. 日本整形外科学会雑誌. 2020. 94. 3
  • 城光寺豪, 城光寺豪, 前田真吾, 中島正宏, 河村一郎, 八尋雄平, 八尋雄平, 冨永博之, 武冨榮二, 池川志郎, et al. 脊椎後縦靭帯骨化症原因候補遺伝子CDC5Lは骨芽細胞分化を抑制し,初期軟骨細胞分化を促進する. 日本整形外科学会雑誌. 2020. 94. 3
  • 城光寺豪, 城光寺豪, 前田真吾, 中島正宏, 河村一郎, 八尋雄平, 八尋雄平, 冨永博之, 武冨榮二, 池川志郎, et al. 脊椎後縦靭帯骨化症原因候補遺伝子CDC5Lは骨芽細胞分化を抑制し,初期軟骨細胞分化を促進する. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2020. 38th
  • 城光寺豪, 城光寺豪, 前田真吾, 中島正宏, 河村一郎, 八尋雄平, 八尋雄平, 冨永博之, 武冨榮二, 池川志郎, et al. 脊椎後縦靱帯骨化症原因候補遺伝子CDC5Lは初期軟骨細胞分化を促進する. 日本整形外科学会雑誌. 2020. 94. 8
  • 城光寺豪, 城光寺豪, 前田真吾, 中島正宏, 河村一郎, 八尋雄平, 冨永博之, 武冨榮二, 池川志郎, 谷口昇, et al. CDC5L, a genetically associated gene of OPLL, inhibits osteogenesis and promotes early chondrogenesis. 日本軟骨代謝学会プログラム・抄録集. 2020. 33rd
more...
Patents (2):
Lectures and oral presentations  (3):
  • 骨・関節疾患の感受性遺伝子の研究
    (日本人類遺伝学会第62回大会 2017)
  • 脊椎後縦靭帯骨化症の疾患感受性遺伝子の同定
    (第34回日本骨代謝学会学術集会 2016)
  • OPLLのゲノム研究
    (第30回日本整形外科学会基礎学術集会 2015)
Education (2):
  • 1999 - 2001 東北大学大学院 薬学研究科
  • 1995 - 1999 Tohoku University Faculty of Pharmaceutical Sciences
Work history (2):
  • 2004/04 - 現在 RIKEN
  • 2001/04 - 2004/03 Teikyo University Faculty of Pharma-Science
Awards (1):
  • 2016/06 - 日本人類遺伝学会 奨励賞
Association Membership(s) (1):
THE JAPAN SOCIETY OF HUMAN GENETICS
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