Rchr
J-GLOBAL ID:200901043100856807   Update date: Apr. 04, 2024

SEKINE Yuichi

セキネ ユウイチ | SEKINE Yuichi
Affiliation and department:
Job title: 講師
Homepage URL  (1): https://www.ncbi.nlm.nih.gov/myncbi/1NmjLj1-lM1A5/bibliography/public/
Research field  (3): Nervous system function ,  Cell biology ,  Immunology
Research keywords  (4): Axon Regeneration ,  Signal Transduction ,  Neuroscience ,  免疫学
Research theme for competitive and other funds  (9):
  • 2022 - 2025 機能性食品成分による中枢神経再生調節についての研究
  • 2019 - 2021 Establishment and analysis of a mouse model of maternal neglect based on the dysfunction of synaptic adhesion molecule
  • 2011 - 2014 癌・免疫疾患発症とシグナル異常:STAT3とNFーκBを中心として
  • 2011 - 2011 アダプター分子STAP-2によるT細胞活性制御機構の解明
  • 2009 - 2010 疾患関連シグナルにおける低分子量二重特異性ホスファターゼの機能解析
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Papers (88):
  • Yuichi Sekine, Kazuna Kikkawa, Sachie Honda, Yuto Sasaki, Shoya Kawahara, Akihiro Mizushima, Sumihito Togi, Masahiro Fujimuro, Kenji Oritani, Tadashi Matsuda. STAP-2 facilitates insulin signaling through binding to CAP/c-Cbl and regulates adipocyte differentiation. Scientific Reports. 2024. 14. 1
  • Sachie Honda, Tadashi Matsuda, Masahiro Fujimuro, Yuichi Sekine. Tyrosinase regulates the motility of human melanoma cell line A375 through its hydroxylase enzymatic activity. Biochemical and Biophysical Research Communications. 2024. 149785-149785
  • Tomu Oonishi, Kaneyasu Nishimura, Kazuyuki Takata, Masahiro Fujimuro, Yuichi Sekine. Scraping Assay as a Novel Strategy to Evaluate Axonal Regeneration Using Human-Induced Pluripotent Stem Cell-Derived Neurons. Biological and Pharmaceutical Bulletin. 2024
  • Yuto Sasaki, Shoya Kawahara, Yuichi Sekine, Jun-Ichi Kashiwakura, Kenji Oritani, Tadashi Matsuda. Potential therapeutic applications of targeting signal-transducing adaptor protein-2 in autoimmune diseases. Exploration of Immunology. 2023. 3. 6. 604-612
  • Yuichi Sekine, Xingxing Wang, Kazuna Kikkawa, Sachie Honda, Stephen M Strittmatter. Amino-terminal proteolytic fragment of the axon growth inhibitor Nogo-A (Rtn4A) is upregulated by injury and promotes axon regeneration. The Journal of biological chemistry. 2023. 105232-105232
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MISC (34):
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Works (2):
  • STAP-2による活性化T細胞排除機構の解明
    2008 - 2009
  • 自然免疫と獲得免疫をリンクする新規アダプター分子STAP-2の機能解析
    2006 - 2007
Professional career (1):
  • 博士(薬学) (北海道大学)
Work history (5):
  • 2014/07 - 2019/03 Yale University School of Medicine Associate Research Scientist
  • 2013/07 - 2014/06 Yale University School of Medicine Postdoctoral Associate
  • 2011/07 - 2013/06 Yale University School of Medicine 日本学術振興会 海外特別研究員
  • 2008 - - 北海道大学大学院 薬学研究院 衛生化学研究室 助教
  • 2004 - - 北海道大学大学院薬学研究科・衛生化学分野・助手 助手
Awards (2):
  • 2013/03 - 日本薬学会奨励賞
  • 2010 - 日本薬学会 北海道支部奨励賞
Association Membership(s) (3):
日本神経科学学会 ,  日本薬学会 ,  日本免疫学会
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