Yokoyama Toshifumi

ヨコヤマトシフミ | Yokoyama Toshifumi

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： http://www.ans.kobe-u.ac.jp/kenkyuuka/sigen/bunsi.html

Research field (1)： Zoological sciences

Research keywords (8)：組織学 , マウス , セルトリ細胞 , 遺伝学 , 性分化疾患 , 性分化 , Histology , 組織細胞生物学

Research theme for competitive and other funds (16)：

2022 - 2026 妊娠母体炎症が惹起する児の脳-身体の双方向性制御機能の破綻
2022 - 2025 Elucidation of mechanisms of generational toxicology of developmental neurotoxicity - Developmental program and epigenomic toxicity of pesticides
2021 - 2024 Developmental neurotoxicity of pesticides based on the transgenerational inheritance and localized neural progenitor and glial cells activity
2019 - 2022 殺虫剤の「生物学的モニタリングに基づく適応的リスク評価法」の開発と実践
2018 - 2022 腸内細菌叢と脳との双方向情報伝達機構の解明-ストレスによる肥満易発症の分子基盤

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Papers (125)：

Shota Murase, Youhei Mantani, Nobuhiko Ohno, Asaka Shimada, Satoki Nakanishi, Rinako Morishita, Toshifumi Yokoyama, Nobuhiko Hoshi. Regional differences in the ultrastructure of mucosal macrophages in the rat large intestine. Cell and tissue research. 2024
Shiori Kato, Toshifumi Yokoyama, Taisei Fujikawa, Yusuke Kirizuki, Youhei Mantani, Takanori Miki, Nobuhiko Hoshi. Establishment of an organ culture system to maintain the structure of mouse Müllerian ducts during development. The Journal of veterinary medical science. 2024. 86. 3
Tetsushi Hirano, Shuji Ohno, Yoshinori Ikenaka, Kanoko Onaru, Shizuka Kubo, Yuka Miyata, Mizuki Maeda, Youhei Mantani, Toshifumi Yokoyama, Collins Nimako, et al. Quantification of the tissue distribution and accumulation of the neonicotinoid pesticide clothianidin and its metabolites in maternal and fetal mice. Toxicology and applied pharmacology. 2024. 116847-116847
Yukako Hara, Asuka Shoda, Sakura Yonoichi, Yuya Ishida, Midori Murata, Mako Kimura, Makiko Ito, Sarika Nunobiki, Ayano Yoshimoto, Youhei Mantani, et al. No-observed-adverse-effect-level (NOAEL) clothianidin, a neonicotinoid pesticide, impairs hippocampal memory and motor learning associated with alteration of gene expression in cerebellum. The Journal of veterinary medical science. 2024
Yuya Ishida, Sakura Yonoichi, Yukako Hara, Asuka Shoda, Mako Kimura, Midori Murata, Makiko Ito, Sarika Nunobiki, Ayano Yoshimoto, Youhei Mantani, et al. Effect of clothianidin exposure at the no-observed-adverse-effect level (NOAEL) in a mouse model of atopic dermatitis. The Journal of veterinary medical science. 2024

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Books (6)：

獣医組織学改訂第9版-第4章血液及び骨髄(骨髄)
学窓社 2023
獣医組織学改訂第9版-第19章家禽の組織学(1.血液,2.骨髄)
学窓社 2023
獣医組織学改訂第8版-第19章家禽の組織学(1.血液,2.骨髄)
学窓社 2020
獣医組織学改訂第8版-第4章血液及び骨髄(骨髄)
学窓社 2020
獣医組織学改訂第7版-第4章血液及び骨髄(骨髄)
学窓社 2017

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Lectures and oral presentations (289)：

発生中のマウスミュラー管の構造を維持する器官培養法の検討
(2023)
精巣化が脆弱なB6Js-XYPOSマウス性腺におけるSox9発現の消退
(2023)
クロチアニジンがアトピー性皮膚炎症状に及ぼす影響について
(2023)
ネオニコチノイド系農薬曝露による腸内細菌叢変動メカニズムに関する研究
(2023)
マウス未分化性腺の精巣化へのビタミンD受容体(Vdr)の関与
(2023)

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Education (1)：

- 2003 Kobe University Graduate School of Science and Technology

Professional career (2)：

修士(農学) (神戸大学)
博士(農学) (神戸大学)

Work history (1)：

Former Institution /Organization Kagawa University Faculty of Medicine School of Medicine Research Associate

Awards (1)：

2010/07 - 日本先天異常学会第50回日本先天異常学会学術集会優秀ポスター賞 Sry 導入XXマウスにおける雄性生殖腺の形態学的解析

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