Rchr
J-GLOBAL ID：200901043534017722   Update date: Mar. 31, 2024

NAKAGAWA Hidehiko

ナカガワ ヒデヒコ | NAKAGAWA Hidehiko
Affiliation and department：
Nagoya City University

About Nagoya City University


Job title： Professor
Homepage URL  (1)： http://www.phar.nagoya-cu.ac.jp/hp/ykg/Yakka/index.html
Research field  (2)： Chemical biology ,  Pharmaceuticals - chemistry and drug development
Research keywords  (6)： medicinal chemistry ,  chemical probe ,  caged compunds ,  reactive oxygen species ,  nitric oxide ,  包括脳ネットワーク
Research theme for competitive and other funds  (27)：
  • 2023 - 2026 Development of near-infrared light-responsive flexible nitric oxide-emitting nanomaterials.
  • 2021 - 2026 In-cell chemistry of supersulfur species in biology
  • 2021 - 2026 Management of international relation and facility for promotion of research on sulfur biology
  • 2021 - 2024 Application of light-controllable nitric oxide donor for lower urinary tract symptom
  • 2020 - 2023 光制御可能なNOドナー「NORD-1」の難治性EDへの応用
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Papers (147)：
  • Naoya Ieda, Akira Nakamura, Natsumi Tomita, Kei Ohkubo, Ryo Izumi, Yuji Hotta, Mitsuyasu Kawaguchi, Kazunori Kimura, Hidehiko Nakagawa. A BODIPY-picolinium-cation conjugate as a blue-light-responsive caged group. RSC Advances. 2023. 13. 26375-26379
  • Naoya Ieda, Mitsuyasu Kawaguchi, Hidehiko Nakagawa. Substituent Effects at the <i>N</i>-Nitrosoaminophenol Moiety of a Photoinduced-Electron-Transfer-Driven Nitric Oxide Releaser. Chemical and Pharmaceutical Bulletin. 2023. 71. 6. 447-450
  • Naoya Ieda, Masato Sawada, Runa Oguchi, Masato Itoh, Seina Hirakata, Daisuke Saitoh, Akito Nakao, Mitsuyasu Kawaguchi, Kazunobu Sawamoto, Toshitada Yoshihara, et al. An Optochemical Oxygen Scavenger Enabling Spatiotemporal Control of Hypoxia. Angewandte Chemie International Edition. 2023. 62. 20
  • Zuoyue Liu, Yuta Okada, Yuma Ichinose, Daisuke Saitoh, Naoya Ieda, Seiji Yamasaki, Kunihiko Nishino, Hidehiko Nakagawa, Mamoru Fujitsuka, Yasuko Osakada. Vanadyl Naphthalocyanine-Doped Polymer Dots for Near-Infrared Light-Induced Nitric Oxide Release and Bactericidal Effects. ACS Applied Nano Materials. 2023. 6. 2. 1487-1495
  • Daisuke Saitoh, Ayumi Suzuki, Naoya Ieda, Zuoyue Liu, Yasuko Osakada, Mamoru Fujitsuka, Mitsuyasu Kawaguchi, Hidehiko Nakagawa. Photoinduced NO-Release from Polymer Dots Doped with an Ir(III) Complex and N-Methyl-N-nitroso-4-aminophenol. Organic & Biomolecular Chemistry. 2023
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MISC (59)：
  • 坂本 眞伍, 小松 徹, 渡邉 力也, 張 翼, 井上 大輝, 川口 充康, 中川 秀彦, 植野 高章, 奥坂 拓志, 本田 一文, et al. 1分子酵素活性プロファイリング技術のリキッドバイオプシーへの応用. JSMI Report. 2021. 14. 2. 135-135
  • 坂本 眞伍, 小松 徹, 渡邉 力也, 張 翼, 井上 大輝, 川口 充康, 中川 秀彦, 植野 高章, 奥坂 拓志, 本田 一文, et al. 1分子酵素活性プロファイリング技術のリキッドバイオプシーへの応用. JSMI Report. 2021. 14. 2. 135-135
  • 山口遥己, 川口充康, 井田智章, 松永哲郎, 家田直弥, 赤池孝章, 中川秀彦. S-sulfhydryl化タンパク質解析を志向したhydropersulfideラベル化蛍光プローブの開発. 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会講演要旨集. 2021. 2021
  • Naoya Ieda, Hidehiko Nakagawa. Development of Photoredox-reaction-driven NO-releasing Reagents and Application for Photomanipulation of Vasodilation. Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 2020. 78. 11. 1048-1057
  • 坂本眞伍, 小松徹, 渡邉力也, 張翼, 井上大輝, 川口充康, 中川秀彦, 植野高章, 奥坂拓志, 本田一文, et al. 1分子酵素活性プロファイリングによる疾患関連酵素の超高感度検出. 日本生化学会大会(Web). 2020. 93rd. 1. 39-42
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Lectures and oral presentations  (21)：
  • ENPP1活性検出蛍光プローブの開発とケミカルスクリーニング
    (メディシナルケミストリーシンポジウム講演要旨集 2017)
  • Inhibition of Amyloid-beta Fibril Formation and Its Cytotoxicity by Antioxidant-Conjugated Amyloid-beta C-Terminal Peptides
    (FREE RADICAL BIOLOGY AND MEDICINE 2016)
  • Chamical Biology for Pharmaceutical Sciences-Novel Approaches for Exploring Cellular Functions with Non-drug Chemicals Foreword
    (YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 2016)
  • Photo-manipulation of vasodilation with a novel photo-controllable nitric oxide releaser based on N-nitrosoaminophenol
    (NITRIC OXIDE-BIOLOGY AND CHEMISTRY 2014)
  • Hydrogen sulfide releaser with xanthone-type photocages
    (NITRIC OXIDE-BIOLOGY AND CHEMISTRY 2014)
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Education (2)：
  • 1990 - 1995 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • 1986 - 1990 The University of Tokyo Faculty of Pharmaceutical Sciences
Professional career (1)：
  • Ph.D.
Work history (10)：
  • 2013/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2010/10 - 2014/03 科学技術振興機構 兼任研究員(さきがけ)
  • 2007/04 - 2013/03 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2004/05 - 2007/03 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2000/04 - 2004/04 放射線医学総合研究所 主任研究員
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Committee career (1)：
  • 2017/10 - 現在 World Health Organization International Non-proprietary Names (INN) Expart
Awards (2)：
  • 2016/03 - Pharmaceutical Society of Japan Award for Divisional Scientific Promotion
  • 2014 - Society for Free Radical Research Japan Award for Scientific Promotion
Association Membership(s) (5)：
THE JAPANESE PHOTOCEHMISTRY ASSOCIATION ,  THE SOCIETY OF ELECTRON SPIN SCIENCE AND TECHNOLOGY ,  SOCIETY FOR FREE RADICAL RESEARCH JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  The Chemical Society of Japan
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