Rchr
J-GLOBAL ID:200901043945356552   Update date: Feb. 01, 2024

Kozaki Ken'ichi

コザキ ケンイチ | Kozaki Ken'ichi
Affiliation and department:
Job title: Professor
Research field  (7): Pathobiochemistry ,  Oral medicine ,  Oral medicine (pathology) ,  Tumor diagnostics and therapeutics ,  Experimental pathology ,  Obstetrics and gynecology ,  Fetal medicine/Pediatrics
Research keywords  (37): がん抑制遺伝子 ,  癌浸潤・転移 ,  がん遺伝子 ,  癌抑制遺伝子 ,  マウス皮下移植自然転移モデル ,  術後再発 ,  EPC-1 ,  血管新生 ,  cyclooxygenase2 ,  エピゲノム異常 ,  網羅的発現解析 ,  リンパ行性転移 ,  コラーゲン ,  capsin ,  COX-2選択的阻害剤 ,  DNA過剰メチル化 ,  エナメル上皮腫 ,  REDF ,  治療ゲノム学 ,  マウス皮下移植モデル ,  リンパ節転移 ,  扁平上皮 ,  miR-137 ,  miR-193a ,  DNAメチル化異常 ,  artificial tongue ,  Palatal Augmentation Prosthesis ,  squamous cell carcinoma ,  oral cancer ,  extracellular matrix ,  molecular target ,  microRNA ,  metastasis ,  epigenome ,  genome ,  分子腫瘍学 ,  molecular oncology
Research theme for competitive and other funds  (17):
  • 2014 - 2017 Integrative screening of cancer-associated microRNAs for medical application to RNA-based therapeutics
  • 2014 - 2016 Establishment of gene promoter activity detection system for separation of viable and nonviable cells
  • 2011 - 2014 Integrative screening of tumor-suppressive microRNAs for medical application to RNA-based therapeutics
  • 2010 - 2013 Development of diagnostic tools for personalized cancer medicine by genomic and epigenomic analyses
  • 2008 - 2011 Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
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Papers (63):
MISC (10):
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Patents (5):
Books (2):
  • 肝細胞癌の早期診断 : 画像と分子マーカー : 厚生労働科学研究費補助金(肝炎等克服緊急対策研究事業)/ 有井滋樹, 松井修代表研究者監・編集
    アークメディア 2012 ISBN:9784875831570
  • Transplants and implants in otology II
    Kugler Publications 1992 ISBN:9062990843
Lectures and oral presentations  (10):
  • Function-based screening of EMT-suppressive microRNA by CDH1/E-cadherin-promoter activity
    (Symposia “MicroRNA for cancer therapy and diagnosis”, 72st Annual Meeting of Japanese Cancer Association 2013)
  • Function-based screening of EMT-suppressive microRNA in cancer cells.
    (2013 SNUCRI & SNUCH Cancer Symposium 2013)
  • Methylation-based screening of tumor-suppressive microRNAs in cancer cells
    (Symposia “Recent progress of non-coding RNA and cancer”, 71st Annual Meeting of Japanese Cancer Association 2012)
  • Function-based screening of tumor-suppressive microRNAs silenced by DNA hypermethylation in cancer cells
    (Symposia “Cancer epigenetics: Breakthroughs in basic research and clinical applications”, 70th Annual Meeting of Japanese Cancer Association 2011)
  • Function-based screening of tumor-suppressive microRNAs silenced by DNA hypermethylation in cancer cells
    (2011)
more...
Works (2):
  • がん細胞の病態特異的DNAメチル化異常による悪性形質獲得機構の解明
    小崎 健一
  • 癌抑制遺伝子型microRNAの統合的スクリーニングと核酸医薬への応用
    小崎 健一
Education (4):
  • 1990 - 1994 Nagoya University Graduate School of Medicine Department of Oral Surgery
  • - 1994 Nagoya University School of Medicine / Graduate of Medicine Doctoral Course at the Graduate School of Medicine, Nagoya Univercity Oral and Maxillofacial Surgery
  • 1983 - 1989 Hiroshima University Faculty of Dentistry
  • - 1989 Hiroshima University Scool of Dentistry
Professional career (1):
  • Doctor of Medical Science (Nagoya University School of Medicine/Graduate School of Medicine)
Work history (8):
  • 2014/04 - 現在 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Dental Pharmacology Professor
  • 2010/06 - 2014/03 Department of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University Associate Professor
  • 2005/05 - 2010/05 Department of Genome Medicine, Hard Tissue Genome Research Center, Tokyo Medical and Dental University Associate Professor
  • 2004/04 - 2005/04 Department of Pharmacology, Osaka Dental University Associate Professor
  • 2001/01 - 2004/03 Department of Pathology, Aichi Medical University School of Medicine Assistant Professor
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Committee career (4):
  • 2014/06 - 現在 Japanese Association for Oral Biology Councilor member
  • 2014/06 - 現在 歯科基礎医学会 評議員
  • 2011/01 - 現在 日本癌学会 評議員
  • 2011/01 - 現在 Japanese Cancer Association Councilor member
Awards (2):
  • 2012/11 - Osaka Cancer Research Foundation basic and clinical cancer research projects
  • 2001/11 - Kowa Life Science Foundation Kowa Life Science Foundation Molecular mechanism and suppression of tumor growth via apoptosis induced specifically to in endothelial cells by anti-angiogenic factor caspin/PEDF/EPC-1
Association Membership(s) (4):
JAPANESE ASSOCIATION FOR ORAL BIOLOGY ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPANESE CANCER ASSOCIATION
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