Rchr
J-GLOBAL ID:200901045612362078   Update date: Mar. 19, 2024

MURAKAMI Takashi

ムラカミ タカシ | MURAKAMI Takashi
Affiliation and department:
Job title: Professor
Research field  (1): Tumor diagnostics and therapeutics
Research theme for competitive and other funds  (21):
  • 2022 - 進行性メラノーマの腫瘍免疫原性再プログラム化とその分子標的研究
  • 2021 - 細菌の嫌気部位集積性を利用した悪性黒色腫に対する新規免疫誘導方法の開発
  • 2017 - 2020 新規免疫チェックポイント分子DC-HILを標的としたがん治療の研究
  • 2016 - 2020 ヒトへの外挿性を向上させた培養細胞資源開発と供給体制整備 (AMED)
  • 2018 - 悪性黒色腫における免疫編集の役割とその治療標的化の研究
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Papers (198):
  • Ichikawa T, Suekane A, Nakahata S, Iha H, Shimoda, K, Murakami T, Morishita K. Inhibition of PRMT5/MEP50 arginine methyltransferase activity causes cancer vulnerability in NDRG2low Adult T-cell leukemia/lymphoma. Int J Mol Sci. 2024. 25. 2. 2842
  • Horiuchi Y, Nakamura A, Imai T, Murakami T. Infection of tumor cells with Salmonella typhimurium mimics immunogenic cell death and elicits tumor-specific immune responses. PNAS Nexus. 2024. 3. 1. pgad484
  • Cox KE, Turner MA, Amirfakhri S, Lwin TM, Hosseini M, Ghosh P, Obonyo M, Murakami T, Hoffman RM, Yazaki PJ, et al. Humanized anti-CEA Antibodies Brightly Target and Label Gastric Cancer in Orthotopic Mouse Models. J Surg Res. 2024. 293. 701-708
  • Chinsuwan T, Hirabayashi K, Mishima S, Hasegawa A, Tanaka M, Mochizuki H, Shimoi A, Murakami T, Yagyu S, Shimizu K, et al. Ligand-based, piggyBac-engineered CAR-T cells targeting EGFR are safe and effective against non-small cell lung cancers. Mol Ther Oncolytics. 2023. 31
  • Inoue S, Takeuchi Y, Horiuchi Y, Murakami T, Odaka A. CD69 on tumor-infiltrating cells correlates with neuroblastoma suppression by PD-1/PD-L1 blockade. J Surg Res. 2023. 289. 190-201
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MISC (63):
  • Aya Matsui, Takashi Murakami, Taichi Ezaki. Expression of CXCL17 in tumors promotes their progression by inducing CXCL17-responding CD11b(+) Gr-1(high) cells. ANGIOGENESIS. 2014. 17. 3. 745-745
  • 小俣 大樹, 根岸 洋一, 村上 孝, 野水 基義, 新槙 幸彦. ラミニン由来AG73ペプチド修飾リポソームによるsiRNA導入効率の評価. 日本薬学会年会要旨集. 2010. 130年会. 4. 271-271
  • 井上 泰一, 村上 孝, 遠藤 照顕, 小林 英司, 星野 雄一. 糖尿病ラットに対する人工真皮のscaffoldとしての有用性. 日本整形外科学会雑誌. 2009. 83. 8. S1058-S1058
  • Profile of GFP-transgenic Jinhua Pigs (1) Growth and reproductive performance, and GFP expression in tissues. Bulletin of Shizuoka Prefectural Research Institute of Animal Industry, Swine & Poultry Research Center. 2009. 2. 1-7
  • 井上 泰一, 村上 孝, 安食 孝士, 遠藤 照顕, 小林 英司, 星野 雄一. 糖尿病ラットにおける骨髄由来細胞付加人工真皮の創傷治癒メカニズム. 日本整形外科学会雑誌. 2008. 82. 8. S1183-S1183
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Books (13):
  • 「免疫力が高まる27の生活習慣」
    (株)法研 2020
  • 生物発光モデル動物作製によるがん生物学研究(27章)「がんの分子イメージング」
    化学同人 2015
  • CXCL17 (chemokine (C-X-C motif) ligand 17),Atlas Genet Cytogenet Oncol Haematol
    Institute for Scientific and Technical Information of the French National Center for Scientific Research (INIST-CNRS) 2015
  • Immunomodulation Therapy by the Control of Immune Cell Trafficking (Chapter 10).,Current Immunosuppressive Therapy in Organ Transplantation
    Nova Science Publishers, Inc 2015
  • Immunomodulation Therapy by the Control of Immune Cell Trafficking (Chapter 10). Current Immunosuppressive Therapy in Organ Transplantation
    Nova Science Publishers, Inc 2015
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Lectures and oral presentations  (6):
  • Salmonella infected-melanoma cells elicit anti-melanoma T-cell responses.
    (第50回日本免疫学会学術集会 2021)
  • Activation of antigen-presenting cells by stress-induced senescence-like tumor cells.
    (第50回日本免疫学会学術集会 2021)
  • Intra-cellular infection of tumor with Salmonella typhimurium primes tumor-antigen specific T-cell responses.
    (第80回日本癌学会学術総会 2021)
  • Potential role of senescent-tumor cells toward anti-tumor immunity.
    (第80回日本癌学会学術総会 2021)
  • ポータブルシーケンサーFlongleを用いた呼吸器ウイルス感染症の診断法についての検討.
    (第95回日本感染症学会総会・学術講演会 2021)
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Education (2):
  • 1993 - 1997 The University of Tokyo Graduate School, Division of Medical Sciences
  • 1986 - 1992 Gunma University Faculty of Medicine
Professional career (1):
  • 博士(医学) (東京大学大学院)
Work history (8):
  • 2016/04 - 現在 Gunma University Faculty of Medicine
  • 2011/04 - 2016/08 Professor
  • 2007/04 - 2011/03 Associate Professor
  • 2003/09 - 2007/03 Lecturer
  • 2001/12 - 2003/08 米国 National Cancer Institute (National Institute of Health) Visiting Fellow
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