Komaki Motohiro

Affiliation and department：
Job title： professor

Research field (1)： Conservative dentistry and endodontics

Research keywords (5)：再生医療 , セメント質 , 細胞転写技術 , 骨細胞生物学 , 血管生物学

Research theme for competitive and other funds (15)：

2019 - 2023 歯周炎発症カニクイザルを用いた病原細菌の特定と細菌伝播経路の解明
2018 - 2022 Exploration of periodontitis-related molecules by using spontaneous periodontitis monkey
2015 - 2019 Effects of stem cell-derived exosomes on periodontal regeneration
2015 - 2018 Novel periodontal regeneration using secreted factors from mesenchymal stem cells and clarification of its regenerative mechanisms.
2013 - 2017 Development of phototherapy using lasers and LEDs for the treatment and prevention of periodontitis and peri-implantitis

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Papers (20)：

Kengo Iwasaki, Keiko Akazawa, Mizuki Nagata, Motohiro Komaki, Yihao Peng, Makoto Umeda, Tetsuro Watabe, Ikuo Morita. Angiogenic Effects of Secreted Factors from Periodontal Ligament Stem Cells. Dentistry Journal. 2021. 9. 1. 9-9
Kengo Iwasaki, Motohiro Komaki, Keiko Akazawa, Mizuki Nagata, Naoki Yokoyama, Tetsuro Watabe, Ikuo Morita. Spontaneous differentiation of periodontal ligament stem cells into myofibroblast during ex vivo expansion. JOURNAL OF CELLULAR PHYSIOLOGY. 2019. 234. 11. 20377-20391
Kengo Iwasaki, Keiko Akazawa, Mizuki Nagata, Motohiro Komaki, Izumi Honda, Chikako Morioka, Naoki Yokoyama, Hirohito Ayame, Kazumasa Yamaki, Yuichi Tanaka, et al. The Fate of Transplanted Periodontal Ligament Stem Cells in Surgically Created Periodontal Defects in Rats. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019. 20. 1
Motohiro Komaki, Yuri Numata, Chikako Morioka, Izumi Honda, Masayuki Tooi, Naoki Yokoyama, Hirohito Ayame, Kengo Iwasaki, Atsuko Taki, Noriko Oshima, et al. Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis. STEM CELL RESEARCH & THERAPY. 2017. 8
Mizuki Nagata, Kengo Iwasaki, Keiko Akazawa, Motohiro Komaki, Naoki Yokoyama, Yuichi Izumi, Ikuo Morita. Conditioned Medium from Periodontal Ligament Stem Cells Enhances Periodontal Regeneration. TISSUE ENGINEERING PART A. 2017. 23. 9-10. 367-377

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MISC (10)：

青木章, 水谷幸嗣, 谷口陽一, 小牧基浩, 岩田隆紀, 和泉雄一. 歯周治療におけるEr:YAGレーザーを用いた新しいアプローチ-Er-LCPT & Er-LBRTの理論と実践 Er-LCPT法の術式の実際重度歯周ポケットとインプラント周囲炎への応用. 日本歯科評論. 2019. 79. 4. 117-130
Aoki A, Mizutani K, Taniguchi Y, KOmaki M, Ejiri K, Mikami M, Izumi Y. Periodontal pocket therapy using Er:YAG laser: systematic review of literature and introduction of a new treatment procedure. The Journal of Japan Society for Laser Surgery and Medicine. 2017. 38. 2. 167-178
Keiko Tanaka, Kengo Iwasaki, Karine el Feghali, Motohiro Komaki, Isao Ishikawa, Yuichi Izumi. Comparison of characteristics of periodontal ligament cells obtained from outgrowth and enzyme-digested culture methods. ARCHIVES OF ORAL BIOLOGY. 2011. 56. 4. 380-388
K. Iwasaki, M. Komaki, K. Mimori, E. Leon, Y. Izumi, I. Ishikawa. IL-6 induces osteoblastic differentiation of periodontal ligament cells. JOURNAL OF DENTAL RESEARCH. 2008. 87. 10. 937-942
E. R. Leon, K. Iwasaki, M. Komaki, T. Kojima, I. Ishikawa. Osteogenic effect of interleukin-11 and synergism with ascorbic acid in human periodontal ligament cells. JOURNAL OF PERIODONTAL RESEARCH. 2007. 42. 6. 527-535

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