2019 - 2022 Research for kidney repair mechanisms in acute kidney injury using disease specific iPS cells
2019 - 2022 腎疾患におけるアミノ酸キラリティを標的とした分子病態の解明研究
2017 - 2022 進行性腎障害における慢性炎症の意義とそれに立脚した分子予防学の構築
2018 - 2021 指定難病の普及・啓発に向けた統合研究
2016 - 2019 International comparison of clinicopathological features in Japanese patients with diabetic nephropathy and nephrosclerosis with those in Asian countries
2016 - 2018 Pathophysiology of kidney diseases based on amino acids and related biomarker development
2015 - 2018 Progressive kidney disease and inflammation
2015 - 2017 Identification of new myeloid-derived fibrosis-inducing cells accounting for cardiorenal connection in diabetic nephropathy
2015 - 2017 Pathophysiological analysis using iPS cells from patient with Renal Coloboma syndrome
2014 - 2017 Longitudinal study of progression and improvement factors of chronic kidney disease using health checkup cohort
2014 - 2017 Involvement of LPA1-MRTF-SRF in renal fibrosis
2014 - 2017 Clinical significance of serum autotaxin (ATX) and phosphatidylserine-specific phospholipase A1 (PS-PLA1) levels in human kidney disease
2014 - 2017 Association of anti-erythropoietin receptor antibodies with organ involvement of diabetic complications
2014 - 2017 Gene analysis of renal coloboma syndrome and biomarker development of acute kidney injury
2013 - 2016 Research of biomarkers that predict relapse of rapidly progressive glomerulonephritis and reflect long-term prognosis.
2013 - 2015 Possible circulating permeability factors related to proteinuria in nephrotic syndrome
2012 - 2015 Pathogenesis of immune cells in progressive kidney disease
2012 - 2015 Comparison of outcomes and their related risk factors observed in Asian patients with those in Japanese diabetic nephropathy patients
2012 - 2015 糖尿病性腎症ならびに腎硬化症の診療水準向上と重症化防止にむけた調査・研究
2011 - 2013 The pharmacokinetic study on enhanced vancomycin renal clearance in patients with malignancies.
2009 - 2012 糖尿病性腎症の病態解明と新規治療法確立のための評価法の開発
2010 - 2012 Therapeutic approaches of AKI by adipose-derived mesenchymal cells, and urinary biomarker search in AKI
2008 - 2010 Possible involvement of CD45^+/collagen I^+ dual positive cells in renal fibrosis and cardiorenal syndrome.
2006 - 2007 Role of fibrocytes, a newly identified tone marrow-derived cells, in the pathogenesis of renal fibrosis
2004 - 2005 Role of IP-10 and its receptor CXCR3 in development and progress fibrosis in kidney
2002 - 2003 Role of MCP-1/CCR2 in renal fibrosis
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Papers (583):
Miho Shimizu, Kengo Furuichi, Tadashi Toyama, Masayuki Yamanouchi, Junichi Hoshino, Shinji Kitajima, Akinori Hara, Yasunori Iwata, Norihiko Sakai, Yukio Yuzawa, et al. Polar vasculosis is associated with better kidney outcome in type 2 diabetes with biopsy-proven diabetic kidney disease: A multicenter cohort study. Journal of diabetes investigation. 2023. 14. 11. 1268-1278
Megumi Oshima, Tadashi Toyama, Yusuke Nakade, Daichi Yomogida, Takahiro Yuasa, Keisuke Horikoshi, Taichirou Minami, Hisayuki Ogura, Shiori Nakagawa, Taro Miyagawa, et al. Association Between Risperidone Use and Kidney Function Decline in Patients with Schizophrenia: A Retrospective Cohort Study. Clinical therapeutics. 2023
Tadashi Toyama, Miho Shimizu, Taihei Yamaguchi, Hidekazu Kurita, Tetsurou Morita, Megumi Oshima, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Atsushi Hashiba, et al. A comprehensive risk factor analysis using association rules in people with diabetic kidney disease. Scientific reports. 2023. 13. 1. 11690-11690
Yuta Yamamura, Norihiko Sakai, Yasunori Iwata, David Lagares, Akinori Hara, Shinji Kitajima, Tadashi Toyama, Taro Miyagawa, Hisayuki Ogura, Koichi Sato, et al. Myocardin-related transcription factor contributes to renal fibrosis through the regulation of extracellular microenvironment surrounding fibroblasts. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 7. e23005
Goro Sakurai, Tadashi Toyama, Toshiaki Tokumaru, Akinori Hara, Yuta Yamamura, Shiori Nakagawa, Megumi Oshima, Taro Miyagawa, Hisayuki Ogura, Shinji Kitajima, et al. Association between Light-Intensity and Moderate-to-Vigorous-Intensity Physical Activity Habits and Kidney Dysfunction: A General Population Cohort Study. Health & Social Care in the Community. 2023
- 1992 Kanazawa University Graduate School, Division of Medicine
- 1988 Kanazawa University
Professional career (1):
医学博士
Work history (2):
2007/09 - 金沢大学大学院 教授
1995 - 1997 米国ハーバード大学Brigham and Women病院腎臓部門研究員
Committee career (7):
2016/06 - 現在 Japanese Society of Nephrology Board Members
2015 - 現在 Board Members
2013 - 現在 Board Members
2013 - 現在 Japanese Society of Internal Medicine Board Members
2012 - 現在 Board Members
2008 - 現在 The Japanese Society of Dialysis Therapy Board Members
2012/01 - 2014/12 日本臨床検査医学会 支部理事
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Awards (6):
2020/02 - 日本腎臓財団学術賞
2006 - Takeda Science Foundation
2001 - 日本リウマチ学会優秀賞
2000 - 日本腎臓学会褒賞学会賞(大島賞)
1996 - 日本炎症学会奨励賞
1995 - Japan Society for the Promotion of Science
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Association Membership(s) (6):
Japan College of Rheumatology
, 日本透析医学会
, Japanese Society of Laboratory Medicine
, 米国腎臓学会
, Japanese Society of Nephrology
, Japanese Society of Internal Medicine