Tsuda Yuko

ツダユウコ | Tsuda Yuko

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (7)： molecular recognition , structure-activity relationship , peptide , 医薬品化学 , Molecular Pharmacology , Biopharmacology , Chemical Pharmacology

Research theme for competitive and other funds (8)：

1999 - ペプチド性鎮痛薬の開発
1999 - Development of Peptidic Analgesics
1998 - 抗腫瘍活性物質の探索
1998 - Research of substance with anti-tumour activity
1994 - 凝固線溶系酵素に対する多機能性阻害剤のデザイン

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MISC (44)：

A Miyazaki, T Yokoi, Y Tachibana, R Enomoto, E Lee, G Bokonyi, G Keri, Y Tsuda, Y Okada. Design and synthesis of novel type somatostatin analogs with antiproliferative activities on A431 tumor cells. TETRAHEDRON LETTERS. 2004. 45. 33. 6323-6327
Y Fujita, Y Tsuda, TY Li, T Motoyama, M Takahashi, Y Shimizu, T Yokoi, Y Sasaki, A Ambo, A Kita, et al. Development of potent bifunctional endomorphin-2 analogues with mixed mu-/delta-opioid agonist and delta-opioid antagonist properties. JOURNAL OF MEDICINAL CHEMISTRY. 2004. 47. 14. 3591-3599
Y Jinsmaa, A Miyazaki, Y Fujita, TY Li, Y Fujisawa, K Shiotani, Y Tsuda, T Yokoi, A Ambo, Y Sasaki, et al. Oral bioavailability of a new class of mu-opioid receptor agonists containing 3,6-bis[Dmt-NH(CH2)(n)]2(1H)-pyrazinone with central-mediated analgesia. JOURNAL OF MEDICINAL CHEMISTRY. 2004. 47. 10. 2599-2610
A431腫瘍細胞において生抑制活性を示す新規ソムトスタチン類似体のデザインと合成. テトロヘドロン・レター. 2004. 45, 6323
μ-lδ- オピオイド・アゴニストおよび δ-オピオイド・アンタゴニストの性質をあわせもった強力な二機能性エンドモルフィン2類似体の開発. メディシナル・ケミストリー. 2004. 47. 14. 3591

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Patents (2)：

二機能性トロンビン阻害剤
Bivalent thrombin inhibitors

Books (2)：

エンドモルフィンと関連オピオイドペプチド
ヴィタミンとホルモン 2002
Endomorphins and related opioid peptides
Vitamines and Hormones 2002

Education (2)：

- 1975 University of Toyama Faculty of Pharmacy and Pharmaceutical Sciences
- 1975 University of Toyama Faculty of Pharmaceutical Science

Professional career (1)：

Ph.D. (Kyoto University)

Work history (9)：

1995 - 2002 Kobe Gakuin University
1995 - 2002 lecturer, Kobe Gakuin University
2002 - - 神戸学院大学助教授
2002 - - Research Associate, Kobe Gakuin University
1975 - 1995 Kobe Gakuin University

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Association Membership(s) (4)：

JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , Japan Society for Proteases in Pathophysiology , 日本ペプチド学会 , 日本薬学会

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