Rchr
J-GLOBAL ID：200901047267595393
Update date: Jan. 30, 2024
Park Sam-Yong
パク サンヨン | Park Sam-Yong
Affiliation and department：
Job title：
Professor
Other affiliations (1)：
Homepage URL (1)：
http://www.tsurumi.yokohama-cu.ac.jp/pdl/index.html
Research field (3)：
Biophysics
, Structural biochemistry
, Biodiversity and systematics
Research keywords (5)：
構造創薬化学
, 構造生物学
, Biology
, Structural Biology
, Biophysical
Research theme for competitive and other funds (29)：
- 2021 - 2024 Structure and functional analysis of the SARS-CoV-2 Nucleocapsid Protein
- 2019 - 2024 Structural analysis of various light-driven reaction mechanisms of light-sensitive proteins.
- 2018 - 2021 Molecular mechanism of photoactivation of a light-regulated adenylate cyclase
- 2015 - 2018 Structural Study on Mental Disease Gene Product Protein
- 2012 - 2017 Host cell competnecy for negative-stranded RNA viruses
- 2012 - 2017 Molecular basis of host cell competency in virus infection
- 2013 - 2016 The mechanism analysis of influenza RNA polymerase
- 2011 - 2013 Elucidation of the true picture of the hemoglobin allosteric equilibrium
- 2011 - 2013 Structural Study on neuron protein complex essential for memory and learning
- 2011 - 2012 Analyses of centromeric chromatin structure
- 2010 - 2012 Analysis of the outer membrane BAM complex
- 2009 - 2011 Structural basis for an essential subunit interaction in influenza virus RNA polymerase PB1-PB2
- 2009 - 2010 The structural analysis of centromere specific nucleosome
- 2008 - 2009 タイマータンパク質EA4の計時機構解明を目指した研究
- 2007 - 2009 Signal discrimination analyses based on the domain structure of soluble guanylate cyclase
- 2007 - 2008 Crystal structures of penicillin binding proteins from Haemophilus influenzae
- 2007 - 2008 Structure and function of autotransporter proteins from pathogenic bacteria
- 2003 - 2008 膜結合型AAA-ATPase p47/p97複合体による細胞膜認識とその制御
- 2001 - 2002 NO標的酵素(可溶性グアニル酸シクラーゼー)のX線結晶構造解析
- 2000 - 2002 Structural Analysis of Ethylene (Plant Hormone) Sensor Protein
- 1999 - 2000 一酸化窒素(NO)還元機構解明
- 病気関連のタンパク質のX線結晶構造解析
- EYAタンパク質のX線結晶構造解析
- 時間を認識するタンパク質のX線結晶構造解析
- 魚ヘモグロビンのX線結晶構造解析
- Crystal Structure about of Disease Protein
- Crystal Structure of EYA protein
- Crystal Structure of TIME protein
- Crystal Structure of Fish Hemoglobins
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Papers (123)：
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Naito Ishimoto, Jae-Hyun Park, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R H Tame, Asuka Inoue, Sam-Yong Park. Structural basis of CXC chemokine receptor 1 ligand binding and activation. Nature communications. 2023. 14. 1. 4107-4107
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Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, et al. Structural insights into the HBV receptor and bile acid transporter NTCP. Nature. 2022. 606. 7916. 1027-1031
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深野 顕人, 大嶋 美月, 九十田 千子, 相崎 英樹, 大木 規央, 朴 三用, 脇田 隆字, 若江 亨祥, 渡士 幸一, 村松 正道. 感染受容体NTCPの多量体化が導くB型肝炎ウイルス細胞内侵入機構の解明. 日本薬学会年会要旨集. 2022. 142年会. 26M-pm15
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深野 顕人, 大嶋 美月, 九十田 千子, 相崎 英樹, 大木 規央, 朴 三用, 脇田 隆字, 若江 亨祥, 渡士 幸一, 村松 正道. SLC10A1/NTCP多量体形成が制御するB型肝炎ウイルス細胞内侵入機構の解析. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-382]
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Kento Fukano, Mizuki Oshima, Senko Tsukuda, Hideki Aizaki, Mio Ohki, Sam-Yong Park, Takaji Wakita, Kousho Wakae, Koichi Watashi, Masamichi Muramatsu. NTCP oligomerization occurs downstream of the NTCP-EGFR interaction during hepatitis B virus internalization. Journal of Virology. 2021
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MISC (54)：
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Structural and Functional Insights into a Photoactivated Adenylyl Cyclase. 2017. 59. 2. 102-107
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Sam-Yong Park, Jeremy R. H. Tame. Seeing the light with BLUF proteins. Biophysical Reviews. 2017. 9. 2. 169-176
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Ayana Sato-Tomita, Naohisa Happo, Sam-Yong Park, Koichi Hayashi, Yuji C. Sasaki, Naoya Shibayama. X-Ray Fluorescence Holography for Proteins: Application to Hemoglobin and Myoglobin. BIOPHYSICAL JOURNAL. 2017. 112. 3. 579A-579A
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Ayana Sato-Tomita, Shin-ichi Adachi, Sam-Yong Park, Yuji C. Sasaki, Koichi Hayashi, Naoya Shibayama. New Structural Analysis Methods for Hemoglobin Crystals. Time-Resolved Cryogenic X-Ray Crystallography with Extended Pulsed-Laser Pumping and 3D Imaging by X-Ray Fluorescence Holography. BIOPHYSICAL JOURNAL. 2016. 110. 3. 160A-160A
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Hirano Takako, Sugiyama Kanako, Sakaki Yuta, Uehara Rie, Shiraishi Haruka, Hakamata Wataru, Park Sam-Yong, Nishio Toshiyuki. Chitin Oligosaccharide Deacetylase from Marine Bacteria : Enzymological Characters, Three-dimensional Structure, and the Roles of Its Product. Bulletin of applied glycoscience. 2015. 5. 2. 113-119
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Works (6)：
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高熱菌チトクロムCYP119のX線結晶構造解析
1999 - 2001
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High Resolution Structural Origin of Thermostability
1999 - 2001
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Mg(II)-Fe(II)混成ヘモグロビンのX線結晶構造解析
1996 - 2001
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Crystal Structure of Mg(I)-Fe(II)Hydrid Hemoglobin
1996 - 2001
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一酸化窒素還元酵素P450norのX線結晶構造解析
1996 - 2000
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Professional career (1)：
- (BLANK) (Osaka University)
Work history (2)：
- 2010 - 現在 Yokohama City University
- Yokohama City University International College of Arts and Sciences Medical Life Science Graduate School of Medical Life Science Department of Medical Life Science
Committee career (1)：
Awards (1)：
Association Membership(s) (3)：
THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN
, PROTEIN SCIENCE SOCIETY OF JAPAN
, 日本生物物理学会
