Rchr
J-GLOBAL ID:200901048160638568   Update date: Jan. 30, 2024

Michigami Toshimi

ミチガミ トシミ | Michigami Toshimi
Affiliation and department:
Job title: 部長
Research field  (3): Metabolism and endocrinology ,  Nephrology ,  Physiology
Research keywords  (5): リン代謝 ,  カルシウム ,  骨代謝 ,  Calcium/Phosphate Metabolism ,  Bone Metabolism
Research theme for competitive and other funds  (23):
  • 2021 - 2024 Novel Molecular Mechanism for Hereditary Hypophosphatemia
  • 2021 - 2024 骨細胞機能障害の解析と治療ターゲットの探索ー遺伝性骨疾患を対象としてー
  • 2018 - 2021 Role of Osteocytes in Phosphate Sensing and Its Relation to Skeletal Maturation
  • 2018 - 2021 Analysis of mechanism of bone fragility and effects of drugs in osteogenesis imperfecta using a graft model for enchondral bone formation
  • 2017 - 2020 Local phosphorus production system in bone mineralization: role of alkaline phosphatase
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Papers (112):
  • Natsumi Yamamura-Miyazaki, Toshimi Michigami, Keiichi Ozono, Katsusuke Yamamoto, Yukiko Hasuike. Factors associated with 1-year changes in serum fibroblast growth factor 23 levels in pediatric patients with chronic kidney disease. Clinical and experimental nephrology. 2022. 26. 10. 1014-1021
  • Shinsuke Onuma, Saori Kinoshita, Shigeki Shimba, Keiichi Ozono, Toshimi Michigami, Masanobu Kawai. The Lack of Bmal1, a Core Clock Gene, in the Intestine Decreases Glucose Absorption in Mice. Endocrinology. 2022. 163. 9
  • Toshimi Michigami, Kanako Tachikawa, Miwa Yamazaki, Tatsuro Nakanishi, Masanobu Kawai, Keiichi Ozono. Growth-related skeletal changes and alterations in phosphate metabolism. Bone. 2022. 161. 116430-116430
  • Miwa Yamazaki, Masanobu Kawai, Saori Kinoshita, Kanako Tachikawa, Tatsuro Nakanishi, Keiichi Ozono, Toshimi Michigami. Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression. Bone. 2021. 151. 116036-116036
  • Masaru Kato, Toshimi Michigami, Kanako Tachikawa, Momoko Kato, Ichiro Yabe, Tomohiro Shimizu, Takuya Asaka, Yoshimasa Kitagawa, Tatsuya Atsumi. Novel mutation in the ALPL gene with a dominant negative effect in a Japanese family. JOURNAL OF BONE AND MINERAL METABOLISM. 2021
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MISC (35):
  • Yasuhisa Ohata, Takuo Kubota, Shinji Takeyari, Taichi Kitaoka, Yukako Nakano, Kei Miyata, Chieko Yamada, Keiichi Ozono, Yasuki Ishihara, Hirofumi Nakayama, et al. Mutational analysis of the PHEX gene and genotype-phenotype correlation in 37 Japanese patients with X-linked hypophosphatemic rickets. JOURNAL OF BONE AND MINERAL RESEARCH. 2019. 34. 272-272
  • 向井 昌史, 山本 威久, 武鑓 真司, 大幡 泰久, 長谷川 泰浩, 北岡 太一, 窪田 拓生, 山本 勝輔, 溝口 好美, 道上 敏美, et al. ビタミンD欠乏性くる病による内反膝(O脚)の程度と関連する因子の検討. 日本内分泌学会雑誌. 2019. 95. 1. 467-467
  • Yasuhisa Ohata, Shinji Takeyari, Taichi Kitaoka, Hirofumi Nakayama, Varoona Bizaoui, Yukako Nakano, Kenichi Yamamoto, Kei Miyata, Keiko Yamamoto, Takuo Kubota, et al. Comprehensive Genetic Analysis by Targeted Next Generation Sequencing and Genotype-phenotype Correlation of 47 Japanese Patients with Osteogenesis Imperfecta. JOURNAL OF BONE AND MINERAL RESEARCH. 2018. 33. 301-301
  • Ryuichi Watanabe, Takeshi Miyamoto, Toshimi Michigami, Seiji Fukumoto, Masaya Nakamura, Morio Matsumoto. Enpp1 regulates Klotho expression under phosphate overload conditions. JOURNAL OF BONE AND MINERAL RESEARCH. 2017. 32. S325-S325
  • 窪田 拓生, 中山 尋文, 北中 幸子, 道上 敏美, 藤原 幾磨, 福本 誠二, 長谷川 高誠, 坂本 優子, 大薗 恵一. 本邦における小児ビタミンD欠乏症の発症率. 日本骨代謝学会学術集会プログラム抄録集. 2017. 35回. 165-165
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Education (2):
  • - 1988 Osaka University Faculty of Medicine Medical School
  • - 1988 Osaka University School of Medicine School of Medicine
Professional career (1):
  • Doctor(Medical Science) (Osaka University)
Work history (16):
  • 2003 - 現在 同上 部長
  • 2003 - 現在 Chief, Department of Bone and Mineral Research
  • 2002 - 現在 Osaka University Graduate School of Dentistry
  • 1997 - 2003 Osaka Women's and Children's Hospital Research Institute
  • 1997 - 2003 Senior Researcher, Department of
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Committee career (5):
  • - 現在 日本ステロイドホルモン学会 評議員
  • - 現在 日本小児内分泌学会 評議員
  • - 現在 日本内分泌学会 評議員
  • - 現在 日本骨代謝学会 評議員
  • 2002 - The Japanese Society for Bone and Mineral Metabolism Councilor
Awards (2):
  • 2013 - 日本骨代謝学会 学術賞
  • 2012 - 日本小児内分泌学会 学術賞
Association Membership(s) (6):
アメリカ骨代謝学会 ,  日本内分泌学会 ,  日本骨代謝学会 ,  American Society for Bone and Mineral Research ,  The Japan Endocrine Society ,  The Japanese Society for Bone and Mineral Metabolism
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