Kanemaki Masato

カネマキマサト | Kanemaki Masato

Affiliation and department：
Other affiliations (2)：

SOKENDAI School of Life Science Department of Genetics Professor
The University of Tokyo Graduate School of Science, Department of Biological Sciences Professor

Homepage URL (2)： http://kanemaki-lab.sakura.ne.jp/jpn/ , https://www.nig.ac.jp/labs/MolFunc/Eng/

Research field (3)： Applied molecular and cellular biology , Genetics , Molecular biology

Research keywords (10)： Auxin-inducible degron , Genomic instability , Chromosome , Genomics , Genome editing , Protein degradation , DNA replication , DNA repair , Homologous recombination , Cell engineering

Research theme for competitive and other funds (13)：

2023 - 2028 オーキシンデグロン法によるタンパク質寿命操作
2021 - 2025 細胞及び動物個体で迅速タンパク質分解を可能にするAID2法の発展的基盤技術の開発
2022 - 2024 非ゲノム情報による複製開始領域と複製タイミング制御メカニズムの解明
2020 - 2022 非ゲノム情報による複製開始点制御の解明
2018 - 2021 Improvement of the AID technology through chemical biology approaches

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Papers (88)：

Kosuke Yamaguchi, Xiaoying Chen, Brianna Rodgers, Fumihito Miura, Pavel Bashtrykov, Frédéric Bonhomme, Catalina Salinas-Luypaert, Deis Haxholli, Nicole Gutekunst, Bihter Özdemir Aygenli, et al. Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells. Nature Communications. 2024. 15. 1
Emily M Pujadas Liwag, Xiaolong Wei, Nicolas Acosta, Lucas M Carter, Jiekun Yang, Luay M Almassalha, Surbhi Jain, Ali Daneshkhah, Suhas S P Rao, Fidan Seker-Polat, et al. Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism. Genome Biology. 2024. 25. 1. 77-77
Ai Kiyomitsu, Toshiya Nishimura, Shiang Jyi Hwang, Satoshi Ansai, Masato T Kanemaki, Minoru Tanaka, Tomomi Kiyomitsu. Ran-GTP assembles a specialized spindle structure for accurate chromosome segregation in medaka early embryos. Nature Communications. 2024. 15. 1. 981-981
Ryusuke Suzuki, Masato T Kanemaki, Takeshi Suzuki, Katsuji Yoshioka. Overexpression of JNK-associated leucine zipper protein induces chromosomal instability through interaction with dynein light intermediate chain 1. Genes to Cells. 2023
Shaun Scaramuzza, Rebecca M Jones, Martina Muste Sadurni, Alicja Reynolds-Winczura, Divyasree Poovathumkadavil, Abigail Farrell, Toyoaki Natsume, Patricia Rojas, Cyntia Fernandez Cuesta, Masato T Kanemaki, et al. TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells. Nature Communications. 2023. 14. 1. 5071-5071

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Patents (10)：

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Books (14)：

ヒトの減数分裂期相同組換えにおいて環状DNAが生じる!?(実験医学 News & Hot Paper Digest)
羊土社 2022 ISBN:9784758125567
High-efficient protein knockdown by a new generation of the auxin-inducible degron technology, AID2
2021
Targeted protein degradation by use of a degron technology
2021
ゲノム編集技術を応用した製品開発とその実用化
技術情報協会 2021
Protein knockdown by the use of the auxin-inducible degron technology
2020 ISBN:9784758125352

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Lectures and oral presentations (62)：

Targeted protein degradation with the power of plant
(MBSJ2023 Symposium (Synthetic biotechnology and beyond) 2023)
Replication initiation in human cells
(2023)
改良オーキシンデグロン AID2 を利用して、ヒト細胞の DNA 複製機構を理解する
(RNA Frontier meeting 2023 2023)
The mechanism defining replication initiation zones in human cells
(Cold Spring Harbor Meeting on Eukaryotic DNA Replication and Genome Maintenance 2023)
A targeted protein knockdown with the power of plants
(2nd TPD Conference in Japan 2023)

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Education (3)：

1998 - 2001 Chiba University Graduate School of Science and Technology PhD program
1996 - 1998 Chiba University Graduate School of Science and Technology Master program
1992 - 1996 Chiba University School of Science Department of Biology

Professional career (1)：

PhD (Chiba University)

Work history (8)：

2022/04 - 現在 Department of Biological Sciences, Graduate School of Science, The University of Tokyo Interlocking faculty Professor (Interlocking faculty member)
2016/04 - 現在 National Institute of Genetics Department of Chromosome Science Professor
2013/10 - 2017/03 JST PRESTO fellow
2010/10 - 2016/03 National Institute of Genetics Center for Frontier Research Associate Professor
2006/07 - 2010/09 Osaka University School of Science, Department of Biological Sciences Assistant Professor

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Committee career (5)：

2023/01 - 現在 The Molecular Biology Society of Japan Trustee
2021/01 - 現在 The Molecular Biology Society of Japan Career path committee
2020 - 現在 The Journal of Biochemistry Associate Editor
2018 - 現在 The Japanese Society of Genome Editing Future plan committee
2018 - 現在 Cell Structure and Function Associate Editor

Awards (1)：

2024/02 - Foundation for Promotion of Material Science and Technology of Japan Yamzaki Teiichi Prize

Association Membership(s) (5)：

The Japanese Society for Genome Editing , JAPAN SOCIETY FOR CELL BIOLOGY , THE JAPANESE CANCER ASSOCIATION , THE GENETICS SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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