2017 - 2020 Retinoic acid-deficient renal mesangial cells are responsible for the development of diabetic nephropathy
2011 - 2013 Nuclear receptors as molecular regulator and chemopreventive targets of colon cancer stem cells.
2008 - 2010 Retinoic acid metabolizing enzyme CYP26A1 is a candidate oncogene, and a possible therapeutic target for cancers.
2005 - 2007 Biological barrier and human diseases
2005 - 2006 Regulation of bile canalicular barrier by a novel tight junction protein claudin-2 during cholestasis
ビタミンA誘導体を用いた全く新しいがん治療法の開発は可能か?
細胞間接着構造であるタイト結合の機能調節による上皮バリアの制御は可能か?
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Papers (88):
Daisuke Kyuno, Masatoshi Tateno, Yusuke Ono, Kazufumi Magara, Kumi Takasawa, Akira Takasawa, Makoto Osanai. Common pathological findings in the heart in COVID-19-related sudden death cases: An autopsy case series. Heliyon. 2023. 9. 10. e20564
及能 大輔, 廣橋 良彦, 和田 朝香, 島 宏彰, 九冨 五郎, 真柄 和史, 高澤 久美, 高澤 啓, 竹政 伊知朗, 小山内 誠. 癌幹細胞マーカーに対する自己抗体を利用した乳癌患者の予後予測(Prediction of Prognosis in Breast Cancer Patients Using Autoantibodies to Cancer Stem Cell Markers). 日本癌学会総会記事. 2023. 82回. 2116-2116
及能 大輔, 高澤 啓, 高澤 久美, 真柄 和史, 小山内 誠. 膵癌患者の予後と癌進展におけるJAM-Aの役割(Junctional Adhesion Molecule-A may play a role in the progression of pancreatic cancer). 日本癌学会総会記事. 2022. 81回. J-2053
真柄 和史, 高澤 啓, 高澤 久美, 及能 大輔, 小山内 誠. タイト結合分子JAM-Aの異常高発現が乳がんの悪性化に関与する(Elevated expression of JAM-A contributes malignant progression of breast cancer). 日本癌学会総会記事. 2022. 81回. P-3247
The tight junction, intercellular seal as a cell-signaling player; Protocols for examination for its status.
Elsevier 2010
Tight junctions and cancer development, Encyclopedia of Cancer. M. Schwab Osanai M
Springer 2008
Expression of carbohydrate antigens in pancreatic cancer: Handbook of immunohistochemistry and in situ hybridization of human carcinomas. MA. Hayat. Osanai M
Elsevier 2006
Education (3):
- 1997 Asahikawa Medical University
- 1997 Asahikawa Medical College
- 1993 Asahikawa Medical University School of Medicine Medical Course
Professional career (1):
MD, PhD
Association Membership(s) (4):
日本病理学会
, 日本癌学会
, Japanese Cancer Association
, Japanese Society of Pathology