Kamaike Kazuo

カマイケカズオ | Kamaike Kazuo

Affiliation and department：
Job title： Associate Professor

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (2)：薬化学 , Pharmaceutical Chemistry

Research theme for competitive and other funds (9)：

2001 - 遺伝子に作用する医薬品の開発
2001 - Development of new therapeutic agents against disease-related genes
1997 - ホスホロチオアートおよびホスホロジチオアート型オリゴヌクレオチドの合成
1997 - Synthesis of phosphorothioate and phosphorodithioate-linked oligonucleotides
1996 - 緩和な塩基性条件下除去できる5′-位水酸基の保護基を用いるオリゴヌクレオチドの合成

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MISC (46)：

KAWASHIMA Etsuko, KAMAIKE Kazuo. Design, Synthesis and Evaluation of Pyrrole polyamide-nucleoside Hybrids and Oligonucleotides Conjugated Hybrid as a Novel Gene Expression Control Compound-. YAKUGAKU ZASSHI. 2010. 130. 3. 355-375
Efficient synthesis of [2-¹⁵N]guanosine and 2'-deoxy[2-¹⁵N]guanosine derivatives using N-(tert-butyldimethylsilyl)[¹⁵N]phthalimide as a ¹⁵N-labeling reagent. Nucleosides, Nucleotide, and Nucleic Acids. 2006. 25, 29-35
Design, synthesis and evaluation of oligomer conjugated MGBpolyamide-nucleoside hybrid as a novel gene expression control compound. Nucleic Acids Symp. Ser. 2005. 49, 327-328
K Kamaike, K Hirose, Y Kayama, E Kawashima. Synthesis of oligonucleoside phosphorodithioates by the H-phosphonothioate method. TETRAHEDRON LETTERS. 2004. 45. 30. 5803-5806
Design, synthesis and analysis of a pyrrolepolyamide-nucleoside hybrid. Nucleic Acids Symp. Ser. 2004. No. 48, 55-56

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Patents (6)：

ヌクレオシドのスクシニル化法
2-{2- (モノメトキシトリチルオキシ ) エチルチオ } エチル基及び該基の使用法
複素環化合物へのイミド基の導入法(特許出願)
新規修飾ヌクレオシドおよびその製造法さらにはそれを用いたオリゴヌクレオチド類の製造法
高分子保護基として多糖類誘導体を用いる均一系オリゴヌクレオチドの合成法(国内および国外特許)

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Works (9)：

遺伝情報制御分子としてのMGBポリアミド-ヌクレオシド及び-オリゴヌクレオチドハイブリッド化合物の創製と評価
2004 -
Desin, synthesis and evaluation of MGBpolyamide-nucleoside and -oligonucleotide hybrides as a novel gene expression control compound
2004 -
オリゴヌクレオチド類の合成研究
1997 -
Study on Synthesis of Oligonucleotides
1997 -
安定同位体標識オリゴヌクレオチドの合成
1995 -

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Education (6)：

- 1987 Tokyo Institute of Technology Science of Engineering
- 1987 Tokyo Institute of Technology Graduate School, Division of Science and Engineering
- 1982 Chiba Institute of Technology
- 1982 Chiba Institute of Technology Graduate School, Division of Engineering
- 1980 Chiba Institute of Technology Faculty of Engineering

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Professional career (2)：

Doctor of Science (Tokyo Institute of Technology)
Master of Engineering (Chiba Institute of Technology)

Work history (10)：

2019 - 現在 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
1997 - 現在 Assistant Professor (Lecturer),
1997 - 2018 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
1989 - 1996 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
1989 - 1996 Reserch Assosiate, School of Pharmacy, Tokyo University

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Awards (1)：

1988 - 財団法人手島工業教育資金団研究奨励賞

Association Membership(s) (11)：

International Society of Heterocyclic Chemistry (ヘテロ環化学国際学会) , 日本糖質学会 , International Society of Nucleic Acids Chemistry(国際核酸化学会) , 有機合成化学協会 , 日本化学会 , 日本薬学会 , International Society of Heterocyclic Chemistry , International Society of Nucleic Acids Chemistry , The Society of Synthetic Organic Chemistry, Japan , The Chemical Society of Japan , The Pharmaceutical Society of Japan

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