Rchr
J-GLOBAL ID:200901049946216680
Update date: Apr. 06, 2024
Murayama Kazutaka
ムラヤマ カズタカ | Murayama Kazutaka
Affiliation and department:
Job title:
Associate Professor
Homepage URL (2):
http://db.tohoku.ac.jp/whois/detail/3322e369ace9c5c513f6ed491e5b6b80.html
,
http://db.tohoku.ac.jp/whois/e_detail/3322e369ace9c5c513f6ed491e5b6b80.html
Research field (1):
Structural biochemistry
Research keywords (3):
生物物理化学
, 生体高分子
, 構造解析
Research theme for competitive and other funds (9):
- 2021 - 2024 The role of post-proteolytic aminopeptidases in skeletal muscle homeostasis
- 2018 - 2022 Development of a basis for establishing the ultimate transplantation medicine that does not require the administration of immunosuppressive drugs
- 2018 - 2021 Contribution of protein recycling system for the maintenance of skeletal muscle mass
- 2015 - 2019 Establishment of next-generation diabetes treatment by construction of tailor-made cell isolation system
- 2015 - 2018 Elucidation of regulatory mechanism of RhoGEF by multidomains cooperation
- 2015 - 2018 Elucidation of substrate recognition of choline lysoplasmalogen-specific phospholipase D
- 2012 - 2015 Regulation of Bach2 intrinsically disordered region by ligand
- 2012 - 2014 Biomedical engineering approach to establish a new evaluation system for osteoconductivity by focusing on the protein adsorption properties to biomaterials
- 2009 - 2011 Regulation of immune cell responses by heme
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Papers (139):
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Kazushige Hirata, Aoi Takahara, Satoshi Suzuki, Shumei Murakami, Kumi Kawaji, Akie Nishiyama, Mina Sasano, Mariko Shoji-Ueno, Emiko Usui, Kazutaka Murayama, et al. Helical peptides with disordered regions for measles viruses provide new generalized insights into fusion inhibitors. iScience. 2024. 27. 2. 108961-108961
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Manabu Aoki, Hiromi Aoki-Ogata, Haydar Bulut, Hironori Hayashi, Nobutoki Takamune, Naoki Kishimoto, Hiroki Tanaka, Nobuyo Higashi-Kuwata, Shin-Ichiro Hattori, Debananda Das, et al. GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants. Science advances. 2023. 9. 28. eadg2955
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Shion Osana, Yasuo Kitajima, Suzuki Naoki, Kazutaka Murayama, Hiroaki Takada, Ayaka Tabuchi, Yutaka Kano, Ryoichi Nagatomi. The aminopeptidase LAP3 suppression accelerates myogenic differentiation via the AKT-TFE3 pathway in C2C12 myoblasts. Journal of cellular physiology. 2023
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鈴木 聡志, 天野 陽斗, 薄井 友輔, 河治 久実, 笹野 美奈, 西山 瑛絵, 平松 佳樹, 橋本 浩一, 村山 和隆, 児玉 栄一, et al. タンパク質間相互作用を標的とするRSウイルスの新薬更補創出. 日本小児科学会雑誌. 2023. 127. 2. 231-231
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鈴木 聡志, 黒田 実央, 河治 久実, 村山 和隆, 林 宏典, 大石 真也, 児玉 栄一. 新型コロナウイルスへの創薬に応用できるタンパク質間相互作用. 日本小児科学会雑誌. 2023. 127. 2. 235-235
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MISC (61):
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長名 シオン, 北嶋 康雄, 鈴木 直輝, 高田 拓明, 村山 和隆, 永富 良一. アミノペプチダーゼによる筋分化制御メカニズムの解明. 日本筋学会学術集会プログラム・抄録集. 2022. 8回. 144-144
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Shion Osana, Kazutaka Murayama, Ryoichi Nagatomi. The impact of intracellular aminopeptidase on C2C12 myoblast proliferation and differentiation. Biochemical and biophysical research communications. 2020. 524. 3. 608-613
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Shion Osana, Kazutaka Murayama, Naoki Suzuki, Hiroaki Takada, Takahiro Kubota, Ryoichi Nagatomi. Inhibition of leucine aminopeptidase affects myocyte proliferation and differentiation. FASEB JOURNAL. 2020. 34
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河原光希, 小山貴之, 酒瀬川信一, 村山和隆, 杉森大助, 杉森大助. コリン型リゾプラズマローゲン特異的ホスホリパーゼDの基質認識におけるPhe211およびTyr258の役割. 日本生物工学会大会講演要旨集. 2018. 70th. 200-200
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前田浩, 村山和隆, 渡邉君子, 後藤昌史, 山形洋平. 高純度組換え体ラット膵臓カルボキシペプチダーゼ製剤の作出. 日本農芸化学会大会講演要旨集(Web). 2018. 2018
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Books (2):
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Metal Ions in Life Sciences vol.10
Springer Science 2011
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遺伝子工学集中マスター
羊土社 2006
Education (1):
- - 1998 Toyohashi University of Technology Graduate School, Division of Engineering 機能材料工学
Professional career (1):
- Engineering (Toyohashi University of Technology)
Work history (4):
- 2008/04 - Graduate School of Biomedical Engineering, Tohoku University Associate Professor
- 2005/01 - 2008/03 東北大学先進医工学研究機構
- 2001/09 - 2004/12 理化学研究所ゲノム科学総合研究センター
- 1998/04 - 2001/08 Free University of Berlin
Association Membership(s) (3):
日本生物物理学会
, 蛋白質科学会
, 日本結晶学会
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