Rchr
J-GLOBAL ID：200901050089152769
Update date: Mar. 02, 2024
Inoue Hiroko
イノウエ ヒロコ | Inoue Hiroko
Affiliation and department：
Job title：
Professor
Research field (3)：
Immunology
, Molecular biology
, Functional biochemistry
Research theme for competitive and other funds (30)：
- 2022 - 2025 COVID-19の長期後遺症に関わるEBウイルス再活性化制御因子の探索
- 2022 - 2025 エピジェネティクスを基盤としたアレルギー疾患における難治化機序の解明
- 2020 - 2023 脂肪由来幹細胞による唾液腺特異的傷害モデルマウスの組織再生と促進因子の網羅的解析
- 2020 - 2023 EBウイルス遺伝子導入マウスによるシェーグレン症候群発症機構の解明
- 2019 - 2022 Elucidation of the onset mechanism of chronic fatigue mediated by herpes virus and search for its regulator
- 2017 - 2020 Generation of salivary gland-specific injury model mouse and elucidation of repair mechanism by EGFR2 / MUC1 pathway
- 2016 - 2019 Pathogenesis and regulation of herpes virus related diseases
- 2015 - 2018 Elucidation of the salivary secretion regulation mechanism through mitochondrial function control by estrogen
- 2015 - 2018 The molecular mechanism of salivary dysfunction amelioration by calorie restriction
- 2014 - 2017 Evaluation of effectiveness of equol for salivary secretion and the elucidation of the action mechanism.
- 2013 - 2016 Pathological analysis of autoimmune sialadenitis using human dental pulp
- 2012 - 2015 Study of autoimmune reaction induced by Epstein-Brr virus (EBV)-encoded small RNA (EBER)
- 2011 - 2014 Analysis of salivary secretory function via Sirt1 activation
- 2011 - 2013 Effects of resveratrol on salivary secretion
- 2011 - 2013 Differentiation of iPS cells into salivary glands
- 2009 - 2011 Mechanism of EBV induced salivary gland disorder via TLR
- 2008 - 2010 Genetic analysis of xerostomia associated with lifestyle-related diseases.
- 2008 - 2010 Evaluation of stemness on salivary gland side population cells
- 2008 - 2010 Protective effect of SOD on reactive oxygen species-induced salivary gland dysfunction.
- 2008 - 2010 A study of clustrin for the treatment of hyposalivation
- 2007 - 2009 Molecular genetics study of gutter-shaped root (GSR) in inbred mice using RNAi analysis.
- 2007 - 2008 Pathogenesis of Epstein-Barr virus on tissue specific autoimmune disease in humanized mice
- 2006 - 2007 酸化ストレスによる外分泌腺機能障害機構の解明
- 2006 - 2007 Establishment of the standard degree of oral function classified by age.
- 2006 - 2007 Investigation into the mechanism of tumorigenesis using p53-deficient epithelial cells
- 2005 - 2006 Identification of chromosomal region(s) influencing tooth root development in mouse
- 2005 - 2006 DEVELOPMENT OF CULTURE METHODS FOR EXOCRINE GLAND STEM CELLS USING GENE-TRANSDUCED FEEDER CELLS AND THEIR APPLICATION FOR TREATMENT
- 2005 - 2006 Searching the tissue specific autoimmune disease related gene by linkage analysis and establishment of a diagnosis method
- 2004 - 2005 The mechanism of exocrine gland disorder through estrogen and/or endocrine disruptors
- 2003 - 2005 内分泌撹乱物質ならびにエストロジエンによる外分泌線障害成立機序の解明
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Papers (57)：
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Ryoko Ushikoshi-Nakayama, Tomoe Yamazaki, Daisuke Omagari, Naoyuki Matsumoto, Hiroko Inoue, Chiyoko Nukuzuma, Seiji Nishino, Ichiro Saito. Evaluation of the benefits of neutral bicarbonate ionized water baths in an open-label, randomized, crossover trial. Scientific Reports. 2024. 14. 1
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Shakya Supriya, Ryoko Ushikoshi-Nakayama, Tomoe Yamazaki, Daisuke Omagari, Keiko Aota, Hiroko Inoue, Naoyuki Matsumoto, Ichiro Saito. Effects of polyphenols in non-centrifugal cane sugar on saliva secretion: <i>in vitro</i> and <i>in vivo</i> experiments and a randomized controlled trial. Journal of Clinical Biochemistry and Nutrition. 2023. 72. 2. 171-182
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Yoko Yoshino, Takahiro Imamura, Shigeo Yamachika, Tomoko Ohshima, Ryoko Ushikoshi-Nakayama, Hiroko Inoue, Ichiro Saito, Yoichi Nakagawa. Endoplasmic reticulum stress affects mouse salivary protein secretion induced by chronic administration of an α1-adrenergic agonist. Histochemistry and cell biology. 2022
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Tomoe Yamazaki, Ryoko Ushikoshi-Nakayama, Supriya Shakya, Daisuke Omagari, Naoyuki Matsumoto, Chiyoko Nukuzuma, Tomoko Komatsu, Masaichi Chang-il Lee, Hiroko Inoue, Ichiro Saito. The effects of bathing in neutral bicarbonate ion water. Scientific Reports. 2021. 11. 1
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Naoyuki Matsumoto, Daisuke Omagari, Ryoko Ushikoshi-Nakayama, Tomoe Yamazaki, Hiroko Inoue, Ichiro Saito. Hyperglycemia Induces Generation of Reactive Oxygen Species and Accelerates Apoptotic Cell Death in Salivary Gland Cells. Pathobiology. 2021. 1-8
ｍore...
MISC (3)：
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梁 洪淵, 井上 裕子, 亀山 眞由美, 新美 愛, 高橋 綾子, 伊藤 由美, 村松 敬, 玉置 洋, 斎藤 一郎. ドライマウス(口腔乾燥症)に対するイソフラボンの唾液分泌促進効果の検討. 日本抗加齢医学会総会プログラム・抄録集. 2013. 13回. 251-251
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K Tsubota, Y Ohashi, A Higuchi, H Inoue, T Doi, C Mataki, T Kodama, Y Hayashi, Saito, I. A novel cell adhesion inhibitor, K-7174, reduces lymphocyte infiltration and increases tear production in Sjogren's syndrome model mouse. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2003. 44. U437-U437
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J Shimazaki, S Shimmura, H Inoue, K Tsubota. Anti-inflammatory effects of amniotic membrane grafting in ocular surface disorders. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2000. 41. 4. S453-S453
Books (3)：
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DNAからみた角膜疾患の診断、角膜上皮へ遺伝し導入できれば、何が可能か?
やさしい分子免疫学、診断と治療社 1998
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サイトカイン産生能・サイトカイン測定法「TFT」
リンパ球機能検索法 中外医学社 1994
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RA滑膜由来T細胞ハイブリドーマから産生されるサイトカインの検討(共著)
リウマチ’91.メディカルレビュー社 1991
Professional career (1)：
Work history (6)：
- 2017/04 - 現在 Nihon Pharmaceutical University
- 2013/04 - 2017/03 Nihon Pharmaceutical University
- 2011/06 - 2013/03 Tsurumi University School of Dental Medicine
- 2005/07 - 2011/05 Tsurumi University School of Dental Medicine
- 2003/04 - 2005/03 Tsurumi University School of Dental Medicine
- 1999 - 2003 New York University Post Doctoral Fellow, Department of Microbiology
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Association Membership(s) (5)：
日本口腔ケア学会
, 日本薬学会
, 日本抗加齢医学会
, 日本分子生物学会
, 日本免疫学会
