Rchr
J-GLOBAL ID：200901050188594820   Update date: Apr. 12, 2023

Uchino Tadashi

Uchino Tadashi
Homepage URL  (1)： https://researchmap.jp/read0003949
Research field  (1)： Pharmaceuticals - health and biochemistry
Research keywords  (11)： THP-1 cells ,  hydroperoxide ,  CVM ,  安全性 ,  酸化チタン ,  皮膚感作性評価法 ,  3次元培養ヒト皮膚モデル ,  nanotoxicology ,  TiO2 ,  Evalation method ,  3D-human skin model
Research theme for competitive and other funds  (5)：
  • 2015 - 2018 Lipid peroxidation and diseases: their prevention by food constituents
  • 2011 - 2015 Development of an Alternative Model of Animal Skin Sensitization Test
  • 2007 - 2009 ナノマテリアルの経皮毒性に関する評価手法の開発に関する研究
  • 2006 - 2008 生活関連化学物質の皮膚感作性等のインビトロ評価法に関する研究
  • 2006 - 2008 Study of in vitro evalation method of skin sensitization inducing environmental chemicals
Papers (50)：
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MISC (26)：
  • UCHINO Tadashi, TAKEZAWA Toshiaki, YAMASHITA Kunihiko, KOJIMA Hajime, SHIMIZU Kumiko, AKIYAMA Takumi, IKARASHI Yoshiaki. Vitrigel-Skin Sensitization Test method utilizing a collagen vitrigel membrane chamber using human acute monocytic leukemia cell line. Annual Meeting of the Japanese Society of Toxicology. 2013. 38. Suppl. S257-S257
  • UCHINO Tadashi, TAKEZAWA Toshiaki, YAMASHITA Kunihiko, KOJIMA Hajime, SHIMIZU Kumiko, MIYANAGA Yuko, IKARASHI Yoshiaki, NISHIMURA Tetsuji. Cytokine release activity of cells composed of skin model utilizing a vitrigel chamber for skin sensitization test. Annual Meeting of the Japanese Society of Toxicology. 2012. 37. Suppl.1. S278-S278
  • 徐 結苟, 佐川 容子, 二口 充, 深町 勝巳, 五十嵐 良明, 西村 哲治, 古川 文夫, 内野 正, 酒々井 眞澄, 森田 明理, et al. ナノ二酸化チタニウム粒子の皮膚発がん性修飾作用の欠如 ラットとマウスを用いた検討. 日本毒性病理学会講演要旨集. 2011. 27回. 141-141
  • TAKEZAWA Toshiaki, FUKUDA Maya, MCINTOSH-AMBROSE Winnette, KO Ji-Ae, ELISSEEFF Jennifer, HAGA Sanae, OZAKI Michitaka, KATO Kiyoko, WANG Pi-Chao, UCHINO Tadashi, et al. Development of Novel Cell Culture Systems Utilizing the Advantages of Collagen Vitrigel Membrane. YAKUGAKU ZASSHI. 2010. 130. 4. 565-574
  • 深町 勝巳, 徐 結苟, 二口 充, 飯郷 正明, 内野 正, 西村 哲治, 広瀬 明彦, 管野 純, 津田 洋幸. フラーレン(C60)のラット肺発がんプロモーション作用(Promotion Effects of Fullerene (C60) on Rat Lung Carcinogenesis). 日本癌学会総会記事. 2009. 68回. 38-38
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Patents (2)：
  • Evaluation of skin sensitization test method using three-dimensional skin model utilizing vitrigel chamber
  • three-dimentional human skin model consisting of dendritic cells
Lectures and oral presentations  (3)：
  • Construction of three-dimensional human skin model consisting of dendritic cells, keratinocytes and fibroblasts on collagen vitrigel membrane
    (6th World Congress on Alternatives & Animal Use in the Life Sciences 2007)
  • 樹状細胞を含む三次元ヒト皮膚モデルの構築とその皮膚感作性試験への応用
    (日本薬学会第127年会シンポジウム 2007)
  • Construction of three-dimensional human skin model consisting of dendritic cells, keratinocytes and fibroblasts on collagen vitrigel membrane
    (6th World Congress on Alternatives & Animal Use in the Life Sciences 2007)
Education (4)：
  • - 1991 Chiba University
  • - 1991 Chiba University Graduate School, Division of Pharmaceutical Sciences Pharmaceutical Sciences
  • - 1989 Chiba University Faculty of Pharmaceutical Sciences
  • - 1989 Chiba University Faculty of Pharmaceutical Science Pharmaceutical Sciences
Professional career (1)：
  • Doctor(Pharmacy) (Chiba University)
Work history (3)：
  • 2010/04 - 現在 NIHS Division of Environmental Chemistry Senior Resercher
  • 1996/04 - 2010/03 NIHS Division of Environmental Chemistry Senior Resercher
  • 1993/04 - 1996/03 NIHS Division of Organic Chemistry Resercher
Committee career (3)：
  • 2014/08 - 現在 日本過酸化脂質・抗酸化物質学会 幹事
  • 2013/01 - 現在 日本動物実験代替法学会 評議員
  • 2017/01 - 2021/12 日本動物実験代替法学会 3Rs啓発委員会委員長
Awards (1)：
  • 2012/12 - JSAAE Award for Scientific Reseach Development of an alternative test for skin sensitization
Association Membership(s) (11)：
JAPAN SOCIETY ON WATER ENVIRONMENT ,  THE JAPANESE SOCIETY OF TOXICOLOGY ,  日本動物実験代替法学会 ,  日本薬学会 ,  日本香粧品科学会 ,  日本過酸化脂質・抗酸化物質学会 ,  Japanese Society of Alternatives to Animal Experiments ,  Bioperoxide Association ,  The Pharmaceutical Society of Japan ,  Society Cosmetic Chemists Japan ,  Japan Cosmetic Science Society
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