Nakamura Megumi

ナカムラメグミ | Nakamura Megumi

Affiliation and department：
Job title： Senior Assistant Professor
Homepage URL (2)： http://db.tohoku.ac.jp/whois/detail/c0924c9d7c919cfe658aedd2e01c9ce0.html , http://db.tohoku.ac.jp/whois/e_detail/c0924c9d7c919cfe658aedd2e01c9ce0.html

Research field (2)： Surgical dentistry , Oral medicine

Research keywords (7)： Bone healing process , Tooth germ transplantation , Effects of aging on oral tissues , Roles of osteoclasts in the process of bone development and healing , Expression of MMPs and ADAMTSs during development and aging , Developmnet of bone and teeth , Resorption of Meckel's cartilage

Research theme for competitive and other funds (11)：

2021 - 2024 GFPマウス歯胚移植における歯根膜再生メカニズムの解明
2018 - 2022 骨修復に破骨細胞は必要か:破骨細胞分化抑制モデルマウスを用いた実験的検討
2015 - 2019 Identification of ECM proteins that inhibit calcification in bone and dentin using matrix-assisted laser desorption/ionization imaging mass spectrometry
2015 - 2018 網羅的遺伝子解析を用いた破骨細胞分化抑制マウスにおける歯の萌出機序の解明
2012 - 2016 Analysis of bone healing process with the in vivo targeting system of NFkB decoy

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Papers (21)：

Mu-Chen Yang, Megumi Nakamura, Yoko Kageyama, Yohei Igari, Yasuyuki Sasano. Age-Related Gene and Protein Expression in Mouse Mandibular Condyle Analyzed by Cap Analysis of Gene Expression and Immunohistochemistry. Gerontology. 2023. 69. 11. 1295-1306
Yasuyuki SASANO, Alu KONNO, Megumi NAKAMURA, Akiko HENMI, Miyuki MAYANAGI, Mu-Chen YANG, Ikuko YAO. Visualization of the localization of phospholipids in developing rat teeth by matrix-assisted laser desorption/ionization imaging mass spectrometry. Biomedical Research. 2023. 44. 4. 173-179
Mu-Chen YANG, Megumi NAKAMURA, Miyuki MAYANAGI, Yasuyuki SASANO. Immunohistochemical characterization of the mandibular condyle for type I and II collagen, aggrecan, MMP-9, and MMP-13 in MMP-2-deficient mice. Biomedical Research. 2023. 44. 2. 65-72
Miyuki Mayanagi, Megumi Nakamura, Akiko Henmi, Yasuyuki Sasano. The visualization of the mineral and protein distribution in the same histological sections of rat calcified growth plate cartilage. Journal of Oral Biosciences. 2022
Yoko Kageyama, Megumi Nakamura, Yohei Igari, Satoshi Yamaguchi, Akiko Oguchi, Yasuhiro Murakawa, Yoshinori Hattori, Yasuyuki Sasano. Expression of matrix metalloproteinase-3 and -10 is up-regulated in the periodontal tissues of aged mice. Journal of Periodontal Research. 2022. 57. 4. 733-741

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MISC (30)：

菅野千春, 中村恵, 大方広志, 山本寿則, 笹野泰之. マウス実験的歯周炎におけるMMP9とMMP13の発現に関する検討. 日本歯周病学会会誌. 2023. 65. 秋季特別. 128-128
中村恵, Yang Mu-Chen, 山口哲史, 大方広志, 笹野泰之. マウス実験的歯周炎モデルを用いた加齢と炎症が及ぼす歯槽骨吸収への影響. 日本歯周病学会会誌. 2023. 65. 秋季特別. 129-129
中村恵, Yang Mu-Chen, 笹野泰之. マウス実験的歯周炎における歯槽骨吸収に対する加齢と炎症の影響. Journal of Oral Biosciences Supplement. 2023. 2023. [P2-12]
中村恵, Yang Mu-Chen, 笹野泰之. 骨形成の場を整える吸収系細胞の検討下顎の発生過程において石灰化組織吸収に寄与する細胞(Cells responsible for resorption of calcified tissues during mandibular development). Journal of Oral Biosciences Supplement. 2022. 2022. 64-64
楊牧蓁, 中村恵, 笹野泰之. 高齢マウスの顎関節における網羅的遺伝子解析(Whole transcriptome profiling and immunohistochemical analysis in the TMJ condyle of aged mice). Journal of Oral Biosciences Supplement. 2021. 2021. 121-121

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Patents (1)：

三次元画像処理装置、三次元画像処理方法及びプログラム

Lectures and oral presentations (48)：

マウス実験的歯周炎モデルを用いた加齢と炎症が及ぼす歯槽骨吸収への影響
(第66回秋季日本歯周病学会学術大会 2023)
マウス実験的歯周炎におけるMMP9とMMP13の発現に関する検討
(第66回秋季日本歯周病学会学術大会 2023)
マウス実験的歯周炎における歯槽骨吸収に対する加齢と炎症の影響
(第65回歯科基礎医学会学術大会 2023)
Immunohistochemical localization of MMP-9, MMP-13, and extracellular matrix proteins in the mandibular condyle of MMP-2-deficient mice
(2023)
Whole transcriptome analysis with CAGE revealed that MMPs-3, -9, and -13 were differentially expressed in the mandibular condyle of aged mice
(2023)

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Education (2)：

2001 - 2005 Tohoku University Graduate School, Division of Dental Research
1995 - 2001 Tohoku University Faculty of Dentistry 歯学科

Professional career (1)：

博士(歯学) (Tohoku University)

Work history (5)：

2021/12 - 現在 Tohoku University Graduate School of Dentistry Craniofacial Development and Tissue Biology Senior Assistant Professor
2019/04 - 2021/11 Tohoku University Graduate School of Dentistry
2007/04 - 2019/03 Tohoku University Graduate School of Dentistry Division of Craniofacial Development and Regeneration Assistant professor
2006/04 - 2007/03 Tohoku University Graduate School of Dentistry
2005/04 - 2006/03 東北大学歯学部付属病院口腔外科研修医

Committee career (1)：

2023/04 - 現在日本解剖学会認定解剖組織技術者資格審査委員会委員

Association Membership(s) (4)：

Japanese Association of Anatomists(2008/06-) , 歯科基礎医学会(2004/07-) , 日本口腔外科学会(2002/12-2009/04) (2017/4-) , JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY

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