Rchr
J-GLOBAL ID:200901051407015187   Update date: Mar. 02, 2024

Yosuke Nakazawa

ナカザワ ヨウスケ | Yosuke Nakazawa
Affiliation and department:
Job title: Assistant Professor/Senior Assistant Professor
Research field  (1): Ophthalmology
Research theme for competitive and other funds  (9):
  • 2023 - 2026 Analysis of the mechanism of presbyopia and development of animal models
  • 2020 - 2023 Roles for the TRPVs channels in the lens in the initiation of presbyopia
  • 2021 - 2022 Mechanobiological analysis of cell-basement membrane interaction during eye lens morphogenesis
  • 2020 - 2022 Roles for the mechanosensitive channels (TRPV1 and TRPV4) in the initiation of presb yopia and development of cataract
  • 2018 - 2019 老眼発症遅延薬の開発を見据えて:老眼発症メカニズムの解明と老眼モデル動物の開発
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Papers (80):
  • Murata T, Tago K, Miyata K, Moriwaki Y, Misawa H, Kobata K, Nakazawa Y, Tamura H, Funakoshi-Tago M. Suppression of Neuroinflammation by Coffee Component Pyrocatechol via Inhibition of NF-κB in Microglia. International journal of molecular sciences. 2023. 25. 1
  • Deguchi, S, Iwakami, A, Tujigiwa, M, Otake, H, Mano, Y, Yamamoto, N, Nakazawa, Y, Misra, M, Nagai, N. Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone. JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES. 2023. 9. 1. 44-44
  • Doki Y, Nakazawa Y, Sukegawa M, Petrova RS, Ishida Y, Endo S, Nagai N, Yamamoto N, Funakoshi-Tago M, Donaldson PJ. Piezo1 channel causes lens sclerosis via transglutaminase 2 activation. Experimental eye research. 2023. 237. 109719
  • Murata T, Ishiwa S, Lin X, Nakazawa Y, Tago K, Funakoshi-Tago M. The citrus flavonoid, nobiletin inhibits neuronal inflammation by preventing the activation of NF-κB. Neurochemistry international. 2023. 171. 105613-105613
  • Kana Aihara, Yosuke Nakazawa, Shun Takeda, Natsuko Hatsusaka, Takanori Onouchi, Noriko Hiramatsu, Mayumi Nagata, Noriaki Nagai, Megumi Funakoshi-Tago, Naoki Yamamoto, et al. Aquaporins contribute to vacuoles formation in Nile grass type II diabetic rats. Medical molecular morphology. 2023
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MISC (10):
  • Yumika Kuno, Yosuke Nakazawa. Ambient Temperature affects TRPV1 activity in lens Epithelial Cells. The Journal of the Japanese Society for Cataract Research. 2024. 36
  • Kana Aihara, Yosuke Nakazawa. Role of Aquaporins and Connexins in the Lens and Contribution to Cataract Development. The Journal of the Japanese Society for Cataract Research. 2024. 36
  • 中澤洋介, 多胡めぐみ, 田村悦臣. コーヒー摂取と白内障予防. 食と医療. 2023. 27. 40-46
  • 中澤洋介, 遠藤伸, 森下尚紀. alpha-グルコシルヘスペリジンの水晶体に対する機能と老眼サプリメントの可能性. 食と医療. 2022. 23. 59-65
  • 中澤洋介. 水晶体の構造特性と関連疾患予防薬の可能性. ファルマシア. 2022. 58. 11. 1051-1055
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Lectures and oral presentations  (113):
  • The physical changes by aging in the lens and treatment its related diseases.
    (日本薬学会第144年会 2024)
  • 基礎研究で老視に挑む!
    (第17回 眼抗加齢医学研究会 アップデートセミナー 2024)
  • 高温環境ではTRPV1チャネルの活性化を介して老視発症を早める
    (第2回日本老視学会 2024)
  • 動物モデルによる水晶体硬化機序と治療の可能性
    (第2回日本老視学会 2024)
  • Physiological modulation of the crystalline lens water transport changes the stiffness of the ex vivo non-decapsulated bovine lenses measured using a lens spin test system.
    (International conference on the Lens 2023 2023)
more...
Professional career (1):
  • 博士 (薬学)
Work history (5):
  • 2019/04 - 現在 Fuculty of Pharmacy, Keio University Senior Lecturer
  • 2012/04 - 2019/03 慶應義塾大学薬学部 助教
  • 2016/09 - 2017/08 The University of Auckland Faculty of Medical and Health Sciences Visiting Researcher
  • 2009/04 - 2012/03 慶應義塾大学薬学部 助手
  • 2005/04 - 2009/03 Faculity of pahrmacy, setsunan university 助手
Committee career (11):
  • 2022/04 - 現在 日本老視学会 理事
  • 2022/01 - 現在 Ocular Scientific Meeting 監事
  • 2021/11 - 現在 日本白内障学会 The Journal of The Japanese Society for Cataract Research, Editor-in-Chief
  • 2021/04 - 現在 日本眼薬理学会 評議員
  • 2019/07 - 現在 白内障学会 評議員
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Awards (15):
  • 2023/07 - 62nd Annula Meeting of the Japanese Society for Catarct Research 優秀演題賞 Verification of Piezo channels expression in the mouse lens
  • 2021/11 - Japanese Society for Cataract Research Best Presentation Award in Japanese Society for Cataract Research TRPV1 activation can prevents Posterior capsule opacification
  • 2019/11 - Japan Health Fundation 2019年度 助成研究発表会 優秀賞
  • 2019/09 - 公益社団法人日本薬学会関東支部 日本薬学会2019年度関東支部 奨励賞 抗白内障薬/抗老眼薬の創製を見据えて:水晶体透明性維持機構の解明と疾患予防の基盤研究
  • 2019/07 - Vector Laboratories社 Imaging competion Winner 2019 lens E10 section
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