Takahashi Shigeru

タカハシシゲル | Takahashi Shigeru

Affiliation and department：

Research field (3)： Molecular biology , Environmental effects of chemicals , Environmental impact assessment

Research keywords (4)： stress response , environmental stress response , 分子生物学 , Molecular Biology

Research theme for competitive and other funds (16)：

2011 - 2013 N-terminal hydrophobic amino acids of ATF5 protein confer IL-1b-induced stabilization, and responsible for the suppression of the serum amyloid A1 (SAA1) ans SAA2 gene expression
2007 - 2008 NMD mediated new stress response mechanism
2006 - 2007 Cellular differentiation from human lung epithelial progenitor cells to pulmonary nuroendocrine cells
2004 - 2005 Choromatin modifier-associated cellular differentiation of pulmonary epithelial cells to neuroendocrine cells
2004 - 2005 Effect of environmental stress responsive transcription factor ATF5 on adipogenesis

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Papers (58)：

Chiharu Ishii, Haruo Nakano, Riko Higashiseto, Yusaku Ooki, Mariko Umemura, Shigeru Takahashi, Yuji Takahashi. Nescient helix-loop-helix 1 (Nhlh1) is a novel activating transcription factor 5 (ATF5) target gene in olfactory and vomeronasal sensory neurons in mice. Cell and tissue research. 2024. 396. 1. 85-94
Haruo Nakano, Ayano Hata, Usato Ishimura, Ryo Kosugi, Eina Miyamoto, Kota Nakamura, Takumi Muramatsu, Moe Ogasawara, Motohiro Yamada, Mariko Umemura, et al. Activating transcription factor 5 (ATF5) controls intestinal tuft and goblet cell expansion upon succinate-induced type 2 immune responses in mice. Cell and tissue research. 2023. 393. 2. 343-355
Haruo Nakano, Shiori Kawai, Yusaku Ooki, Tomoki Chiba, Chiharu Ishii, Takumi Nozawa, Hisako Utsuki, Mariko Umemura, Shigeru Takahashi, Yuji Takahashi. Functional validation of epitope-tagged ATF5 knock-in mice generated by improved genome editing of oviductal nucleic acid delivery (i-GONAD). Cell and tissue research. 2021. 385. 1. 239-249
Haruo Nakano, Yoshitaka Iida, Takahiro Murase, Natsuki Oyama, Mariko Umemura, Shigeru Takahashi, Yuji Takahashi. Co-expression of C/EBPγ and ATF5 in mouse vomeronasal sensory neurons during early postnatal development. Cell and tissue research. 2019. 378. 3. 427-440
Young Sook Yun, Yukari Takeda, Haruhiko Fukaya, Hiroyuki Fuchino, Nobuo Kawahara, Shigeru Takahashi, Yuji Takahashi, Hideshi Inoue. A new ent-norabietant diterpenoid from roots of Euphorbia lathyris L. Tetrahedron Letters. 2018. 59. 29. 2813-2815

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MISC (50)：

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Education (3)：

1989 - 1992 University of Tsukuba
1987 - 1989 University of Tsukuba
1983 - 1987 University of Tsukuba

Professional career (2)：

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Work history (6)：

2007/04 - 現在 Tokyo University of Pharmacy and Life Sciences School of Life Science
2004/03 - 2007/03 Tokyo University of Pharmacy and Life Sciences School of Life Science Assosiate professor
1994/04 - 2004/02 Tokyo University of Pharmacy and Life Sciences School of life science assistant professor
2002/05 - 2003/03 Scripps Research Institute
2001/04 - 2002/04 Salk Institute of Biological Studies

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Association Membership(s) (3)：

日本農芸化学会 , 日本分子生物学会 , 日本生化学会

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