Research theme for competitive and other funds (25):
2018 - 2022 Creation of mammalian oocytes with high fertility by spatiotemporal regulation of the function of mitochondria
2018 - 2022 生命機能の光制御のための機能性光増感ペプチドの開発
2016 - 2019 Live imaging of microRNA by intracellular-invasion peptide nucleic acid beacon
2017 - 2019 ケージドアミノアシルtRNAによる初期胚における翻訳の時空間的制御
2015 - 2017 細胞内におけるRNA分解の観測法の開発とストレス応答研究への応用
2014 - 2016 光増感剤修飾分子を用いたPCI の分子科学
2013 - 2016 PCDR技術による細胞機能の光制御
2013 - 2015 Sonochemical internalization法の確立
2012 - 2014 光増感によるエンドソーム脱出の分子科学
2011 - 2013 RNAが引き起こす細胞内イベントの細胞周期依存性の解析
2009 - 2012 CLIP-RNAi法の開発と応用
2008 - 2010 拡張型蛋白質合成系を含む細胞システムの構築
2008 - 2010 RNAi創薬を目指したRNAデリバリー技術の開発
2007 - 2009 人工核酸によるRNAの検出と精製
2006 - 2008 RNAの新規細胞内導入法の開発と応用
2006 - 2008 非天然アミノ酸含有タンパク質の無細胞及び細胞モデル系での発現
2007 - 2008 New development in study of mitochondrial translation system of theparasitic nematode
2005 - 2007 生細胞中での蛋白質の部位特異的蛍光標識法の開発
2003 - 2007 Chemical Expansion of the Central Dogma towards Synthetic Microorganisms
2005 - 2006 Study of parasite mitochondrial translation system which have truncated functional RNAs
2003 - 2004 Study of nematode mitochondrial translation system using parasitic nematodes
2002 - 2003 異常tRNAを用いた翻訳系
2002 - 2003 Elucidation of basic principle in genetic information translation system by using the specialty of animal mitochondria
2001 - 2002 伸長因子EF-TuによるTアームを欠くtRNAの認識機構
1999 - 2001 Elucidation of the construction principle of the mitochondria translation system by means of structural biology
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Papers (108):
Taufik F.N. Hakim, Kazunori Watanabe, Shomu Fujimoto, Mizuki Kitamatsu, Takashi Ohtsuki. Self-assembly of Peptide Amphiphiles with Alkyl Groups for siRNA Delivery. Chemistry Letters. 2023
Yuka Ikawa, Takuya Wakai, Hiroaki Funahashi, Tet Htut Soe, Kazunori Watanabe, Takashi Ohtsuki. Photo-dependent cytosolic delivery of shRNA into a single blastomere in a mouse embryo. Scientific reports. 2023. 13. 1. 13050-13050
Myat Thu, Kouta Yanai, Hajime Shigeto, Shohei Yamamura, Kazunori Watanabe, Takashi Ohtsuki. FRET probe for detecting two mutations in one EGFR mRNA. Analyst. 2023. 148. 11. 2626-2632
Akinari Bando, Kazunori Watanabe, Takashi Ohtsuki. Photochemical internalizationに基づく光依存的細胞質内RNA導入法の副作用低減. The Journal of Japan Society for Laser Surgery and Medicine. 2023. 44. 1. 62-68