Tohyama Chiharu

• 化学物質の健康影響とそのメカニズムの解明
• 重金属・ダイオキシン・環境ホルモンの毒性メカニズムの解明と 健康リスクアセスメント
• 1. Elucidation of mechanism of toxicity by heavy metals dioxins and environmental endocrine disrupters and development of detection methods 2. Physiological and toxicological significance of metallothionein

• K Inouye, T Ito, H Fujimaki, Y Takahashi, T Takemori, XQ Pan, C Tohyama, K Nohara. Suppressive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the high-affinity antibody response in C57BL/6 mice. TOXICOLOGICAL SCIENCES. 2003. 74. 2. 315-324
• T Moriguchi, H Motohashi, T Hosoya, O Nakajima, S Takahashi, S Ohsako, Y Aoki, N Nishimura, C Tohyama, Y Fujii-Kuriyama, et al. Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003. 100. 10. 5652-5657
• N Nishimura, J Yonemoto, Y Miyabara, M Sato, C Tohyama. Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. ENDOCRINOLOGY. 2003. 144. 5. 2075-2083
• M Kakeyama, H Sone, Y Miyabara, C Tohyama. Perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters activity-dependent expression of BDNF mRNA in the neocortex and male rat sexual behavior in adulthood. NEUROTOXICOLOGY. 2003. 24. 2. 207-217
• Metallothionein deficiency enhances skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate in metallothionein-null mice. Carcinogenesis. 2003. 24 (6): 1123-1132

ｍore...

• The University of Tokyo
• Rochester大学大学院
• University of Tokyo
• University of Rochester Graduate School

• Doctor of Philosophy : Doctor of Medical Sciences

• 2005/01 - The Universtiy of Tokyo Professor
• 2001 - :独立行政法人・国立環境研究所領域長
• 1994 - :国立環境研究所部長
• 1994 - Director, National Institute for Environmental Studies
• 1981 - :国立公害研究所研究員
1981 - Researcher, National Institute for Environmental Studies

• 2003 - 2005 日本衛生学会 編集委員長

• 2010/05 - Japan Society of Hygiene Achievement Award
• 2009/10 - Japan Socity of Risk Analysis Achievement Award
• 1998年 日本衛生学会奨励賞
• Hygiene
• The Award for Encouragement of the Japanese Society for

Society of Toxicology ,  日本内分泌攪乱化学物質学会 ,  日本生化学会 ,  日本産業衛生学会 ,  日本衛生学会 ,  日本リスク学会 ,  環境科学会 ,  The Society for Risk Analysis : Japan-Section ,  The Japanese Society for Hygiene ,  The Japanese Biochemical Society ,  Society of Toxicology ,  Society of Environmental Science ,  Japan Society of Endocrine Disrupters Research ,  Japan Society for Occupational Health