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J-GLOBAL ID:200901052575762385   Update date: Apr. 17, 2024

KONISHI Yoshiyuki

コニシ ヨシユキ | KONISHI Yoshiyuki
Affiliation and department:
Job title: Professor
Research field  (5): Developmental biology ,  Neuroanatomy and physiology ,  Cell biology ,  Molecular biology ,  Neuroscience - general
Research keywords  (8): 神経科学 ,  神経化学 ,  細胞生物学 ,  分子生物学 ,  Neuroscience ,  Neurochemistry ,  Cell Biology ,  Molecular Biology
Research theme for competitive and other funds  (12):
  • 2020 - 2023 軸索内に停止型ミトコンドリアを一様に分布させる機構の解明
  • 2017 - 2020 Function of tubulin modification as a signal to discriminate compartments in axons
  • 2014 - 2016 軸索パターンの構築において空間情報伝達と構造的安定化を司る分子反応の解明
  • 2011 - 2015 微小管修飾を介した神経細胞の形態機能制御
  • 2012 - 2014 細胞内局所での分子反応と軸索変性との関連を明らかにする
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Papers (54):
  • Yashuang Ping, Kenji Ohata, Kenji Kikushima, Takumi Sakamoto, Ariful Islam, Lili Xu, Hengsen Zhang, Bin Chen, Jing Yan, Fumihiro Eto, et al. Tubulin Polyglutamylation by TTLL1 and TTLL7 Regulate Glutamate Concentration in the Mice Brain. Biomolecules. 2023. 13. 5. 784-784
  • Takahiro Tsuji, Tomoya Murase, Yoshiyuki Konishi, Masaru Inatani. Optic Nerve Injury Enhanced Mitochondrial Fission and Increased Mitochondrial Density without Altering the Uniform Mitochondrial Distribution in the Unmyelinated Axons of Retinal Ganglion Cells in a Mouse Model. International journal of molecular sciences. 2023. 24. 5
  • Chiaki Imanaka, Satoshi Shimada, Shino Ito, Marina Kamada, Tokuichi Iguchi, Yoshiyuki Konishi. A model for generating differences in microtubules between axonal branches depending on the distance from terminals. Brain Research. 2023. 1799. 148166-148166
  • Nozomu Matsumoto, Ikuma Hori, Masashi K Kajita, Tomoya Murase, Wataru Nakamura, Takahiro Tsuji, Seiji Miyake, Masaru Inatani, Yoshiyuki Konishi. Intermitochondrial signaling regulates the uniform distribution of stationary mitochondria in axons. Molecular and cellular neurosciences. 2022. 119. 103704-103704
  • Saga, Yuya, Hatakenaka, Yudai, Matsumoto, Miho, Yoshioka, Yuri, Matsumura, Shinichi, et al. Neuroprotective effects of aromatic turmerone on activity deprivation-induced apoptosis in cerebellar granule neurons. NEUROREPORT. 2020. 31. 18. 1302-1307
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MISC (13):
  • Masashi K. Kajita, Yoshiyuki Konishi, Tetsuhiro S. Hatakeyama. Active thermodynamic force driven mitochondrial alignment. 2023
  • 小西慶幸. チロシン化,脱チロシン化. 生体の科学. 2018. 49. 4. 476-477
  • 堤 弘次, 久保 亜紀子, 高木 博, 赤津 裕康, 紺野 在, 宮本 裕子, 矢尾 育子, 江川 潔, 佐藤 尚武, 久保 亮治, et al. 多系統萎縮症患者脳ではγ-tubulinが減少しており、人工的γ-tubulin 2減少モデル動物は多系統萎縮症様の神経変性と運動失調を発症する(γ-Tubulins are decreased in the MSA patient brains and γ-tubulin 2-deficient mouse displays MSA-like neurodegeneration and ataxia). 神経化学. 2011. 50. 2-3. 163-163
  • 木村 芳滋, 倉部 誠也, 池上 浩司, 堤 弘次, 小西 慶幸, Kaplan Oktay I, 國友 博文, 飯野 雄一, Blacque Oliver E, 瀬藤 光利. チューブリンのポリグルタミン酸化修飾は双方向性に制御され、線虫(C.elegans)の知覚行動に必要である(Tubulin polyglutamylation is regulated by a bidirectional enzymatic system and is required for sensory behaviors of C. elegans). 神経化学. 2010. 49. 2-3. 479-479
  • Yoshishige Kimura, Nobuya Kurabe, Koji Ikegami, Koji Tsutsumi, Yoshiyuki Konishi, Oktay I. Kaplan, Hirofumi Kunitomo, Yuichi Iino, Oliver E. Blacque, Mitsutoshi Setou. Tubulin polyglutamylation is regulated by a bidirectional enzymatic system and is required for sensory behaviors of C. elegans. NEUROSCIENCE RESEARCH. 2010. 68. E58-E58
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Books (1):
  • 遺伝子工学実験ノート(下巻)
    羊土社 2010
Lectures and oral presentations  (46):
  • Intracellular systems regulating the dynamics and distributions of axonal mitochondria and presynaptic vesicles
    (14th International Symposium on Nanomedicine (ISNM) 2021)
  • バイオイメージングによる神経細胞の形態調節機構の解析
    (日本農芸化学会中部支部 第189回例会 2021)
  • チューブリンコードを介した神経細胞の形態制御とその撹乱
    (第6回北陸エピジェネティクス研究会 2019)
  • 軸索におけるミトコンドリアの配置制御
    (北陸合同バイオシンポジウム 2019)
  • Distribution regularity of mitochondria and en passant presynaptic sites along axon in cerebellar granule neurons
    (Neuroscience 2019, 49th annual meeting of the Society for Neuroscience, Chicago, IL 2019)
more...
Education (5):
  • 1997 - 2000 Chiba University Graduate School, Division of Science and Technology
  • 1997 - 2000 Chiba University
  • 1995 - 1997 Chiba University Graduate School, Division of Natural Science
  • 1995 - 1997 Chiba University
  • 1991 - 1995 Chiba University
Work history (8):
  • 2019/04 - 現在 福井大学学術研究院工学系部門 教授
  • 2011/04 - 2019/03 Graduate School of Engineering Associate Professor
  • 2008/11 - 2011/03 Molecular Imaging Frontier Research Center, Hamamatsu University School of Medicine Associate Professor
  • 2006/04 - 2008/01 Mitsubishi Kagaku Institute of Life Sciences Senior Researcher
  • 2004/07 - 2006/03 Center for Molecular Medicine, Jichi Medical School Assistant Professor
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Committee career (1):
  • 2011/04/01 - 2021/03/31 日本神経化学会 評議員
Awards (2):
  • 2010 - The Award for Distinguished Young Investigator of Japanese Society for Neurochemistry
  • 2000 - Harvard School of Public Health, Taplin fellowship
Association Membership(s) (7):
日本神経化学会 ,  日本神経化学会 ,  日本神経化学会 ,  盛和スカラーズソサエティ ,  日本分子生物学会 ,  日本細胞生物学会 ,  日本神経科学会
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