Rchr
J-GLOBAL ID：200901053713458311
Update date: Jul. 06, 2022
Hasegawa Akiko
ハセガワアキコ | Hasegawa Akiko
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Affiliation and department：
Hyogo College of Medicine Faculty of Medicine
About Hyogo College of Medicine Faculty of Medicine
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Detailed information
Job title：
Lecturer
Homepage URL (1)：
http://www.hyo-med.ac.jp/research_facilities/
Research field (4)：
Obstetrics and gynecology
, Pharmacology
, Pharmaceuticals - health and biochemistry
, Developmental biology
Research keywords (2)：
Reproductive Biology, Reproductive Medicine
, Reproductive Biology
Research theme for competitive and other funds (12)：
2011 - 2013 血管新生統御を基盤としたがん・循環器病治療法の開発研究拠点形成
2007 - 2009 卵巣組織の凍結保存と卵母細胞の培養系での成熟・受精・胚発生に関する研究
2004 - 2009 配偶子形成において特異的に発現する遺伝子の同定とタンパクの機能解析および生殖補助医療への応用
2004 - 2006 成熟精子に存在する特異抗原CD52の鼻腔免疫による避妊ワクチンの開発
2003 - 2005 精子と卵透明帯の種特異認識機構に関する分子生物学的検討
1999 - 2004 ヒトの配偶子形成と受精現象に関与し妊娠成立の鍵となる遺伝子群の探索と機能の解明
2001 - 2002 ヒト透明帯タンパクの遺伝子組み換え法による生産と避妊ワクチンへの応用
2000 - In-vitro growth and maturation of oocytes from preantral ovarian follicles
Role of CD52 for reproduction
Contribution of zona protein to oocyte grwoth
Sperm-egg interactions
Development of contraceptive vaccines by using gamete-related antigens
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Papers (4)：
Hiroshi Yoshitake, Mitsuaki Yanagida, Mayuko Maruyama, Kenji Takamori, Akiko Hasegawa, Yoshihiko Araki. Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis. JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2011. 90. 2. 202-213
Koji Koyama, Akiko Hasegawa, Shinji Komori. Functional aspects of CD52 in reproduction. JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2009. 83. 1-2. 56-59
Yohei Shirai, Hiroshi Yoshitake, Mayuko Maruyama, Kenji Takamori, Hideoki Ogawa, Akiko Hasegawa, Yoshihiko Araki. Distribution of Molecular Epitope for Ts4, an Anti-Sperm Auto-Monoclonal Antibody in the Fertilization Process. JOURNAL OF REPRODUCTION AND DEVELOPMENT. 2009. 55. 3. 240-246
Akiko Hasegawa, Takashi Takenobu, Hiroyuki Kasumi, Shinji Komori, Koji Koyama. CD52 is synthesized in cumulus cells and secreted into the cumulus matrix during ovulation. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2008. 60. 3. 187-191
MISC (123)：
Giannina Calongos, Akiko Hasegawa, Shinji Komori, Koji Koyama. Harmful effects of anti-zona pellucida antibodies in folliculogenesis, oogenesis, and fertilization. JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2009. 79. 2. 148-155
Hiroshi Yoshitake, Yohei Shirai, Yasuhiro Mochizuki, Hiroko Iwanari, Hiroshi Tsubarnoto, Koji Koyama, Kenji Takamori, Hideoki Ogawa, Akiko Hasegawa, Tatsuhiko Kodama, et al. Molecular diversity of TEX101, a marker glycoprotein for germ cells monitored with monoclonal antibodies: Variety of the molecular characteristics according to subcellular localization within the mouse testis. JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2008. 79. 1. 1-11
Akiko Hasegawa, Takashi Takenobu, Hiroyuki Kasumi, Shinji Komori, Koji Koyama. CD52 is synthesized in cumulus cells and secreted into the cumulus matrix during ovulation. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2008. 60. 3. 187-191
Giannina Calongos, Akiko Hasegawa, Shinji Komori, Koji Koyama. Comparison of urinary and recombinant follicle-stimulating hormone in in vitro growth, maturation, and fertilization of mouse preantral follicles. FERTILITY AND STERILITY. 2008. 89. 5. 1482-1489
K. Ito, A. Hasegawa, S. Komori, K. Koyama. Biochemical property and immunogenicity of mouse male reproductive tract CD52 (mrt-CD52). JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2007. 75. 1. 32-39
ｍore...
Books (9)：
Oocytology
Kyoto University Press 2011 ISBN:9784876989249
生命の誕生に向けて 第2版: 日本哺乳動物卵子学会
2009 ISBN:9784874021699
図説よくわかる臨床不妊症学 生殖補助医療編
中外出版 2007
生命の誕生に向けて 生殖補助医療(ART) 胚培養の理論と実際
日本哺乳動物卵子学会 2005 ISBN:4874021107
進化していく体外受精Progress(共著)
メジカルビュー社 2005
ｍore...
Education (2)：
- 1977 Osaka University
- 1977 Osaka University Graduate School, Division of Pharmaceutical Sciences
Professional career (2)：
Ph.D (Hyogo College of Medicine)
M.Sc (Osaka University)
Committee career (4)：
2003 - 2009 日本生殖免疫学会 評議員
1998 - 2009 日本受精着床学会 評議員
1991 - 2009 日本哺乳動物卵子学会 評議員
- 2006 日本生殖医学会 評議員
Awards (4)：
2007 - 第10回国際生殖免疫学会"Outstanding Poster Award"
2005 - 第57日本産科婦人科学会グッドプレゼンテーション賞
2003 - ヨーロッパ生殖免疫学会“Best Abstract Prize”
2003 - Best Abstract Prize (European Society for Reproductive and Developmental Immunology)
Association Membership(s) (8)：
米国生殖免疫学会
, 国際生殖免疫学会
, 日本哺乳動物卵子学会
, 日本受精着床学会
, 日本生殖免疫学会
, 日本生殖医学会
, 日本産科婦人科学会
, 日本免疫学会
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