Domae Eisuke

ドウマエエイスケ | Domae Eisuke

Affiliation and department：

Research field (2)： Community dentistry , Oral medicine

Research keywords (3)： Vγ9Vδ2 T-cells , Oral squamous cell carcinoma (OSCC) , Candidalysin

Research theme for competitive and other funds (10)：

2023 - 2026 Development of oral cancer immunotherapy based on cancer cell-specific induction of non-peptide antigens
2022 - 2026 免疫チェックポイント阻害を応用したヒトγδT細胞による口腔癌免疫療法の開発
2022 - 2025 C. albicans由来新規病原因子カンジダリシンの作用点の解明
2018 - 2022 Augmenting human gamma delta T cell-based immunotherapy against oral cancer by targeting nutritional genomics
2018 - 2022 Effect of the hydroxamic acid class of inhibitors on osteoclast differentiation

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Papers (25)：

Eisuke Domae, Aiko Kamada, Yoshihiro Yoshikawa, Takashi Ikeo. Heparin interacts with candidalysin and neutralizes its cytotoxicity to oral epithelial cells. Journal of oral biosciences. 2023. 65. 2. 206-210
Yoshihiro Yoshikawa, Atsushi Tamura, Susumu Tsuda, Eisuke Domae, Shunyao Zhang, Nobuhiko Yui, Takashi Ikeo, Tatsuya Yoshizawa. Calcium phosphate-adsorbable and acid-degradable carboxylated polyrotaxane consisting of β-cyclodextrins suppresses osteoclast resorptive activity. Dental Materials Journal. 2022. 41. 4. 624-632
Mariko Hanaoka, Eisuke Domae. IL-1α released from oral epithelial cells upon candidalysin exposure initiates an early innate epithelial response. International Immunology. 2021. 33. 3. 161-170
Tsuda Kenji, Kamada Aiko, Yoshikawa Yoshihiro, Domae Eisuke, Nishiura Aki, Matsumoto Naoyuki. ヒト歯髄におけるシンデカンの役割(The Role of Syndecans in the Human Dental Pulp). Journal of Oral Tissue Engineering. 2020. 18. 2. 55-62
Yuya Hirai, Eisuke Domae, Yoshihiro Yoshikawa, Keizo Tomonaga. Differential roles of two DDX17 isoforms in the formation of membraneless organelles. Journal of Biochemistry. 2020. 168. 1. 33-40

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MISC (33)：

吉川美弘, 津田進, 堂前英資, 池尾隆. カルボキシ基を修飾した酸分解性ポリロタキサンが破骨細胞に及ぼす影響. Journal of Oral Biosciences Supplement. 2023. 2023. [P2-06]
津田賢治, 鎌田愛子, 吉川美弘, 堂前英資, 西浦亜紀, 松本尚之. ヒト歯髄におけるシンデカンの役割. 日本再生歯科医学会誌. 2021. 19. 1. 21-21
花岡麻里子, 堂前英資. CandidalysinはIL-1α分泌を介して上皮細胞を活性化する. Journal of Oral Biosciences Supplement. 2020. 2020. 388-388
花岡麻里子, 堂前英資. Candidalysin-induced early innate epithelial response via released IL-1α. Journal of Oral Biosciences Supplement (Web). 2020. 2020
堂前英資, 花岡麻里子. Candidalysin-mediated activation of oral epithelial cells. 歯科医学. 2020. 83. 1. 26-27

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