Research field (5):
Molecular biology
, Pharmacology
, Pharmaceuticals - health and biochemistry
, Pathobiochemistry
, Medical biochemistry
Research theme for competitive and other funds (8):
2016 - 2019 Novel molecular mechanisms of actions of homocysteine, a risk factor of cardiovascular diseases
2016 - 2018 Mechanism of food rejection upon amino acid-unbalanced diet
2013 - 2018 Comprehensive study on environmental electrophiles-mediated signal transduction pathways regulated by reactive sulfur species
2013 - 2016 Functional relationship between metabolism of sulfur-containing amino acids and cardioprotection from ischemia-reperfusion injury
2011 - 2013 遺伝子改変マウスを利用したタンパク質チオール基化学修飾に基づく病態の検討
2010 - 2012 Pathophysiological analysis of acute muscle atrophy by failure of cysteine biosynthesis and development of its control strategy
2006 - 2007 PHYSIOLOGICAL ROLES OF THE CYSTEINE BIOSYNTHETIC PATHWAY AND PATHOSIS INDUCED BY ITS DYSFUNCTION
2003 - 2004 細胞膜受容体ノックアウトマウスを用いた生理活性リゾリン脂質の生理機能の解析
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Papers (107):
Qamarul Hafiz Zainol Abidin, Tomoaki Ida, Masanobu Morita, Tetsuro Matsunaga, Akira Nishimura, Minkyung Jung, Naim Hassan, Tsuyoshi Takata, Isao Ishii, Warren Kruger, et al. Synthesis of Sulfides and Persulfides Is Not Impeded by Disruption of Three Canonical Enzymes in Sulfur Metabolism. Antioxidants (Basel, Switzerland). 2023. 12. 4
UNOKI Takamitsu, AKIYAMA Masahiro, SHINKAI Yasuhiro, ISHII Isao, KUMAGAI Yoshito. RSS-producing enzyme CSE suppresses methylmercury-induced brain mercury accumulation and deleterious effects in mice. Annual Meeting of the Japanese Society of Toxicology. 2021. 48.1. P-24
Cytathionine β synthase is required to maintain glutathione hydropersulfide, a novel antioxidant molecule, in the murine lens
(10th World Congress for Microcirculation 2015)