Rchr
J-GLOBAL ID:200901056377075840   Update date: Mar. 28, 2024

Warita Katsuhiko

ワリタ カツヒコ | Warita Katsuhiko
Affiliation and department:
Job title: Professor
Research field  (5): Tumor biology ,  Veterinary medicine ,  Veterinary medicine ,  Veterinary medicine ,  Anatomy
Research keywords  (14): メバロン酸経路 ,  細胞運動 ,  がん転移 ,  evaluation of drug efficacy ,  drug sensitivity ,  tumor biology ,  statins ,  エピジェネティクス ,  内分泌撹乱物質 ,  内分泌 ,  epigenetics ,  endocrine disrupter ,  endocrinology ,  reproductive
Research theme for competitive and other funds  (21):
  • 2022 - 2026 妊娠母体炎症が惹起する児の脳-身体の双方向性制御機能の破綻
  • 2021 - 2025 Molecular mechanism for cell-fate conversion of non-pituitary tissue stem cells to gonadotrophs
  • 2019 - 2023 スタチンが効くがんを見極める予測因子の探索とがん転移抑制剤に向けたエビデンス構築
  • 2020 - 2023 がん代謝物に基づくスタチン適応がんの分類と微小腫瘍環境におけるスタチンの影響解析
  • 2020 - 2023 脂肪細胞分化抑制活性を示すコンドロイチン硫酸種の同定と機能の解明・脂肪量の制御
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Papers (90):
  • Nanami Irie, Kana Mizoguchi, Tomoko Warita, Mirai Nakano, Kasuga Sasaki, Jiro Tashiro, Tomohiro Osaki, Takuro Ishikawa, Zoltán N. Oltvai, Katsuhiko Warita. Repurposing of the Cardiovascular Drug Statin for the Treatment of Cancers: Efficacy of Statin-Dipyridamole Combination Treatment in Melanoma Cell Lines. Biomedicines. 2024. 12. 3. 698
  • Takuro Ishikawa, Nanami Irie, Jiro Tashiro, Tomohiro Osaki, Tomoko Warita, Katsuhiko Warita, Munekazu Naito. Comparison of the anticancer effects of various statins on canine oral melanoma cells. Veterinary and Comparative Oncology. 2024. 22. 1. 156-161
  • Kanako Irie, Ken-ichi Ohta, Hidetoshi Ujihara, Chihiro Araki, Kodai Honda, Shingo Suzuki, Katsuhiko Warita, Hikari Otabi, Haruki Kumei, Shinji Nakamura, et al. An enriched environment ameliorates the reduction of parvalbumin-positive interneurons in the medial prefrontal cortex caused by maternal separation early in life. Frontiers in Neuroscience. 2024. 17. 1308368
  • Ken-Ichi Ohta, Chihiro Araki, Hidetoshi Ujihara, Keizo Iseki, Shingo Suzuki, Hikari Otabi, Haruki Kumei, Katsuhiko Warita, Takashi Kusaka, Takanori Miki. Maternal separation early in life induces excessive activity of the central amygdala related to abnormal aggression. Journal of neurochemistry. 2023. 167. 6. 778-794
  • Danang Dwi CAHYADI, Katsuhiko Warita, Naoko Takeda-Okuda, Jun-ichi Tamura. Qualitative and quantitative analyses in sulfated glycosaminoglycans, chondroitin sulfate/dermatan sulfate, during 3T3-L1 adipocytes differentiation. Animal Science Journal. 2023. 94. e13894
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MISC (50):
  • 田代二朗, 杉浦曜大, 石川拓郎, 保坂善真, 割田克彦. コレステロール側鎖切断酵素の発現抑制ががん細胞の上皮間葉転換およびスタチン系薬剤感受性に及ぼす影響. 第165回日本獣医学会学術集会. 2022. 18
  • Statins Suppress SOAT1 Expression & Reduce Cholesterol Esterification in Statin-sensitive Lung Cancer Cells. 2022 World Conference on Lung Cancer of the International Association for the Study of Lung Cancer (WCLC 2022). 2022
  • Effectiveness of atorvastatin and SR-12813 combination in statin-resistant and statin-sensitive lung cancer cell lines. 2022
  • Identification of Optimal Internal Reference Gene to Analyze the Anticancer Effects of Statins in Lung Cancer Cells. 2022
  • T. Warita, K. Ohtani, T. Ishikawa, Z. N. Oltvai, K. Warita. Relationship between cholesterol synthesis in cancer cells and anticancer effect of statins. 2021 World Conference on Lung Cancer of the International Association for the Study of Lung Cancer (WCLC 2021). 2021
more...
Books (4):
  • 獣医組織学第8版
    学窓社 2020
  • 獣医組織学第7版
    学窓社 2017
  • カラーアトラス獣医解剖学 増補改訂第2版(下巻)
    緑書房 2016
  • Molecular cytogenetic aspects of sex differentiation anomalies in the field of obstetrics and gynecology
    Perspectives in Human Genetics 2008
Lectures and oral presentations  (2):
  • 発生由来の異なるがん細胞種のスタチン感受性に関する研究
    (第159回日本獣医学会学術集会(サテライトフォーラム)『上皮と間葉』を制御するキーファクター 〜発生・癌化の視点から〜 2016)
  • がん細胞のスタチン系薬剤感受性を決定する分子メカニズム-感受性マーカーの探索-
    (鳥取大学公開講演会 2015)
Professional career (1):
  • Ph.D. (Kobe University)
Work history (6):
  • 2023/04 - 現在 Tottori University Faculty of Agriculture School of Veterinary Medicine Division of Basic Veterinary Sciences Professor
  • 2015/04 - 2023/03 Tottori University School of Veterinary Medicine Associate Professor
  • 2014/04 - 2015/03 Kagawa University Faculty of Medicine Assistant Professor (reinstatement)
  • 2011/04 - 2014/03 University of Pittsburgh School of Medicine Postdoctoral fellow
  • 2007/04 - 2011/03 Kagawa University Faculty of Medicine Assistant Professor
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Committee career (2):
  • 2017 - 現在 Japanese Society of Veterinary Science Councilor
  • 2017 - 現在 日本獣医学会 評議員
Awards (1):
  • 2022/02 - 令和3年度科学研究業績表彰 Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells
Association Membership(s) (7):
日本ポリアミン学会 ,  The Japanese Cancer Association ,  The Japanese Society of Toxicologic Pathology ,  Japan Society of Endocrine Disrupter Research ,  The Japanese Society of Veterinary Science ,  Japanese Society for Epigenetics ,  The Japanese Association of Anatomists
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