Yamada Kazuya

ヤマダカズヤ | Yamada Kazuya

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://professors.matsumoto-u.ac.jp/yamada/ , http://professors.matsumoto-u.ac.jp/yamada/?lang=en

Research field (4)： Metabolism and endocrinology , Medical biochemistry , Molecular biology , Functional biochemistry

Research keywords (7)：分子栄養学 , 内分泌代謝学 , 分子生物学 , 生化学 , Endocrinology , Molecular Biology , Biochemistry

Research theme for competitive and other funds (24)：

2021 - 2024 血糖調節や健康の維持・増進における時計遺伝子の働きと臓器連関
2017 - 2020 Action mechanism of the insulin-inducible transcription factor and control of their gene expressions by diets and disease
2012 - 2015 Does the insulin-inducible transcription factor SHARP gene family involve in down-regulation of the blood glucose level?
2009 - 2011 Studies on high carbohydrate diet-induced transcription factors.
2006 - 2007 Analyses for mechanisms of progression of kidney diseases by proteinuria

2005 - 2006 Analysis of regulation of gene expression of an insulin-inducible transcription factor and its action mechanism

2003 - 2004 Regulation of gene expression and functional analysis of an insulin-inducible transcription factor

2002 - 2004 Molecular mechanism of transcriptional regulation of pyruvate kinase gene by glucose and insulin

2001 - 2002 Development of DNA micro-array for ultra-sensitive determination of endocrine disrupters in reproductive systems

2001 - 2002 Regulatory roles of a novel gonadotropin-inducible transcription factor (GIOT) for ovarian functions

2000 - 2001 炭水化物による遺伝子の転写促進機構の解析

1999 - 2001 Regulation of enzyme activity and gene expression of pyruvate kinase by dietary factors

1998 - 1999 Applied research for the development of gene diagnosis of ovarian dysfunction using a novel ovarian transcription factor GIOT.

1998 - 1999 Research on the role of a new hormone-inducible transcription factor GIOT for the ovarian function.

1997 - 1998 Regulation of transcription and splicing of pyruvate kinase isozyme genes

1998 - zinc-fingers and homeoboxes 1 ファミリーに関する研究

1997 - Studies on zinc-fingers and homeoboxes 1 (ZHX1)

1985 - 栄養素とホルモンによる遺伝子の転写調節機構の解析

1985 - Regulation of the gene expression of sugar- and lipid-metabolic enzymes in mammals.

転写因子の活性調節による血糖値の制御

ZHXスーパーファミリーの機能解析

蛋白質間相互作用の解析

Functional analysis of the ZHX superfamily

Analysis of protein-protein interactions

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Papers (117)：

三崎紀展, 林桃子, 髙木勝広, 山田一哉. ビタミンA誘導体による時計遺伝子・血糖上昇遺伝子の発現制御. 2021. 63. 7. 501-508
Momoko Hayashi, Toshinori Misaki, Sena Yoshida, Hiroshi Tokutake, Tomoki Aruga, Kazuya Yoda, Eri Kenmochi, Kaho Saito, Momo Togashi, Mai Nakano, et al. Retinoic acid stimulates transcription of the rat SHARP-2 gene via multiple pathways. The Journal of Biochemistry. 2021
Kosuke Asano, Akiko Tsukada, Yuki Yanagisawa, Mariko Higuchi, Katsuhiro Takagi, Moe Ono, Takashi Tanaka, Koji Tomita, Kazuya Yamada. Melatonin stimulates transcription of the ratphosphoenolpyruvate carboxykinasegene in hepatic cells. FEBS Open Bio. 2020. 10. 12. 2712-2721
Kosuke Asano, Akiko Tsukada, Katsuhiro Takagi, Kazuya Yamada. An insulin-inducible transcription factor, SHARP-1, represses transcription of the SIRT1 longevity gene. Biochemistry and biophysics reports. 2020. 22. 1-6
塚田晃子, 高木勝広, 山田一哉. インスリン誘導性 SHARP-1 遺伝子と SIRT1 長寿遺伝子の発現相関. NEW FOOD INDUSTRY. 2020. 62. 339-345

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MISC (29)：

大澤春彦, 田原康玄, 川村良一, 塚田晃子, 伊賀瀬道也, 大橋順, 山田亮, 高田康徳, 川本龍一, 斉藤功, et al. 日本人のGWASで同定された血中レジスチンを規定するSNPにおけるeffect sizeの検討. 糖尿病(Web). 2017. 60. Suppl
山田一哉, 髙木勝広, 浅野公介, 羽石歩美. 教育事業報告長野県松本美須々ヶ丘高等学校出張実験教室. 地域総合研究. 2016. 17. 1. 172-175
大澤春彦, 田原康玄, 川村良一, 塚田晃子, 伊賀瀬道也, 大橋順, 山田亮, 高田康徳, 川本龍一, 斉藤功, et al. レジスチン遺伝子プロモーターSNPとは独立して、新たな機能的SNPとして3'のrs1423096とrs10401670を同定した. 糖尿病. 2016. 59. Suppl.1. S-437
大澤春彦, 田原康玄, 川村良一, 塚田晃子, 伊賀瀬道也, 大橋順, 山田亮, 高田康徳, 川本龍一, 斉藤功, et al. レジスチン遺伝子プロモーターSNPとは独立して,新たな機能的SNPとして3’のrs1423096とrs10401670を同定した. 糖尿病(Web). 2016. 59. Suppl
H. Mifune, Y. Tajiri, K. Hara, S. Iwata, Y. Nishi, M. Kojima, K. Yamada. A disrupted rhythm of appetite-regulating hormone is relevant to abnormal feeding behaviour in high fat diet induced obese mice. DIABETOLOGIA. 2015. 58. S308-S308

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Patents (1)：

Books (8)：

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Professional career (2)：

Committee career (4)：

Awards (2)：

Association Membership(s) (3)：

日本生化学会 , The Japanese Biochemical Society , American Society for Biochemistry and Molecular Biology

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