Yamashita Takahiro

ヤマシタタカヒロ | Yamashita Takahiro

Affiliation and department：
Job title： Lecturer

Research field (3)： Functional biochemistry , Animals: biochemistry, physiology, behavioral science , Biophysics

Research theme for competitive and other funds (14)：

2016 - 2019 Analysis of uncharacterized phototransduction system in the vertebrate photoreceptor cells
2016 - 2019 Exploring of non-visual functions mediated by Opn5.
2015 - 2017 光で人工的細胞内情報伝達系を制御するシステムの構築
2013 - 2016 Analysis of the photoreceptive protein Opn5 found in invertebrates
2013 - 2016 Molecular and functional properties of Opn5

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Papers (65)：

Keiichi Kojima, Masataka Yanagawa, Yasushi Imamoto, Yumiko Yamano, Akimori Wada, Yoshinori Shichida, Takahiro Yamashita. Convergent mechanism underlying the acquisition of vertebrate scotopic vision. Journal of Biological Chemistry. 2024. 107175-107175
Keita Sato, Takahiro Yamashita, Hideyo Ohuchi. Mammalian type Opsin 5 preferentially activates G14 in Gq-type G proteins triggering intracellular calcium response. The Journal of biological chemistry. 2023. 105020-105020
Chihiro Fujiyabu, Keita Sato, Hideyo Ohuchi, Takahiro Yamashita. Diversification processes of teleost intron-less opsin genes. The Journal of biological chemistry. 2023. 104899-104899
Misao Mizuno, Keita Sato, Takahiro Yamashita, Kazumi Sakai, Yasushi Imamoto, Yumiko Yamano, Akimori Wada, Hideyo Ohuchi, Yoshinori Shichida, Yasuhisa Mizutani. Chromophore Structure in an Inactive State of a Novel Photosensor Protein Opn5L1: Resonance Raman Evidence for the Formation of a Deprotonated Adduct at the 11th Carbon Atom. The journal of physical chemistry. B. 2023. 127. 10. 2169-2176
Keita Sato, Yang Liu, Takahiro Yamashita, Hideyo Ohuchi. The medaka mutant deficient in eyes shut homolog exhibits opsin transport defects and enhanced autophagy in retinal photoreceptors. Cell and Tissue Research. 2023. 391. 2. 249-267

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MISC (14)：

Takahiro Yamashita, Akimori Wada. Discovery of novel microbial rhodopsin having unusual photoisomerization process. 2023. 97. 8. 374-377
酒井佳寿美, 山下高廣. サイクリックAMP濃度を光で一過的に操作する分子ツールの開発. 医学のあゆみ. 2022. 283. 11,12. 1080-1081
Molecular mechanism underlying color discrimination ability of frogs and geckos in the dark. 2022. 39. 3. 122-131
Creation of Photocyclic Vertebrate Visual Rhodopsin by Single Amino Acid Substitution. 2022. 62. 6. 351-353
山下高廣. G蛋白質共役受容体と紫外光受容蛋白質:紫外線をヒトは感じるか?. 脳神経内科. 2021. 94. 476-481

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Books (5)：

動物学の百科事典
丸善出版 2018
光と生命の事典
朝倉書店 2016
Evolution and Senses
Springer 2013
生き物たちのつづれ織り上
京都大学学術出版会 2012
動物の多様な生き方1;見える光、見えない光
共立出版 2009

Education (2)：

- 2002 Kyoto University
- 2002 Kyoto University Graduate School, Division of Natural Science Department of Biophysics

Professional career (1)：

Doctor of Science (Kyoto University)

Awards (3)：

2014 - 日本光生物学協会奨励賞
2002 - 日本生化学会JB論文賞
2002 - The JB Prize of the Japanese Biochemical Society

Association Membership(s) (7)：

日本生化学会 , 日本生物物理学会 , 日本動物学会 , The Japanese Biochemical Society , Society of Evolution Studies of Japan , The Biophysical Society of Japan , The Zoological Science of Japan

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