Rchr
J-GLOBAL ID:200901056742105583   Update date: Mar. 22, 2024

Tohkin Masahiro

トウキン マサヒロ | Tohkin Masahiro
Affiliation and department:
Job title: 教授
Homepage URL  (1): http://www.phar.nagoya-cu.ac.jp/hp/dse/
Research field  (3): Pharmacology ,  Clinical pharmacy ,  Pharmaceuticals - health and biochemistry
Research keywords  (4): Biomarker ,  大規模医療情報 ,  副作用 ,  国際共同治験
Research theme for competitive and other funds  (7):
  • 2021 - 2024 ネットワークメタ解析手法を用いた新規抗リウマチ薬の有効性と安全性の比較
  • 2018 - 2021 Efficacy and safety evaluation of new anti-diabetic drug by analyzing the claim database
  • 2014 - 2017 Effect of perioperative pharmacotherapy by using DPC data
  • 2011 - 2013 The effectiveness of risk communication regarding drug safety information: A nationwide survey by the Japanese public health insurance claims data
  • 1999 - 2001 IDENTIFICATION OF NUCLEAR FACTOR THAT ACTIVATED THE XRE-MEDIATED GENE TRANSCRIPTION
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Papers (145):
  • Takashi Watanabe, Kaori Ambe, Masahiro Tohkin. Streamlining Considerations for Safety Measures: A Predictive Model for Addition of Clinically Significant Adverse Reactions to Japanese Drug Package Inserts. Biological & pharmaceutical bulletin. 2024. 47. 3. 611-619
  • Takashi Watanabe, Kaori Ambe, Masahiro Tohkin. Predicting the Addition of Information Regarding Clinically Significant Adverse Drug Reactions to Japanese Drug Package Inserts Using a Machine-Learning Model. Therapeutic innovation & regulatory science. 2023
  • Miho Murashima, Kaori Ambe, Yuka Aoki, Takahisa Kasugai, Tatsuya Tomonari, Minamo Ono, Masashi Mizuno, Masahiro Tohkin, Takayuki Hamano. Epidemiology and predictors of hyponatremia in a contemporary cohort of patients with malignancy: a retrospective cohort study. Clinical Kidney Journal. 2023. sfad189
  • 島田 裕脩, 家田 維哉, 坂部 彩, 頭金 正博. 有害事象自発報告データベースを用いた直接経口抗凝固薬による中枢神経系出血性有害事象に対するプロトンポンプ阻害薬併用の影響に関する解析. 医療薬学. 2023. 49. 6. 231-240
  • Kaori Ambe, Ayu Akita, Jie Wei, Yuka Yoshii, Mayu Onishi, Masahiro Tohkin. Comparison of Efficacy and Safety of Direct Oral Anticoagulants and Warfarin between Patients in Asian and Non-Asian Regions: A Systematic Review and Meta-Regression Analysis. Clinical pharmacology and therapeutics. 2023. 113. 6. 1240-1250
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MISC (110):
  • 濱上敦史, 土井更良, 安部賀央里, 頭金正博. Development of prediction model for cholestatic Drug-Induced Liver Injury using JAPIC AERS and machine learning. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 青木優佳, 安部賀央里, 頭金正博, 村島美穂, 濱野高行, 和知野千春, 和知野千春, 木村和哲, 日比陽子, 日比陽子, et al. 電子カルテ情報と機械学習を活用したシスプラチン誘発性急性腎障害の予測モデルの構築. 日本臨床薬理学会学術総会抄録集(Web). 2023. 44th
  • 木下啓, 安部賀央里, 山田隆志, 足利太可雄, 頭金正博. Attempt to establish the machine learning model for predicting intensity of skin sensitization assessment for practical use. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
  • 劉臨風, 大西真由, 吉井優花, 安部賀央里, 頭金正博. Efficacy and Safety of Anti-rheumatic Drugs in Patients with Rheumatoid Arthritis: Bayesian Network Meta-Analysis. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
  • 劉臨風, 大西真由, 吉井優花, 安部賀央里, 頭金正博. Comparison of the efficacy and safety of various anti-rheumatic drugs for rheumatoid arthritis: Network Meta-Analysis. 日本臨床薬理学会学術総会抄録集(Web). 2023. 44th
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Education (2):
  • 1982 - 1984 Tohoku University Graduate School of Pharmaceutical Sciences
  • 1978 - 1982 Tohoku University Faculty of Pharmaceutical Sciences
Professional career (1):
  • 博士(理学) (東京工業大学)
Work history (6):
  • 2011/04 - 現在 Nagoya City University School of Pharmacy Profsser
  • 2002/04 - 2011/03 National Institute of Health Sciences Division of Medicinal Safety Science Chief
  • 1994/09 - 2002/03 National Institutes of Public Health Researcher
  • 1997/09 - 1998/12 National Institute of Health National Cancer Institute Guest Restcher
  • 1984/04 - 1994/08 Shionogi Co.,Ltd. Research Institute Researcher
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Awards (2):
  • 2022/06 - The Japanese Society of Toxicology Fizer Award Comparison of the developmental/reproductive toxicity and hepatotoxicity of phthalate esters in rats using an open toxicity data source J. Toxicol. Sci. Vol.44, No.4, 245-255, 2019
  • 2020/08 - 日本医療薬学会 医療薬学誌論文賞 ナショナルレセプトデータベースを用いた周術期せん妄の発症要因に 関する研究
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