Rchr
J-GLOBAL ID:200901056849841070
Update date: Jan. 31, 2024
Nishimura Yorihiro
ニシムラ ヨリヒロ | Nishimura Yorihiro
Affiliation and department:
Job title:
Senior Research Scientist
Research field (2):
Virology
, Veterinary medicine
Research keywords (3):
手足口病
, エンテロウイルス
, 受容体
Research theme for competitive and other funds (8):
- 2019 - 2023 神経細胞に特異的なエンテロウイルス71新規受容体の同定と機能解析
- 2019 - 2023 動物モデルを用いたエンテロウイルスD68による弛緩性麻痺発現機序の解明
- 2015 - 2018 Studies on the molecular mechanism of cell-entry inhibitors for hand-foot-and-mouth disease virus.
- 2013 - 2016 Changes in receptor specificity and pathogenesis associated with mutations of capsid amino acids of enterovirus 71 in host adaptation
- 2010 - 2014 The molecular basis of PSGL-1-dependent viral replication and pathogenesis in enterovirus 71 infection
- 2009 - 2010 Studies on the leukocyte-entry mechanism of the hand-foot-and-mouth disease virus
- 2005 - 2006 中枢神経障害をおこす手足口病ウイルスの感染機構に関する研究
- 1999 - 2000 ネコ免疫不全ウイルス感染ネコの免疫学的解析
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Papers (55):
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Minami Kikuchi Ueno, Kouichi Kitamura, Yorihiro Nishimura, Minetaro Arita. Evaluation of Direct Detection Protocols for Poliovirus from Stool Samples of Acute Flaccid Paralysis Patients. Viruses. 2023. 15. 10. 2113-2113
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Tomoyuki Shiota, Tian-Cheng Li, Yorihiro Nishimura, Sayaka Yoshizaki, Ryuichi Sugiyama, Masayuki Shimojima, Masayuki Saijo, Hiroyuki Shimizu, Ryosuke Suzuki, Takaji Wakita, et al. Integrin α3 is involved in non-enveloped hepatitis E virus infection. Virology. 2019. 536. 119-124
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Yong Zhang, Dongmei Yan, Shuangli Zhu, Yorihiro Nishimura, Xufang Ye, Dongyan Wang, Jaume Jorba, Hui Zhu, Hongqiu An, Hiroyuki Shimizu, et al. An Insight into Recombination with Enterovirus Species C and Nucleotide G-480 Reversion from the Viewpoint of Neurovirulence of Vaccine-Derived Polioviruses. SCIENTIFIC REPORTS. 2015. 5. 17291
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Yorihiro Nishimura, Noel P. McLaughlin, Jieyan Pan, Sara Goldstein, Susan Hafenstein, Hiroyuki Shimizu, Jeffrey D. Winkler, Jeffrey M. Bergelson. The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan Sulfate. PLoS Pathogens. 2015. 11. 10. e1005184
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Chikako Kataoka, Tadaki Suzuki, Osamu Kotani, Naoko Iwata-Yoshikawa, Noriyo Nagata, Yasushi Ami, Takaji Wakita, Yorihiro Nishimura, Hiroyuki Shimizu. The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model. PLOS PATHOGENS. 2015. 11. 7
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MISC (14):
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K. C. Ong, H. Shimizu, Y. Nishimura, M. Arita, D. Shamala, M. J. Cardosa, K. T. Wong. Phenotypic and Genotypic Characterization of Two Mouse Adapted Enterovirus 71 Strains that Showed Differences in Murine CNS Infection. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2008. 12. E74-E74
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實藤 雅文, 楠原 浩一, 後藤 多奉, 吉良 龍太郎, 西村 順裕, 清水 博之, 鳥巣 浩幸, 原 寿郎. コクサッキーウイルスA16の手足口病に伴って菱脳炎を呈した一例. NEUROINFECTION. 2008. 13. 2. 44-44
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西村順裕, 有田峰太郎, 吉田弘, 清水博之, 宮村達男. ポリオ野生株ウイルスの封じ込め対策に関する研究 ラオスAFP症例より分離された2型ワクチン由来ポリオウイルス. ポリオ野生株ウイルスの封じ込め対策に関する研究 平成17年度 総括・分担研究報告書. 2006
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Y Nishimura, M Shimojima, T Miyazawa, E Sato, K Nakamura, Y Izumiya, Y Ikeda, T Mikami, E Takahashi. Molecular cloning of the cDNAs encoding the feline B-lymphocyte activation antigen B7-1 (CD80) and B7-2 (CD86) homologues which interact with human CTLA4-Ig. EUROPEAN JOURNAL OF IMMUNOGENETICS. 2000. 27. 5-6. 427-430
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Y Nishimura, T Miyazawa, Y Ikeda, Y Izumiya, K Nakamura, E Sato, T Mikami, E Takahashi. Molecular cloning and sequencing of a cDNA encoding the feline cytotoxic T-lymphocyte-associated protein 4 (CTLA4) homologue. EUROPEAN JOURNAL OF IMMUNOGENETICS. 2000. 27. 2. 99-101
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Education (2):
- 1997 - 2000 The University of Tokyo Graduate School of Agricultural and Life Sciences Veterinary Medical Sciences
- 1991 - 1997 Yamaguchi University Faculty of Agriculture Veterinary Medicine
Professional career (1):
- (BLANK) (The University of Tokyo)
Work history (3):
- 2008 - 現在 国立感染症研究所 主任研究官
- 2003 - 2008 国立感染症研究所 研究員
- 1999 - 2003 日本学術振興会特別研究員
Awards (1):
- 2011/09 - The Japanese Society for Virology SUGIURA Memorial Incentive Award for Young Virologist Studies on the infection mechanism of enterovirus 71
Association Membership(s) (2):
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