Rchr
J-GLOBAL ID：200901057430319957
Update date: Apr. 04, 2024
Yoshida Kiyotsugu
ヨシダ キヨツグ | Yoshida Kiyotsugu
Affiliation and department：
Job title：
Porfessor
Research field (1)：
Tumor biology
Papers (85)：
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Eriko Harada, Saishu Yoshida, Yuta Imaizumi, Akira Kawamura, Takashi Ohtsuka, Kiyotsugu Yoshida. Dual-specificity tyrosine-regulated kinase 2 exerts anti-tumor effects by induction of G1 arrest in lung adenocarcinoma. Biochimica et biophysica acta. General subjects. 2024. 1868. 6. 130600-130600
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Chika Nakagawa, Tsunekazu Oikawa, Kohji Yamada, Akihito Tsubota, Chisato Saeki, Kuniko Katagiri, Naoko Tago, Hiroshi Kamioka, Kaoru Ueda, Koichiro Haruki, et al. Protein kinase C delta enhances the diagnostic performance of hepatocellular carcinoma. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2024. 1-13
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Yasuhiro Takano, Satomi Yogosawa, Yuta Imaizumi, Hiroshi Kamioka, Yumi Kanegae, Ken Eto, Kiyotsugu Yoshida. DYRK2 promotes chemosensitivity via p53-mediated apoptosis after DNA damage in colorectal cancer. Cancer science. 2023
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Hiroshi Kamioka, Satomi Yogosawa, Tsunekazu Oikawa, Daisuke Aizawa, Kaoru Ueda, Chisato Saeki, Koichiro Haruki, Masayuki Shimoda, Toru Ikegami, Yuji Nishikawa, et al. Dyrk2 gene transfer suppresses hepatocarcinogenesis by promoting the degradation of Myc and Hras. JHEP reports : innovation in hepatology. 2023. 5. 7. 100759-100759
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Kohji Yamada, Yoshito Hannya, Tsunekazu Oikawa, Ayano Yoshida, Kuniko Katagiri, Saishu Yoshida, Rei Koizumi, Naoko Tago, Yuya Shimoyama, Akira Kawamura, et al. Extended-Synaptotagmin 1 Enhances Liver Cancer Progression Mediated by the Unconventional Secretion of Cytosolic Proteins. Molecules (Basel, Switzerland). 2023. 28. 10
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MISC (30)：
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Kohji Yamada, Kiyotsugu Yoshida. Leakage? or Secretion? unconventional protein secretion in cancer. Oncotarget. 2023. 14. 1. 146-147
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及川恒一, 山田幸司, 坪田昭人, 佐伯千里, 上田薫, 神岡洋, 春木孝一郎, 池上徹, 吉田清嗣, 猿田雅之. 早期診断に有用な肝細胞癌特異的バイオマーカー血清PKCδ. 肝細胞研究会プログラム・抄録集. 2023. 30th
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Kohji Yamada, Kiyotsugu Yoshida. Multiple subcellular localizations and functions of protein kinase Cδ in liver cancer. World journal of gastroenterology. 2022. 28. 2. 188-198
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Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021. 17. 1. 1-382
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Saishu Yoshida, Kiyotsugu Yoshida. Multiple functions of DYRK2 in cancer and tissue development. FEBS letters. 2019. 593. 21. 2953-2965
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Lectures and oral presentations (37)：
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大腸がんに対するアデノウイルスベクターによるDYRK2過剰発現を用いた新規遺伝子治療
(日本外科学会定期学術集会抄録集 2021)
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肝臓癌におけるDYRK2の強制発現はアポトーシスを介して抗腫瘍効果を発揮する
(東京慈恵会医科大学雑誌 2019)
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DNA Methylation of Dual-Specificity Tyrosine-Regulated Kinase 2 (DYRK2) Promoter Regulates Proliferation of Human Colorectal Cancer
(JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS 2019)
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DYRK2のメチル化を標的とした大腸癌治療の可能性
(日本消化器外科学会総会 2019)
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DYRK2のプロモーター領域のメチル化はヒトの結腸直腸癌の進行を制御する(DNA methylation of DYRK2 promoter regulates progression of human colorectal cancer)
(日本癌学会総会記事 2018)
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Education (2)：
- 1993 - 1997 東京慈恵会医科大学大学院 医学研究科博士課程
- 1987 - 1993 東京慈恵会医科大学 医学部
Work history (6)：
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