Yabe Takeshi

ヤベタケシ | Yabe Takeshi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.setsunan.ac.jp/

Research field (2)： Other , Neuroscience - general

Research theme for competitive and other funds (21)：

2014 - 2015 平成26年糧食研究会研究支援 (研究代表者150万円)

2011 - 2014 損傷脳におけるPEDFの神経保護作用、及び神経再生促進作用の解析

2011 - 2013 Elicidation of action mechanism of Hochuekkito through immunomodulation of intestinal epithelial cells

2011 - 2012 平成22年度上原記念生命科学財団研究助成金(研究代表者 500万円)

2011 - 2012 平成22年度武田科学振興財団薬学系研究奨励 (研究代表者 300万円)

2011 - 2012 Role of orexinergic system in the mechanism underlying an antidepressant-like effect of kososan

2008 - 2011 脳傷害時におけるPEDFの役割の解明、及びその臨床応用に関する基礎的検討

2008 - 2011 脳障害時におけるPEDFの役割の解明、およびその臨床応用に関する基礎的検討

2009 - 2011 Study on clarification of action mechanism of a Kampo medicine, Hochuekkito through immunomodulating exosome

2009 - 2010 Involvement of orexin-A and neuropeptide Y in the antidepressant-like effect of kososan.

2005 - 2008 PEDFの神経保護作用の解析、及びその臨床応用のための基礎的検討

2007 - 2008 A possible mechanism underlying an antidepressive-like effect of kososan -A association of orexin-A with neurogenesis-

2005 - 2006 平成16年度武田科学振興財団薬学系研究奨励 (研究代表者 200万円)

2004 - 2005 平成15年度上原記念生命科学財団研究奨励金 (研究代表者 200万円)

1998 - 1999 平成9年度上原記念生命科学財団研究奨励金 (研究代表者 200万円)

1996 - 1997 Studies on anti-dementia effects of Kampo medicines and their active ingredients

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Papers (73)：

Ryota Araki, Ayami Kita, Yukio Ago, Takeshi Yabe. Chronic social defeat stress induces anxiety-like behaviors via downregulation of serotonin transporter in the prefrontal serotonergic system in mice. Neurochemistry International. 2024. 105682-105682
Ryota Araki, Yuki Tominaga, Ryo Inoue, Ayami Kita, Takeshi Yabe. 2′-Fucosyllactose Alleviates Early Weaning-Induced Anxiety-Like Behavior, Amygdala Hyperactivity, and Gut Microbiota Changes. Biological and Pharmaceutical Bulletin. 2023. 46. 6. 796-802
Ryota Araki, Shoji Nishida, Yui Oishi, Hayato Tachioka, Ayami Kita, Takeshi Yabe. Methyl Donor Supplementation Prevents a Folate Deficiency-induced Depression-like State and Neuronal Immaturity of the Dentate Gyrus in Mice. Neuroscience . 2022. 485. 12-22
Ryota Araki, Shoji Nishida, Yuki Nakajima, Arimi Iwakumo, Hayato Tachioka, Ayami Kita, and Takeshi Yabe. Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells. Heliyon. 2021. 7. 9. e08071
Ryota Araki, Hayato Tachioka, Ayami Kita, Hironori Fujiwara, Kazufumi Toume, Kinzo Matsumoto, Takeshi Yabe. Kihito prevents corticosterone-induced brain dysfunctions in mice. Journal of Traditional and Complementary Medicine. 2021

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MISC (11)：

Ken Ebihara, Hironori Fujiwara, Dya Fita Dibwe, Suresh Awale, Ryota Araki, Takeshi Yabe, Kinzo Matsumoto. Sex difference in autism spectrum disorder (ASD)-like behaviors caused by allopregnanolone (ALLO) biosynthesis inhibition and distribution of ALLO in the brain. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S224-S224
Kentaro Hata, Tomomi Sanagi, Takeshi Yabe, Haruki Yamada. Pigment epithelium-derived factor (PEDF) induces glutamate transporters expression in rat cultured astrocytes. NEUROSCIENCE RESEARCH. 2010. 68. E142-E142
Effects of i.c.v. injection of orexin A on cell proliferation in the dentate gyrus and behaviors. 2007. 27. 5. 305-305
伊藤直樹, 蒲生裕司, 永井隆之, 矢部武士, 及川哲郎, 山田陽城, 花輪壽彦. P-05 蘇葉成分rosmarinic acidの抗うつ様作用メカニズムの解析 : 海馬神経幹細胞挙動に与える影響(脳神経・精神,一般演題ポスター,第24回和漢医薬学会大会和漢薬の複雑さ-経験知と科学知-). 和漢医薬学雑誌. 2007. 24. 84-84
王強, 岩崎鋼, 鈴木朋子, 矢部武士, 鳥居塚和生, 花輪壽彦, 山田陽城, 佐々木英忠. 203 漢方処方加味温胆湯の老齢マウスにおける脳内アセチルコリンニューロンに対する効果:抗痴呆薬としての可能性. 日本東洋醫學雜誌. 2000. 50. 6. 206-206

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Books (3)：

薬学生のための漢方医薬学改訂第3版
南江堂 2017 ISBN:9784524403363
Pigment Epithelium-derived Factor: Chemistry, Structure, Biology, and Application
Hindawi 2012
薬学生のための漢方医薬学
南江堂 2007

Lectures and oral presentations (25)：

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Education (2)：

1989 - 1991 Tokyo University of Science Graduate School, Division of Pharmaceutical Sciences
1985 - 1989 Tokyo College of Pharmacy Faculty of Pharmaceutical Science

Professional career (3)：

Awards (4)：

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