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J-GLOBAL ID：200901057695071671   Update date: Apr. 22, 2024

Kobayashi Makoto

コバヤシ マコト | Kobayashi Makoto
Affiliation and department：
University of Tsukuba Institute of Medicine

About University of Tsukuba Institute of Medicine


Job title： Associate Professor
Research field  (6)： Developmental biology ,  Molecular biology ,  Medical biochemistry ,  Science education ,  Cell biology ,  Food sciences
Research keywords  (2)： ゼブラフィッシュ ,  遺伝子発現
Research theme for competitive and other funds  (41)：
  • 2023 - 2026 魚類急性毒性試験の動物福祉に配慮した試験への転換に向けた研究
  • 2022 - 2024 Functions of supersulfide in animal development
  • 2021 - 2024 Development of a rubric to foster researchers' visual communication design skills
  • 2021 - 2023 超短命アフリカメダカを用いた各種抗酸化食品成分のアンチエージング効果の研究
  • 2020 - 2023 Novel screening system expressing human metabolic enzymes in vivo
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Papers (120)：
  • Takeuchi, Ichiro, Tanase-Nakao, Kanako, Ogawa, Ayame, Sugawara, Tohru, Migita, Osuke, Kashima, Makoto, Yamazaki, Touko, Iguchi, Akihiro, Naiki, Yasuhiro, Uchiyama, Toru, et al. Congenital anaemia associated with loss-of-function variants in DNA polymerase epsilon 1. J. Med. Genet. 2023. 61. 3. 239-243
  • Tamaoki, Junya, Maeda, Hiroki, Kobayashi, Isao, Takeuchi, Miki, Ohashi, Ken, Gore, Anike, Bonkhofer, Florian, Patient, Roger, Weinstein, Brant M, et al. LSD1 promotes the egress of hematopoietic stem and progenitor cells into the bloodstream during the endothelial-to-hematopoietic transition. Dev. Biol. 2023. 501. 92-103
  • Zhu, Lida, Makita, Shuichi, Tamaoki, Junya, Lichtenegger, Antonia, Lim, Yiheng, Zhu, Yiqiang, Kobayashi, Makoto, Yasuno, Yoshiaki. Multi-focus averaging for multiple scattering suppression in optical coherence tomography. Biomed. Opt. Express. 2023. 14. 9. 4828-4844
  • Tomita, Kiriko, Makita, Shuichi, Fukutake, Naoki, Morishita, Rion, Abd El-Sadek, Ibrahim, Mukherjee, Pradipta, Lichtenegger, Antonia, Tamaoki, Junya, Bian, Lixuan, Kobayashi, Makoto, et al. Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging. Biomed. Opt. Express. 2023. 14. 7. 3100-3124
  • Lixuan Bian, Vu Thanh Nguyen, Junya Tamaoki, Yuka Endo, Guilin Dong, Ayaka Sato, Makoto Kobayashi. Genetic hyperactivation of Nrf2 causes larval lethality in Keap1a and Keap1b-double-knockout zebrafish. Redox biology. 2023. 62. 102673-102673
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MISC (3)：
  • 小林 麻己人, 三輪 佳宏. SB-5 実例! : サイエンスイラストの自力改良にチャレンジ!(SB サイエンスイラストをセンス良く美しく描く法則【公開シンポジウム】,シンポジウム). 日本微生物生態学会講演要旨集. 2011. 27. 44-44
  • 飯田敦夫, 坂口和弥, 佐藤洋旭, 桜井英俊, 西邨大吾, 岩木彩, 竹内美紀, 小林麻己人, 米村重信, 川原敦雄, et al. 血液循環の始まりはメタロプロテアーゼに依存しておこる. ワークショップ「細胞接着・ECM・ 細胞間相互作用」(座長:橋本隆,西村智),第62 回日本細胞生物学会大会(2010.5.20 大阪). 2010
  • C Kimura-Yoshida, Oda-Ishii, I, M Kobayashi, S Aizawa, Matsuo, I. Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head development. DEVELOPMENTAL BIOLOGY. 2004. 271. 2. 564-564
Patents (1)：
  • 抗酸化剤
Books (9)：
  • 動物実験代替法とNew Approach Methodologiesの開発・利用動向
    2023 ISBN:9784781317472
  • スパイス・ハーブの機能と応用
    恒星社厚生閣シーエムシー出版 2020
  • 魚類発生学の基礎
    恒星社厚生閣 2018 ISBN:9784769914853
  • 南山堂 医学大辞典 20版
    南山堂 2015
  • ADVANCES IN ENZYME REGULATION, VOL 46, PROCEEDINGS
    ELSEVIER SCIENCE BV 2006
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Lectures and oral presentations  (309)：
  • Disperse scatterer model of OCT and its application to design volumetric differential contrast imaging
    (Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, Photonics West BiOS)
  • Multiple scattering suppression by multi-focus averaging in Jones-matrix optical coherence tomography
    (Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, Photonics West BiOS)
  • Non-invasive and label-free zebrafish investigations using polarization-sensitive optical coherence tomography
    (Label-free Biomedical Imaging and Sensing (LBIS) 2023, Photonics West BiOS)
  • Volumetric differential contrast imaging by computationally augmented optical coherence tomography microscopy
    (Label-free Biomedical Imaging and Sensing (LBIS) 2023, Photonics West BiOS)
  • Genetic hyperactivation of Nrf2 causes larval lethality in zebrafish.
    (第45回日本分子生物学会年会)
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Works (1)：
  • 研究のビジュアルデザイン(WEBサイト)
    田中, 佐代子, 小林, 麻己人, 三輪, 佳宏, 王, 宛亦, 苗木, 愛 2020 - 現在
Education (3)：
  • - 1992 The Graduate University for Advanced Studies Graduate School, Division of Life Science
  • - 1989 Keio University Graduate School, Division of Science and Engineering
  • - 1987 Keio University Faculty of Science and Engineering
Work history (8)：
  • 2021/12 - 現在 筑波大学 医学医療系 准教授
  • 2011/10 - 2021/11 University of Tsukuba Faculty of Medicine
  • 2008/04 - 2011/09 University of Tsukuba Graduate School of Comprehensive Human Sciences
  • 1998/04 - 2008/03 University of Tsukuba Institute of Basic Medical Sciences
  • 2003/01 - 2007/03 科学技術振興機構 山本環境応答プロジェクト グループリーダー(兼任)
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Committee career (10)：
  • 2022/11 - 現在 ゼブラフィッシュ・メダカ創薬研究会 組織委員
  • 2022/11 - 現在 ゼブラフィッシュ・メダカ創薬研究会 第9回大会 運営委員長
  • 2020/05 - 現在 Int J Mol Sci誌 Editorial Board Member
  • 2010/10 - 現在 日本サイエンスビジュアリゼーション研究会 運営幹事
  • 2004/04 - 現在 転写研究会 運営委員
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Association Membership(s) (10)：
日本農芸化学会 ,  日本細胞生物学会 ,  Society for Redox Biology and Medicine ,  International Zebrafish Society ,  Zebrafish Disease Models Society ,  日本酸化ストレス学会 ,  American Society for Microbiology ,  Japanese Society of Developmental Biologists ,  The Molecular Biology Society of Japan ,  THE JAPANESE BIOCHEMICAL SOCIETY
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