Inoue Asuka

イノウエアスカ | Inoue Asuka

Affiliation and department：
Job title： Professor
Other affiliations (1)：

Research field (3)： Pharmacology , Pharmaceuticals - health and biochemistry , Functional biochemistry

Research keywords (1)： GPCR

Research theme for competitive and other funds (14)：

2009 - 現在 Development of a nobel assay system to detect activation of G protein-coupled receptors (GPCRs)
2008 - 現在体毛形成におけるリゾホスファチジン酸の生理機能の解析
2021 - 2026 Structural dynamics of GPCR in cells
2021 - 2025 Manipulation of G12/13 signaling and and drug development strategy
2021 - 2024 Multi-scale platform for untangling physiological complexity

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Papers (230)：

Masumi Oka, Sohta Akaki, Osamu Ohno, Maho Terasaki, Yuho Hamaoka-Tamura, Michiko Saito, Shinichi Kato, Asuka Inoue, Junken Aoki, Kenji Matsuno, et al. Suppression of Mast Cell Activation by GPR35: GPR35 Is a Primary Target of Disodium Cromoglycate. The Journal of pharmacology and experimental therapeutics. 2024. 389. 1. 76-86
Tharindunee Jayakody, Asuka Inoue, Srinivasaraghavan Kannan, Gaku Nakamura, Kouki Kawakami, Krishan Mendis, Thanh-Binh Nguyen, Jianguo Li, Deron R Herr, Chandra S Verma, et al. Mechanisms of biased agonism by Gαi/o-biased stapled peptide agonists of the relaxin-3 receptor. Science signaling. 2024. 17. 823. eabl5880
Ryoji Kise, Asuka Inoue. GPCR signaling bias: an emerging framework for opioid drug development. The Journal of Biochemistry. 2024. 175. 4. 367-376
Dayana Abboud, Clauda Abboud, Asuka Inoue, Jean-Claude Twizere, Julien Hanson. Basal interaction of the orphan receptor GPR101 with arrestins leads to constitutive internalization. Biochemical Pharmacology. 2024. 220. 116013-116013
Geng Chen, Nico Staffen, Zhangsong Wu, Xinyu Xu, Jinheng Pan, Asuka Inoue, Tingyi Shi, Peter Gmeiner, Yang Du, Jun Xu. Structural and functional characterization of the endogenous agonist for orphan receptor GPR3. Cell Research. 2024. 34. 3. 262-265

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MISC (226)：

新井大輝, 辰己茉菜絵, 生田達也, 川上耕季, 井上飛鳥. Analysis of αN helix function in Gα protein activation. 日本薬学会年会要旨集(Web). 2023. 143rd
中村楽, 川上耕季, 生田達也, 井上飛鳥. Analysis of biased-signal creation substrates and mechanisms in GPCRs. 日本薬学会年会要旨集(Web). 2023. 143rd
CARINO Carlo Marion Codog, 生田達也, 倉本律輝, 川上耕季, 内田安則, 田口友彦, 井上飛鳥. Novel PIP₂ binding site of β arrestin and its function. 日本薬学会年会要旨集(Web). 2023. 143rd
九川真衣, 木瀬亮次, 福田昌弘, 川上耕季, 松井俊貴, 小林和弘, 井上飛鳥, 加藤英明, 加藤英明. 短鎖脂肪酸受容体FFAR2のリガンド認識機構と活性化機構の解明. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
福永彩美, 小柳淳暉, 福田昌弘, 川上耕季, 松井俊貴, 小林和弘, SCOTT Daniel J., 井上飛鳥, 加藤英明, 加藤英明. バソプレシン受容体1aによる神経ペプチドホルモン認識の構造基盤. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)

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Professional career (1)：

Work history (2)：

2024/04 - 現在 Kyoto University Graduate School of Pharmaceutical Sciences Professor
2022/04 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences Professor

Association Membership(s) (2)：

日本薬学会 , 日本生化学会

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