Research field (3)：
Cell biology
, Neuroscience - general
, Biological, health, and medical informatics
Research keywords (10)：
神経再生
, タンパク質構造
, in silico 薬剤設計
, 幹細胞
, 神経工学
, nerve regeneration
, protein structure
, in silico drug design
, stem cells
, neuronal technology
Research theme for competitive and other funds (4)：
2014 - 2017 Design and synthesis of anti-tuberculosis triclosan analogs with in silico tailered chemical structure library
2007 - 2009 Study of neurite elongation mechanisms of early-late endosome transfer
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Papers (53)：
Yosuke Ochi, Takanori Matsui, Keitaro Inoue, Kohei Monobe, Hiroshi Sakamoto, Shunsuke Aoki, Junichi Taira. Computational Screening and Experimental Validation of Inhibitor Targeting the Complex Formation of Grb14 and Insulin Receptor. Molecules. 2023. 29. 1. 198-198
Junichi Taira, Miho Yamaguchi, Anju Tashiro, Asuka Kida, Ko Suzuki, Katsuya Sakai, Kunio Matsumoto, Shunsuke Aoki. Computer-Assisted Identification of Inhibitor with Novel Pharmacophore Targeting First Kringle Domain of Hepatocyte Growth Factor. ChemistrySelect. 2023. 8. 36
Junichi Taira, Kahori Murakami, Kohei Monobe, Kohei Kuriki, Miu Fujita, Yosuke Ochi, Hiroshi Sakamoto, Shunsuke Aoki. Identification of novel inhibitors for mycobacterial polyketide synthase 13 via in silico drug screening assisted by the parallel compound screening with genetic algorithm-based programs. The Journal of Antibiotics. 2022
Junichi Taira, Tomohiro Umei, Keitaro Inoue, Mitsuru Kitamura, Francois Berenger, James C. Sacchettini, Hiroshi Sakamoto, Shunsuke Aoki. Improvement of the novel inhibitor for Mycobacterium enoyl-acyl carrier protein reductase (InhA): a structure-activity relationship study of KES4 assisted by in silico structure-based drug screening. Journal of Antibiotics. 2020
Junichi Taira, Toshiki Nagano, Mitsuru Kitamura, Miho Yamaguchi, Hiroshi Sakamoto, Shunsuke Aoki. Structural modification of a novel inhibitor for mycobacterium enoyl-acyl carrier protein reductase assisted by in silico structure-based drug screening. International Journal of Mycobacteriology. 2020. 9. 1. 12-17
Identification of novel chemical inhibitors for hepatocyte growth factor by in silico structure-based drug screening.
(CBI/JSBi/Omix 2012合同大会 生命医薬情報学連合大会 2012)
分子動力学計算によるUCH-L1変異体の構造変化予測
(第30回バイオ情報学研究会 2012)
in silico structure-based drug screening手法を用いたMycobacteriumに対する新規抗菌作用化合物の同定
(in silico structure-based drug screening手法を用いたMycobacteriumに対する新規抗菌作用化合物の同定 2012)
Identification of novel potential antibiotics for Staphylococcus by Structure-Based Drug Screening
(第30回バイオ情報学研究会 (SIG-BIO) 2012)
Identification of novel potential antibiotics for Staphylococcus by Structure-Based Drug Screening
(2012)
2015 - 現在 Kyushu Institute of Technology Faculty of Computer Science and Systems Engineering, Department of Bioscience and Bioinformatics
2018/04 - 2020/03 Kyushu Institute of Technology Faculty of Computer Science and Systems Engineering
2008 - 2015 Kyushu Institute of Technology Faculty of Computer Science and Systems Engineering, Department of Bioscience and Bioinformatics
2008 - 2015 Associate Professor,Department of Bioscience and Bioinformatics,Faculty of Computer Science and Systems Engineering,Kyushu Institute of Technology
2015 - Professor,Department of Bioscience and Bioinformatics,Faculty of Computer Science and Systems Engineering,Kyushu Institute of Technology
