Rchr
J-GLOBAL ID：200901058148419902   Update date: Feb. 01, 2024

Tanaka Kozo

タナカ コウゾウ | Tanaka Kozo
Affiliation and department：
Tohoku University Department of Molecular Oncology, Division of Cancer Control, Institute of Development, Aging and Cancer

About Tohoku University Department of Molecular Oncology, Division of Cancer Control, Institute of Development, Aging and Cancer


Job title： Professor
Homepage URL  (2)： http://www2.idac.tohoku.ac.jp/dep/molonc/index.html ,  http://www2.idac.tohoku.ac.jp/dep/molonc/pg40.html
Research field  (3)： Pathobiochemistry ,  Cell biology ,  Molecular biology
Research keywords  (4)： chromosomal instability ,  chromosome segregation ,  Molecular oncology ,  Cellular biology
Research theme for competitive and other funds  (27)：
  • 2007 - 現在 Mechanisms of accurate chromosome segregation
  • 2007 - 現在 Mitosis-targeted anti-cancer therapies
  • 2023 - 2025 分裂期染色体の可塑性が染色体分配に及ぼす影響の解明
  • 2022 - 2025 がん細胞の染色体不安定性の原因としての染色体オシレーション減弱機構の解明
  • 2022 - 2024 Role of oxidative stress in chromosomal insability with age
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Papers (82)：
  • Guan Chen, Zhenhua Li, Kenji Iemura, Kozo Tanaka. Oxidative stress induces chromosomal instability through replication stress in fibroblasts from aged mice. Journal of cell science. 2023. 136. 11
  • Riko Irikura, Hironari Nishizawa, Kazuma Nakajima, Mie Yamanaka, Guan Chen, Kozo Tanaka, Masafumi Onodera, Mitsuyo Matsumoto, Kazuhiko Igarashi. Ferroptosis model system by the re-expression of BACH1. Journal of biochemistry. 2023
  • Norihisa Shindo, Kazuki Kumada, Kenji Iemura, Jun Yasuda, Haruna Fujimori, Mai Mochizuki, Keiichi Tamai, Kozo Tanaka, Toru Hirota. Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1. Cell reports. 2022. 41. 9. 111723-111723
  • 家村 顕自, 田中 耕三. 染色体不安定性に対するがん細胞の生存戦略(Survival strategies of cancer cells against chromosomal instability). 日本癌学会総会記事. 2022. 81回. J-1033
  • Masayoshi Nagai, Kenji Iemura, Takako Kikkawa, Sharmin Naher, Satoko Hattori, Hideo Hagihara, Koh ichi Nagata, Hayato Anzawa, Risa Kugisaki, Hideki Wanibuchi, et al. Deficiency of CHAMP1, a gene related to intellectual disability, causes impaired neuronal development and a mild behavioral phenotype. Brain Communications. 2022. 4. 5. fcac20
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MISC (56)：
  • 池田真教, 鈴木康弘, 田中耕三, 佐藤靖史. Understanding of a spatiotemporal regulation of α-tubulin detyrosination. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 家村顕自, 田中耕三. Mitotic chromosome oscillation maintains chromosomal stability. 日本細胞生物学会大会(Web). 2021. 73rd
  • 家村顕自, 田中耕三. 分裂期染色体動態異常を介した染色体不安定性の発生機構. 日本癌学会学術総会抄録集(Web). 2021. 80th
  • 家村顕自, 田中耕三. Chromosome oscillation-mediated robust equal segregation system is suppressed together with progression of cellular senescence. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
  • 家村顕自, 田中耕三. がん細胞の増殖優位性獲得過程における染色体不安定性の役割. 日本生化学会大会(Web). 2021. 94th
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Education (2)：
  • - 1997 The University of Tokyo Graduate School, Division of Medical Sciences Internal Medicine
  • - 1991 The University of Tokyo Faculty of Medicine Medaical Department
Professional career (1)：
  • 博士(医学) (The University of Tokyo)
Work history (9)：
  • 2011/03 - 現在 Department of Molecular Oncology, Institute of Development, Aging and Cancer, Tohoku University Professor
  • 2008/10 - 2011/02 Institute of Development, Aging and Cancer, Tohoku University Associate Professor
  • 2007/03 - 2008/09 東北大学特定領域研究推進支援センター Associate Professor
  • 2002/01 - 2007/02 College of Life Science, University of Dundee, UK Post-doctral research assistant
  • 1998/04 - 2001/12 広島大学原爆放射能医学研究所分子病理学研究分野 助手
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Committee career (4)：
  • 2018/06 - 現在 Japan Society for Cell Biology Representative
  • 2015/01 - 現在 日本生化学会 評議員
  • 2010/01 - 現在 日本癌学会 評議員
  • 2010/01 - 2012/12 日本癌学会 評議員
Awards (1)：
  • 2001/06/09 - 広島大学医学部医学科同窓会広仁会 広島大学医学部広仁会基礎医学研究賞 相同組換え遺伝子による効率的なジーン・ターゲティング法の開発
Association Membership(s) (5)：
THE JAPANESE BIOCHEMICAL SOCIETY ,  Japan Society for Cell Biology ,  The Japanese Society of Internal Medicine ,  The Molecular Biology Society of Japan ,  日本癌学会(2010/01- 評議員)
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